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Results for "

quinoline

" in MedChemExpress (MCE) Product Catalog:

By Targets:	AAK1 (2) Acetyl-CoA Carboxylase (1) ADC Cytotoxin (1) Amyloid-β (1) Antibiotic (6) Apoptosis (6) ATM/ATR (1) ATP Synthase (1) Autophagy (3) Bacterial (8) Biochemical Assay Reagents (5) Carbonic Anhydrase (1) Caspase (2) DNA/RNA Synthesis (3) EGFR (2) Endogenous Metabolite (4) FAK (1) FAP (1) Fluorescent Dye (7) Fungal (4) HBV (1) Histone Methyltransferase (1) HIV (2) HIV Integrase (1) Isotope-Labeled Compounds (2) JNK (1) Leukotriene Receptor (1) Lipoxygenase (1) Microtubule/Tubulin (2) Mitochondrial Metabolism (1) Mixed Lineage Kinase (1) Necroptosis (1) NF-κB (1) P-glycoprotein (3) Parasite (10) PARP (1) Pim (1) Potassium Channel (3) RET (1) RIP kinase (1) ROS Kinase (3) SARS-CoV (3) Sirtuin (2) TNF Receptor (1) Topoisomerase (1) URAT1 (1) VEGFR (1) Xanthine Oxidase (1)
By Research Areas:	Cancer (28) Cardiovascular Disease (2) Infection (26) Inflammation/Immunology (13) Metabolic Disease (8) Neurological Disease (3)
Click Chemistry:	Azide (1)

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

Natural
Products

Isotope-Labeled Compounds

Click Chemistry

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W719475

Quinoline-d7	Isotope-Labeled Compounds	Others
Quinoline-d7 is the deuterium labeled Quinoline .

HY-W002011

Quinoline-2-carboxylic acid	Endogenous Metabolite	Metabolic Disease
Quinoline-2-carboxylic acid is an endogenous metabolite.

HY-12305

Q-VD-OPh Maximum Cited Publications 53 Publications Verification QVD-OPH; quinoline-Val-Asp-Difluorophenoxymethylketone	Caspase HIV	Infection Cancer
Q-VD-OPh is an irreversible pan-caspase inhibitor with potent antiapoptotic properties; inhibits caspase 7 with an IC₅₀ of 48 nM and 25-400 nM for other caspases including caspase 1, 3, 8, 9, 10, and 12. Q-VD-OPh can inhibits HIV infection. Q-VD-OPh is able to cross the blood-brain barrier.

HY-114002

Anticancer agent 129	Others	Cancer
Anticancer agent 129 (Compound 3a), a quinoline derivative, predicting to has anti-cancer activity .

HY-W002011S

Quinoline-2-carboxylic acid-d6	Endogenous Metabolite	Metabolic Disease
Quinoline-2-carboxylic acid-d₆ is the deuterium labeled Quinoline-2-carboxylic acid[1]. Quinoline-2-carboxylic acid is an endogenous metabolite.

HY-W004855

Quinoline-6-carboxylic acid	Biochemical Assay Reagents	Others
Quinoline-6-carboxylic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-D0290

Quinoline yellow 2SF	Fluorescent Dye	Others
Quinoline yellow 2SF is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.

HY-121462

Cyanine quinoline Blue	Biochemical Assay Reagents	Others
Cyanine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W344938

C.I. Acid yellow 3 quinoline yellow	Fluorescent Dye	Others
C.I. Acid yellow 3 is an anionic quinolinone dye that is commonly used as a food additive, but also in the cosmetic and pharmaceutical industries .

HY-116021

Buquinolate	Parasite	Infection
Buquinolate is a quinoline derivative. Buquinolate is effective in preventing coccidiosis of chickens .

HY-156642

(1-OH)-Exatecan	ADC Cytotoxin Topoisomerase	Cancer
(1-OH)-Exatecan is a quinoline ring compound. (1-OH)-Exatecan has substantial antiproliferative effects. (1-OH)-Exatecan can be used for cancer diseases research .

HY-D0096

*3-(2-Furoyl)quinoline-2-carboxaldehyde*	Fluorescent Dye	Others
3-(2-Furoyl)quinoline-2-carboxaldehyde is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.

HY-146303

C-RAF kinase-IN-1	Others	Cancer
C-RAF kinase-IN-1 (compound 1l) is a potent inhibitor of C-RAF kinase with an IC₅₀ of 0.193 μM. C-RAF kinase-IN-1 is a quinoline derivative. C-RAF kinase-IN-1 has the potential for the research of cancer diseases .

HY-143409

Antimalarial agent 10	Parasite	Infection
Antimalarial agent 10 (Compound 17b) is an aminoalcohol quinoline compound. Antimalarial agent 10 is an antimalarial agent with IC₅₀ values of 14.9 nM and 11.0 nM against respectively Pf3D7 and PfW2 and a selectivity index higher than 770 whatever the cell line is .

HY-144029

RET-IN-13	RET	Cancer
RET-IN-13 (compound 1), a quinoline compound, is a potent RET inhibitor with IC₅₀s of 0.5 nM, 0.9 nM for RET (WT) and RET (V804M), respectively. RET-IN-13 has the potential for tumors or intestinal diseases related to abnormal activation of RET research .

HY-137331

FAPI-46 1 Publications Verification	FAP	Cancer
FAPI-46 is a quinoline-based fibroblast activation protein (FAP)-targeted radiotracer. FAPI-46 has higher tumor uptake and prolonged tumor accumulation. FAPI-46 can be used for tumor imaging of a multitude of different cancers .

HY-144302

AAK1-IN-3	AAK1	Neurological Disease
AAK1-IN-3, a quinoline analogue, is a brain-penetrant adaptor protein 2-associated kinase 1 (AAK1) inhibitor with an IC₅₀ of 11 nM. AAK1-IN-3 has the potential for neuropathic pain research .

HY-144302A

AAK1-IN-3 TFA	AAK1	Neurological Disease
AAK1-IN-3 TFA, a quinoline analogue, is a brain-penetrant adaptor protein 2-associated kinase 1 (AAK1) inhibitor with an IC₅₀ of 11 nM. AAK1-IN-3 has the potential for neuropathic pain research .

HY-157045

ATP Synthesis-IN-1	ATP Synthase	Infection
ATP Synthesis-IN-1 (Compound 4), quinoline derivative, is a potent inhibitor of PA ATP synthesis activity. ATP Synthesis-IN-1 has PA ATP synthesis inhibition with IC₅₀ value of 11.1μg/mL. ATP Synthesis-IN-1 also has antibacterial activity. ATP Synthesis-IN-1 can be used for the research of drug-resistant PA infection .

HY-144047

HBV-IN-16	HBV DNA/RNA Synthesis	Infection
HBV-IN-16 is a potent inhibitor of covalently closed circular DNA (cccDNA). cccDNA serves as the template for viral RNA transcription and subsequent viral DNA generation. HBV-IN-16 is a quinoline derivative. HBV-IN-16 has the potential for the research of HBV infection (extracted from patent WO2019121357A1, compound 1) .

HY-W003017

5-Quinolinylboronic acid Quinolin-5-ylboronic	Biochemical Assay Reagents	Others
Quinoline-5-boronic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W007403

6-Bromoquinoline 6-Br-quinoline	Biochemical Assay Reagents	Others
6-Bromoquinoline is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-D0475

C.I.Solvent yellow 176	Fluorescent Dye
C.I.Solvent yellow 176 is a quinoline dye.

HY-W110662

Transtorine	Bacterial	Infection
Transtorine is a quinoline alkaloid, found from Ephedra transitoria, with antibacterial activity .

HY-W020111

7-Chloro-4-(piperazin-1-yl)quinoline	Sirtuin Parasite	Infection
7-Chloro-4-(piperazin-1-yl)quinolone is an important scaffold in medicinal chemistry. 7-Chloro-4-(piperazin-1-yl)quinolone is a potent sirtuin inhibitor and also inhibits the serotonin uptake (IC₅₀ of 50 μM). 7-Chloro-4-(piperazin-1-yl)quinolone exhibits antimalarial activity on D10 and K1 strains of *P. falciparum* with IC₅₀s of 1.18 μM and 0.97 μM, respectively .

HY-146373

Antibacterial agent 95	Bacterial	Infection
The minimum inhibitory concentration (MIC) of a new 2- (quinoline-4-methoxy) acetamide antituberculotic agent against the reference strain of Mycobacterium tuberculosis H37Rv was as low as 0.3 μ M. It also inhibited the growth of Mycobacterium tuberculosis in the macrophage model of tuberculosis infection.

HY-118911

ATM Inhibitor-10	ATM/ATR	Cancer
ATM Inhibitor-10 (compound 74), a 3-quinoline carboxamide, is a highly selective and orally active ATM inhibitor (IC₅₀: 0.6 nM). ATM Inhibitor-10 has anti-tumor activity in SW620 xenograft models. ATM Inhibitor-10 is synergistic with Top I inhibitors .

HY-120571

L-674573	Leukotriene Receptor	Cancer
L-674573 is a quinoline leukotriene synthesis inhibitor that selectively inhibits 5-lipoxygenase translocation .

HY-17013

Dofequidar	P-glycoprotein	Cancer
Dofequidar(MS-209) is a novel quinoline compound, which can reverse P-glycoprotein (P-gp)-mediated MDR.

HY-10522

LEDGIN6 4 Publications Verification CX05168; CX04328	HIV HIV Integrase	Infection
LEDGIN6 (CX05168) is a quinoline-based protein-protein interaction inhibitor of LEDGF/p75 and HIV integrase .

HY-17013D

Dofequidar sesquifumarate MS-209 sesquifumarate	P-glycoprotein	Cancer
Dofequidar sesquifumarate (MS-209) is a novel quinoline compound, which can reverse P-glycoprotein (P-gp)-mediated MDR .

HY-116433

Nequinate	Parasite Xanthine Oxidase	Infection Metabolic Disease
Nequinate, a quinoline compound, is an anticoccidial agent against cecal coccidiosis (Eimeria tenella) infections . Nequinate inhibits xanthine oxidoreductase (XOD) activity .

HY-148040

VEGFR-2-IN-29	VEGFR	Cancer
VEGFR-2-IN-29 (Compound 5) is a VEGFR-2 inhibitor with an IC₅₀ of 16.5 nM .

HY-155704

Lyciumamide A	Others	Others
DPP-IV-IN-5 is isolated from the fruits of Lycium barbarum. DPP-IV-IN-5 exerts moderate agonistic activities for peroxisome proliferator-activated receptor (PPARγ) with EC₅₀ values of 10.09 - 44.26 μM and also presents inhibitory activity on dipeptidyl peptidase-4 (DPPIV) with an IC₅₀ value of 47.13 μM .

HY-120786

MPT0B014 6-(3′,4′,5′-Trimethoxybenzoyl)quinoline	Microtubule/Tubulin Apoptosis	Cancer
MPT0B014 is a tubulin polymerization inhibitor. MPT0B014 induces cancer cell apoptosis. MPT0B014 can be used for the research of cancer .

HY-13743

Roquinimex Linomide; FCF89; ABR212616	TNF Receptor	Inflammation/Immunology
Roquinimex (Linomide; PNU212616; ABR212616) is a quinoline derivative immunostimulant which increases NK cell activity and macrophage cytotoxicity; inhibits angiogenesis and reduces the secretion of TNF alpha.

HY-156021

Antitubercular agent-40	Bacterial	Infection
Antitubercular agent-40 (compound 93) is a thieno[2,3-b]quinoline-2-carboxamide compound with potential antitubercular activity .

HY-116021S

Buquinolate-13C3	Isotope-Labeled Compounds Parasite	Infection
Buquinolate-13C3 is the ¹³C₃ labeled Buquinolate. Buquinolate is a quinoline derivative, which is developed as a coccidiostat for the prevention of coccidiosis in poultry .

HY-152249

Antibacterial agent 131	Antibiotic Bacterial Fungal	Infection
Antibacterial agent 131 is a quinoline derivative. Antibacterial agent 131 has antimicrobial effect. Antibacterial agent 131 destroys the integrity of the fungal cells via blocking ergosterol production .

HY-105507

PF-10040	Others	Inflammation/Immunology
PF-10040 is a quinoline derivative that can inhibit PAF-induced airway hyperresponsiveness. PF-10040 also shows protective effect in experimental NSAID-gastritis .

HY-59208

4-Quinolinol Kynurine	Endogenous Metabolite	Neurological Disease Cancer
4-Quinolone (Kynurine) is a quinoline derivative. Kynurine pathway modulates tryptophan metabolism and involves in neuroprotective effect. Kynurine promotes tumor cell survival and motility by suppressing antitumor immune .

HY-12305A

(R)-Q-VD-OPh (R)-QVD-OPH; (R)-quinoline-Val-Asp-Difluorophenoxymethylketone	Apoptosis	Cancer
(R)-Q-VD-OPh ((R)-QVD-OPH) is the less active enantiomer of Q-VD-OPha. Q-VD-OPha is an irreversible pan-caspase inhibitor with potent antiapoptotic properties.

HY-155244

12R-LOX-IN-2	Lipoxygenase DNA/RNA Synthesis	Inflammation/Immunology
12R-LOX-IN-2 (compound 7b) is an inhibitor of 12R-lipoxygenase (12R-LOX). 12R-LOX-IN-2 inhibits imiquimod (IMQ)-induced hyperproliferation of psoriatic keratinocytes and suppresses colony formation. 12R-LOX-IN-2 also reduced the protein level of Ki67 and the mRNA expression of IL-17A in IMQ-induced cells. 12R-LOX-IN-2 can be used in research into psoriasis and other skin-related inflammatory diseases .

HY-133031

CSV0C018875	Histone Methyltransferase	Cancer
CSV0C018875 is a quinoline-based EHMT2/G9a inhibitor. CSV0C018875 exhibits lesser cytotoxicity than BIX-01294 .

HY-147240

Acloproxalap ADX-629	Others	Infection Cardiovascular Disease Inflammation/Immunology
Acloproxalap is a quinoline-based aldehyde scavenger that can be used in studies of diseases with toxic aldehyde accumulation, such as inflammatory diseases of the eye and skin, respiratory diseases such as pneumonia, organ diseases, and viral infection-related syndromes .

HY-D2095

Medical fluorophore 33	Fluorescent Dye	Cancer
Medical fluorophore 33 is a novel quinoline-isoquinoline salt. Medical fluorophore 33 exhibits a strong fluorescent signal, good microsomal stability and high biocompatibility in vivo. Medical fluorophore 33 has antitumor activity in colorectal cancer mice .

HY-17013A

Dofequidar fumarate 2 Publications Verification MS-209	P-glycoprotein	Cancer
Dofequidar fumarate(MS-209 fumarate), an orally active quinoline compound, has been reported to overcome MDR by inhibiting ABCB1/P-gp, ABCC1/MDR-associated protein 1, or both.

HY-149518

EGFR/BRAFV600E-IN-3	EGFR Apoptosis	Others
EGFR/BRAFV600E-IN-3 is a EGFR, BRAFV600E and EGFRT790M inhibitor with IC₅₀ value of 57 nM, 68 nM and 9.70 nM. EGFR/BRAFV600E-IN-3 is an apoptotic inducer and also displays promising antioxidant activity .

HY-N9542

Dimethyl Citric acid	Others	Others
Dimethylurea/citric acid is a highly efficient deep eutectic solvent (DES). Dimethylurea/citric acid can be used as a catalyst and a green reaction medium for the synthesis of bis(indolyl)methanes, quinolines and aryl-4, 5-diphenyl-1H-imidazoles.

HY-117445

Oxazole yellow	Fluorescent Dye	Others
Oxazole yellow is a cyanine dye composed of benzoxazole and quinoline rings connected by a linker. It is almost non-luminescent in water, but its green fluorescence is significantly enhanced after intercalation in double-stranded DNA. Oxazole yellow can be used to detect cell apoptosis .

Cat. No.	Product Name

HY-L071

Alkaloids Library

545 compounds

Alkaloids are a large and complex group of cyclic compounds that contain N. About 2,000 different alkaloids have been isolated. Important alkaloids include morphine, strychnine, atropine, colchicine, ephedrine, quinine, and nicotine. Alkaloids are useful as diet ingredients, supplements, and pharmaceuticals, in medicine and in other applications in human life. They showed anti-inflammatory, anticancer, analgesics, local anesthetic and pain relief, neuropharmacologic, antimicrobial, antifungal, and many other activities. Alkaloids are also important compounds in organic synthesis for searching new semisynthetic and synthetic compounds with possibly better biological activity than parent compounds.

MCE designs a unique collection of 545 alkaloids that all come from natural products. MCE Alkaloids Library is a useful tool for drug discovery that can be used for high throughput screening (HTS) and high content screening (HCS).

Cat. No.	Product Name	Type

HY-D0290

Quinoline yellow 2SF

Dyes

Quinoline yellow 2SF is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.

HY-D0096

3-(2-Furoyl)quinoline-2-carboxaldehyde

Dyes

3-(2-Furoyl)quinoline-2-carboxaldehyde is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.

HY-D0475

C.I.Solvent yellow 176	Dyes
C.I.Solvent yellow 176 is a quinoline dye.

HY-D2095

Medical fluorophore 33	Fluorescent Dyes/Probes
Medical fluorophore 33 is a novel quinoline-isoquinoline salt. Medical fluorophore 33 exhibits a strong fluorescent signal, good microsomal stability and high biocompatibility in vivo. Medical fluorophore 33 has antitumor activity in colorectal cancer mice .

HY-149203

MQA-P

Fluorescent Dyes/Probes

MQA-P is a multifunctional near-infrared (NIR) fluorescent probe for simultaneously detecting ONOO ^-, viscosity, and polarity within mitochondria. MQA-P exhibits a remarkable turn-on response to ONOO ^- (λ_em=645 nm) and is highly sensitive to viscosity/polarity in the NIR channel with λ_em>704 nm. MQA-P exhibits excited-state intramolecular charge transfer (ESICT) feature that is highly polarity-sensitive by engineering N,N-dimethylamino as the electron donor and a quinoline cationic unit as the electron acceptor. MQA-P is used for ferroptosis or cancer diagnosis in vitro and in vivo via dual-channel images .

Cat. No.	Product Name	Type

HY-W017232

6-Methoxyquinoline

p-Quinanisole

Biochemical Assay Reagents

6-Methoxyquinoline consists of a quinoline ring system with a methoxy group attached to the sixth carbon atom. This compound occurs naturally in certain plants, such as tobacco and tea, and has been shown to have biological activities, including antioxidant, anti-inflammatory and antitumor properties. Furthermore, 6-Methoxyquinoline can be used as a building block for the synthesis of other organic compounds, especially those with potential pharmaceutical applications. Due to its ability to bind nucleic acids and proteins, it can also be used as a fluorescent probe in biochemical and biomedical research.

HY-W004855

Quinoline-6-carboxylic acid	Biochemical Assay Reagents
Quinoline-6-carboxylic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W007371

Quinoline-8-carboxylic acid	Biochemical Assay Reagents
Quinoline-8-carboxylic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research .

HY-121462

Cyanine quinoline Blue	Indicators
Cyanine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W344938

C.I. Acid yellow 3 quinoline yellow	Indicators
C.I. Acid yellow 3 is an anionic quinolinone dye that is commonly used as a food additive, but also in the cosmetic and pharmaceutical industries .

HY-W003017

5-Quinolinylboronic acid Quinolin-5-ylboronic	Biochemical Assay Reagents
Quinoline-5-boronic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W007403

6-Bromoquinoline 6-Br-quinoline	Biochemical Assay Reagents
6-Bromoquinoline is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W002011

Quinoline-2-carboxylic acid	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Quinoline-2-carboxylic acid is an endogenous metabolite.

HY-W110662

Transtorine	Alkaloids Ephedraceae Quinoline Alkaloids Plants Ephedra sinica Stapf	Bacterial
Transtorine is a quinoline alkaloid, found from Ephedra transitoria, with antibacterial activity .

HY-59208

4-Quinolinol Kynurine	Structural Classification Alkaloids Neurological Disease Classification of Application Fields Source classification Quinoline Alkaloids Endogenous metabolite Disease Research Fields Cancer	Endogenous Metabolite
4-Quinolone (Kynurine) is a quinoline derivative. Kynurine pathway modulates tryptophan metabolism and involves in neuroprotective effect. Kynurine promotes tumor cell survival and motility by suppressing antitumor immune .

HY-N9542

Dimethyl Citric acid	Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Plants Actinidiaceae Disease Research Fields Actinidia arguta (Sieb. & Zucc) Planch. ex Miq.	Others
Dimethylurea/citric acid is a highly efficient deep eutectic solvent (DES). Dimethylurea/citric acid can be used as a catalyst and a green reaction medium for the synthesis of bis(indolyl)methanes, quinolines and aryl-4, 5-diphenyl-1H-imidazoles.

HY-155704

Lyciumamide A	Structural Classification Lycium barbarum L. Source classification Phenols Polyphenols Plants Solanaceae	Others
DPP-IV-IN-5 is isolated from the fruits of Lycium barbarum. DPP-IV-IN-5 exerts moderate agonistic activities for peroxisome proliferator-activated receptor (PPARγ) with EC₅₀ values of 10.09 - 44.26 μM and also presents inhibitory activity on dipeptidyl peptidase-4 (DPPIV) with an IC₅₀ value of 47.13 μM .

HY-125060

Viridicatin	Infection Alkaloids Microorganisms Classification of Application Fields Source classification Quinoline Alkaloids Disease Research Fields	Antibiotic Endogenous Metabolite
Viridicatin is a fungal metabolite from Penicillium species. Viridicatin shows slight in vitro antibiotic activity against Mycobacterium tuberculosis .

HY-N12964

4-Hydroxycanthin-6-one	Structural Classification Alkaloids Simaroubaceae Ailanthus altissima (Mill.) Swingle Source classification Quinoline Alkaloids Plants	Others
4-Hydroxycanthin-6-one is a novel quinoline alkaloid isolated from the stem bark of the tree Ailanthus altissima. Five other known compounds were also found in the study. The structures of the new compounds were determined by interpretation of physical and spectroscopic data, and their absolute configurations were determined by electronic circular dichroism spectroscopy and quantum chemical calculations. These compounds showed significant inhibitory activity against lipopolysaccharide (LPS)-induced nitric oxide (NO) production in RAW 264.7 cells, showing potential anti-inflammatory properties .

Cat. No.	Product Name	Chemical Structure

HY-W719475

Quinoline-d7
Quinoline-d7 is the deuterium labeled Quinoline .

HY-W002011S

Quinoline-2-carboxylic acid-d6
Quinoline-2-carboxylic acid-d₆ is the deuterium labeled Quinoline-2-carboxylic acid[1]. Quinoline-2-carboxylic acid is an endogenous metabolite.

HY-116021S

Buquinolate-13C3
Buquinolate-13C3 is the ¹³C₃ labeled Buquinolate. Buquinolate is a quinoline derivative, which is developed as a coccidiostat for the prevention of coccidiosis in poultry .

Cat. No.	Product Name		Classification

HY-118197

L-669083		Azide
L-669083 is a leukotriene biosynthesis inhibitor whose structure is based on a mixture of indole and quinoline. In this study, a potent radioiodinated photoaffinity analog of L-689,037, [125I] L-691,678, was developed and characterized for immunoprecipitation studies showing that the quindole series of leukotriene biosynthesis inhibitors directly interact with FLAP. In addition, the results showed that MK-886, L-674,573, and L-689,037 competed with [125I] L-691,678 and [125I] L-669083 for binding to FLAP in a concentration-dependent manner, indicating that these three leukotriene biosynthesis inhibitors share a binding site on FLAP, further demonstrating that FLAP is a suitable target for structurally diverse leukotriene biosynthesis inhibitors.

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quinoline

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