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37

Inhibitors & Agonists

1

Biochemical Assay Reagents

2

Peptides

9

Natural
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Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W089856
    Chlorobutanol hemihydrate

    		Bacterial Fungal Infection Neurological Disease
    Chlorobutanol hemihydrate is a pharmaceutical preservative. Chlorobutanol hemihydrate is active against a wide variety of Gram-positive and Gram-negative bacteria, and several mold spores and fungi. Chlorobutanol hemihydrate is widely used in food and cosmetic industry .
    Chlorobutanol hemihydrate
  • HY-125361
    Ganosporeric acid A

    		Others Others
    Ganosporeric acid A, a natural product, is isolated from the ether-soluble fraction of the spores of Ganoderma lucidum. Ganosporeric acid A can be used for the research of liver injury .
    Ganosporeric acid A
  • HY-W001132
    Indole
    1 Publications Verification

    		 Endogenous Metabolite Infection
    Indole is an aromatic, heterocyclic, organic compound which widely distributed in the natural environment and can be produced by a variety of bacteria. Indole regulates various aspects of bacterial physiology, including spore formation, plasmid stability, resistance to drugs, biofilm formation, and virulence as an intercellular signal molecule .
    Indole
  • HY-127160
    Benzoxonium chloride

    		Parasite Bacterial Infection
    Benzoxonium chloride is an anti-leishmanial agent. Benzoxonium chloride inhibits bacteria, certain protozoa, yeasts and non-spore forming organisms .
    Benzoxonium chloride
  • HY-137159
    Bestatin methyl ester

    		Aminopeptidase Cancer
    Bestatin methyl ester is a cell permeable Zn2+-binding aminopeptidases inhibitor. Bestatin methyl ester inhibits spore cell differentiation .
    Bestatin methyl ester
  • HY-B1263R
    Chlorobutanol (Standard)

    		Bacterial Fungal Infection Neurological Disease
    Chlorobutanol (Standard) is the analytical standard of Chlorobutanol. This product is intended for research and analytical applications. Chlorobutanol is a pharmaceutical preservative. Chlorobutanol is active against a wide variety of Gram-positive and Gram-negative bacteria, and several mold spores and fungi. Chlorobutanol is widely used in food and cosmetic industry .
    Chlorobutanol (Standard)
  • HY-W089856R
    Chlorobutanol hemihydrate (Standard)

    		Bacterial Fungal Infection Neurological Disease
    Chlorobutanol (hemihydrate) (Standard) is the analytical standard of Chlorobutanol (hemihydrate). This product is intended for research and analytical applications. Chlorobutanol hemihydrate is a pharmaceutical preservative. Chlorobutanol hemihydrate is active against a wide variety of Gram-positive and Gram-negative bacteria, and several mold spores and fungi. Chlorobutanol hemihydrate is widely used in food and cosmetic industry .
    Chlorobutanol hemihydrate (Standard)
  • HY-121461
    A25822B

    15-Azasterol

    		 Fungal Infection
    A25822B is an antifungal agent, with a MIC of 1 μM for Ascosphaera apis. A25822B causes conformational changes in mitochondria and disruption of spore membrane structure. A25822B can be used for the research of bee chalk disease .
    A25822B
  • HY-129153
    Ganoderic acid ζ

    		Others Others
    Ganoderic acid ζ is a triterpene that can be isolated from the spores of Ganoderma lucidum .
    Ganoderic acid ζ
  • HY-N9128
    Medicarpin 3-O-glucoside

    		Others Others
    Medicarpin 3-O-glucoside a phytoalexin, shows inhibition against the germination of G. intraradices spores and hyphal elongation .
    Medicarpin 3-O-glucoside
  • HY-N12976
    Oryzalexin E

    		Fungal Infection
    Oryzalexin E is a diterpene phytoalexin, and can be isolated from UV-irradiated rice leaves. Oryzalexin E inhibits spore germination of Pyricularia oryzae with the ED50 of 62.5 ppm .
    Oryzalexin E
  • HY-118169
    A-Factor

    		Others Infection
    A-Factor is an inducer of streptomycin biosynthesis in an inactive mutant of Streptomyces griseus. In addition, A-Factor can also induce spore formation during conidial development of Magnaporthe oryzae .
    A-Factor
  • HY-B0850
    Difenoconazole

    		Fungal Infection
    Difenoconazole is a sterol demethylation inhibitor, as a fungicide. Difenoconazole binds the heme portion of the fungal cytochrome P450 51, interferes the mycelial growth and inhibits the spore germination of pathogens, suppressing fungal growth .
    Difenoconazole
  • HY-P5691
    P1

    		Bacterial Infection
    P1 is a broad-spectrum antimicrobial peptide. P1 shows antibacterial activity against Gram-positive and Gram-negative bacteria,such as B. anthracis spores and Carbapenem-resistant A. baumannii and K. pneumoniae .
    P1
  • HY-B0519C
    Tylosin lactate

    		Bacterial Infection
    Tylosin (lactate) is an anti-bacterial agent that can target spore-forming bacteria. Tylosin (lactate) can increase the levels of Enterococcus and lactobacilli in dogs' feces and help relieve tylosin-responsive diarrhea .
    Tylosin lactate
  • HY-135549
    Fluxapyroxad

    		Fungal Antibiotic Infection
    Fluxapyroxad is a synthetic broad-spectrum fungicide for the control of fungal diseases. It works by inhibiting succinate dehydrogenase in complex II of the mitochondrial respiratory chain, resulting in inhibition of spore germination, germ tubes and mycelia growth within the fungus target species .
    Fluxapyroxad
  • HY-N13024
    Radulone A

    		Fungal Infection
    Radulone A is a secondary metabolite, which can be isolated from the wood decomposing fungus Granulobasidium vellereum. Radulone A inhibits spore germination of Phlebiopsis gigantea, Coniophora puteana and Heterobasidion occidentale, with concentrations of 10 µM, 500 µM and 100 µM, respectively .
    Radulone A
  • HY-115440
    CRS3123 dihydrochloride

    REP-3123 dihydrochloride

    		 Bacterial Antibiotic Infection
    CRS3123 (REP-3123) dihydrochloride, a fully synthetic antibacterial agent, potently inhibits methionyl-tRNA synthetase (MetRS) of Clostridioides difficile, inhibiting Clostridioides difficile toxin production and spore formation. CRS3123 dihydrochloride is an oral agent for the research of Clostridioides difficile infection (CDI) .
    CRS3123 dihydrochloride
  • HY-B0850R
    Difenoconazole (Standard)

    		Fungal Infection
    Difenoconazole (Standard) is the analytical standard of Difenoconazole. This product is intended for research and analytical applications. Difenoconazole is a sterol demethylation inhibitor, as a fungicide. Difenoconazole binds the heme portion of the fungal cytochrome P450 51, interferes the mycelial growth and inhibits the spore germination of pathogens, suppressing fungal growth .
    Difenoconazole (Standard)
  • HY-W009274
    N-Acetylmuramic acid

    MurNAc; NAMA

    		 Endogenous Metabolite Others
    N-acetylmuramic acid is a component of the bacterial cell wall peptidoglycan, essential for maintaining cell shape and integrity . N-acetylmuramic acid inhibits spore germination by inhibiting a coat-associated hexosaminidase and a core enzyme . N-acetylmuramic acid is required by Bacteroides forsythus for proliferation and the maintenance of its cell shape .
    N-Acetylmuramic acid
  • HY-155702
    Antifungal agent 66

    		Fungal Infection
    Antifungal agent 66 (compound 10) has antifungal activity. Antifungal agent 66 has a broad-spectrum antifungal activity against seven phytopathogenic fungal mycelia. Antifungal agent 66 has pronounced inhibitory activity against the spore of B. cinerea with an IC50 value of 47.7 μg/mL .
    Antifungal agent 66
  • HY-75828
    Dibenzylideneacetone

    		Bacterial Infection
    Dibenzylideneacetone is a potent inhibitor of chitinase with an IC50 value of 13.10 μM. The MIC value of Dibenzylideneacetone against Botrytis cinerea is 32 μg/mL, and the EC50 values for inhibiting mycelium growth and spore germination are 16.29 and 14.64 μg/mL, respectively. Dibenzylideneacetone can be used in research on fruit and vegetable preservatives .
    Dibenzylideneacetone
  • HY-143454
    Germination-IN-1

    		Others Inflammation/Immunology
    Germination-IN-1 (compound 11) is a potent germination inhibitor with an IC50 of 4 µM. Germination-IN-2 shows anti-germination activity with 14% germination rate .
    Germination-IN-1
  • HY-143455
    Germination-IN-2

    		Others Inflammation/Immunology
    Germination-IN-2 (compound 15) is a potent germination inhibitor with an IC50 of 1.3 µM. Germination-IN-2 shows anti-germination activity with 3% germination rate .
    Germination-IN-2
  • HY-121387
    Furmecyclox

    		Fungal Infection
    Furmecyclox is an effective fungicide. Furmecyclox shows great effects against basidiomycetes .
    Furmecyclox
  • HY-135549R
    Fluxapyroxad (Standard)

    		Fungal Antibiotic Infection
    Fluxapyroxad (Standard) is the analytical standard of Fluxapyroxad. This product is intended for research and analytical applications. Fluxapyroxad is a synthetic broad-spectrum fungicide for the control of fungal diseases. It works by inhibiting succinate dehydrogenase in complex II of the mitochondrial respiratory chain, resulting in inhibition of spore germination, germ tubes and mycelia growth within the fungus target species .
    Fluxapyroxad (Standard)
  • HY-17518A
    (S,S)-Valifenalate

    (S,S)-IR5885; (S,S)-Valiphenal

    		 Fungal Infection
    (S,S)-Valifenalate ((S,S)-IR5885) is an acylamino acid fungicide and is used to control a wide range of fungi belonging to the class of Oomycetes. (S,S)-Valifenalate ((S,S)-IR5885) interferes with the cell-wall synthesis thus affecting the growth stages of the pathogens controlled, both outside (on the spores) or inside the plant (on the mycelium) .
    (S,S)-Valifenalate
  • HY-N2573A
    Corydalmine hydrochloride

    L-Corydalmine hydrochloride; TLZ-16-CL

    		 Fungal CXCR Infection Neurological Disease
    Corydalmine hydrochloride inhibits spore germination of some plant pathogenic as well as saprophytic fungi . Corydalmine hydrochloride acts as an oral analgesic agent, exhibiting potent analgesic activity . Corydalmine hydrochloride alleviates Vincristine-induced neuropathic pain in mice by inhibiting an NF-κB-dependent CXCL1/CXCR2 signaling pathway .
    Corydalmine hydrochloride
  • HY-23155
    2-Phenylethyl isothiocyanate

    2-PE ITC

    		 Fungal Infection
    2-Phenylethyl isothiocyanate is a potent antifungal agent. 2-Phenylethyl isothiocyanate significantly inhibited spore germination and mycelial growth of Alternaria alternata, with a MIC (minimum inhibitory concentration) of 1.22 mM. The antifungal effect of 2-Phenylethyl isothiocyanate against Alternaria alternata might be via reduction in toxin content and breakdown of cell membrane integrity .
    2-Phenylethyl isothiocyanate
  • HY-N2573
    Corydalmine

    L-Corydalmine; TLZ-16

    		 Fungal CXCR Infection Neurological Disease
    Corydalmine (L-Corydalmine) inhibits spore germination of some plant pathogenic as well as saprophytic fungi . Corydalmine acts as an oral analgesic agent, exhibiting potent analgesic activity . Corydalmine alleviates Vincristine-induced neuropathic pain in mice by inhibiting an NF-κB-dependent CXCL1/CXCR2 signaling pathway .
    Corydalmine
  • HY-129548
    Prumycin

    		Others Infection
    Prumycin is an antifungal antibiotic with activity against cucumber powdery mildew. Prumycin significantly inhibited the disease, whereas other metabolites such as bacillomycin D and surfactin did not. Prumycin did not induce the expression of plant defense genes, indicating that its effects were not through plant defense responses. Observation of cucumber cotyledons treated with prumycin showed that it could inhibit spore germination of P. fusca .
    Prumycin
  • HY-129548A
    Prumycin di(hydrochloride)

    		Others Infection
    Prumycin dihydrochloride is an antifungal antibiotic with activity against cucumber powdery mildew. Prumycin dihydrochloride significantly inhibited the disease, whereas other metabolites such as bacillomycin D and surfactin did not. Prumycin dihydrochloride did not induce the expression of plant defense genes, indicating that its effects were not through plant defense responses. Observation of cucumber cotyledons treated with prumycin showed that it could inhibit spore germination of P. fusca .
    Prumycin di(hydrochloride)
  • HY-P1939
    Cyclo(L-Leu-L-Pro)

    Cyclo(L-prolyl-L-leucyl)

    		 Fungal Infection
    Cyclo(L-Leu-L-Pro) is an inhibitory substance targeting to production of norsolorinic acid (NA，a precursor of aflatoxin)，which can be isolated from A. xylosoxidans NFRI-A1. Cyclo(L-Leu-L-Pro) inhibits accumulation of NA by A. parasiticus NFRI-95 and inhibits spore formation. Cyclo(L-Leu-L-Pro) inhibits aflatoxin production with an IC50 of 0.2 mg/mL in A. parasiticus SYS-4 .
    Cyclo(L-Leu-L-Pro)
  • HY-B1263
    Chlorobutanol

    		Bacterial Fungal Infection Neurological Disease
    Chlorobutanol is an orally active and potent inhibitor of platelet aggregation and release and a pharmaceutical preservative with antibacterial activity. Chlorobutanol inhibits thromboxane B2 formation, ATP release, and elevation of cytosolic free calcium caused by collagen, ADP, epinephrine, arachidonic acid and thrombin. Chlorobutanol is active against a wide variety of Gram-positive and Gram-negative bacteria, and several mold spores and fungi. Chlorobutanol is widely used in food and cosmetic industry .
    Chlorobutanol
  • HY-23155S
    2-Phenylethyl isothiocyanate-d5

    2-PE ITC-d5

    		 Fungal Infection
    2-Phenylethyl isothiocyanate-d5 isothiocyanate-d5 is the deuterium labeled 2-Phenylethyl isothiocyanate[1]. 2-Phenylethyl isothiocyanate is a potent antifungal agent. 2-Phenylethyl isothiocyanate significantly inhibited spore germination and mycelial growth of Alternaria alternata, with a MIC (minimum inhibitory concentration) of 1.22 mM. The antifungal effect of 2-Phenylethyl isothiocyanate against Alternaria alternata might be via reduction in toxin content and breakdown of cell membrane integrity[2][3].
    2-Phenylethyl isothiocyanate-d5
  • HY-155004
    SDH-IN-3

    		Antibiotic Fungal Infection
    SDH-IN-3 is a succinate dehydrogenase (SDH) inhibitor with an IC50 of 7.2 μg/mL. SDH-IN-3 exhibits excellent antifungal activities against Nigrospora oryzae with an EC50 of 1.9 μg/mL. SDH-IN-3 can be used for anti-infection research .
    SDH-IN-3
  • HY-136409
    N-Decanoyl-L-homoserine lactone

    C10-HSL

    		 Bacterial Reactive Oxygen Species Infection
    N-decanoyl-L-homoserine lactone (C10-HSL) is a N-acyl-homoserine lactone (AHL) N-decanoyl-L-homoserine lactone can inhibit primary root growth in Arabidopsis. N-decanoyl-L-homoserine lactone triggers a transient and immediate increase in the concentrations of cytosolic free Ca 2+ and reactive oxygen species (ROS), increases the activity of mitogen-activated protein kinase 6 (MPK6), and induces nitric oxide (NO) production in Arabidopsis roots .
    N-Decanoyl-L-homoserine lactone

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