Plantanone B  (Synonyms: Kaempferol 3-O-rhamnosylgentiobioside)

Plantanone B is a moderate antioxidant-agent with an IC₅₀ of 169.8±5.2 μM. Plantanone B shows significant ovine COX-1 and moderate COX-2 inhibitory activities. Plantanone B has the potential for inflammation-related diseases research^[1].

The antioxidant activity of Plantanone B is measured by the DPPH method. Plantanone B exhibits a moderate antioxidant activity, with an IC₅₀ value of 169.8±5.2 μM^[1].
Plantanone B?inhibits COX-1 preferentially over COX-2 with selectivity index (SI) value of 0.49. It shows significant inhibitory activities against ovine COX-1 and COX-2 at concentration of 50 μM, with the inhibition of 76.18% and 21.78%, respectively^[1].
.Plantanone B?shows significant COX-1 and moderate COX-2 inhibitory activities with IC₅₀?values of 21.78±0.20 μM for COX-1, as well as 44.01±0.42 μM for COX-2, respectively^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

756.66

C₃₃H₄₀O₂₀

55780-30-8

Solid

Off-white to light yellow

O=C1C(O[C@H](O[C@@H]2CO[C@@H]([C@@H]([C@H]3O)O)O[C@@H]([C@H]3O)CO)[C@@H]([C@H]([C@@H]2O)O)O[C@H](O[C@H]4C)[C@@H]([C@@H]([C@H]4O)O)O)=C(C(C=C5)=CC=C5O)OC6=CC(O)=CC(O)=C16

Room temperature in continental US; may vary elsewhere.

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

• [1]. Jun-Wei He, et al. Anti-inflammatory and antioxidant activities of flavonoids from the flowers of Hosta plantaginea RSC Adv., 2018, 8, 18175-18179