2. Anti-infection
  3. Fungal
  4. Cyclo(L-Leu-L-Pro)

Cyclo(L-Leu-L-Pro)  (Synonyms: Cyclo(L-prolyl-L-leucyl))

Cat. No.: HY-P1939 Purity: 99.84%
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Cyclo(L-Leu-L-Pro) is an inhibitory substance targeting to production of norsolorinic acid (NA，a precursor of aflatoxin)，which can be isolated from A. xylosoxidans NFRI-A1. Cyclo(L-Leu-L-Pro) inhibits accumulation of NA by A. parasiticus NFRI-95 and inhibits spore formation. Cyclo(L-Leu-L-Pro) inhibits aflatoxin production with an IC50 of 0.2 mg/mL in A. parasiticus SYS-4.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Cyclo(L-Leu-L-Pro) Chemical Structure

Cyclo(L-Leu-L-Pro) Chemical Structure

CAS No. : 2873-36-1

Size Price Stock Quantity
5 mg USD 32 In-stock
10 mg USD 50 In-stock
25 mg USD 105 In-stock
50 mg USD 170 In-stock
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This product is a controlled substance and not for sale in your territory.

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Based on 1 publication(s) in Google Scholar

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Description

Cyclo(L-Leu-L-Pro) is an inhibitory substance targeting to production of norsolorinic acid (NA，a precursor of aflatoxin)，which can be isolated from A. xylosoxidans NFRI-A1. Cyclo(L-Leu-L-Pro) inhibits accumulation of NA by A. parasiticus NFRI-95 and inhibits spore formation. Cyclo(L-Leu-L-Pro) inhibits aflatoxin production with an IC50 of 0.2 mg/mL in A. parasiticus SYS-4[1].

Molecular Weight

210.27

Formula

C11H18N2O2
CAS No.
Appearance

Solid

Color

White to off-white

Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture and light, under nitrogen

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (1188.95 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.7558 mL 23.7789 mL 47.5579 mL
5 mM 0.9512 mL 4.7558 mL 9.5116 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.7558 mL 23.7790 mL 47.5579 mL 118.8948 mL
5 mM 0.9512 mL 4.7558 mL 9.5116 mL 23.7790 mL
10 mM 0.4756 mL 2.3779 mL 4.7558 mL 11.8895 mL
15 mM 0.3171 mL 1.5853 mL 3.1705 mL 7.9263 mL
20 mM 0.2378 mL 1.1889 mL 2.3779 mL 5.9447 mL
25 mM 0.1902 mL 0.9512 mL 1.9023 mL 4.7558 mL
30 mM 0.1585 mL 0.7926 mL 1.5853 mL 3.9632 mL
40 mM 0.1189 mL 0.5945 mL 1.1889 mL 2.9724 mL
50 mM 0.0951 mL 0.4756 mL 0.9512 mL 2.3779 mL
60 mM 0.0793 mL 0.3963 mL 0.7926 mL 1.9816 mL
80 mM 0.0594 mL 0.2972 mL 0.5945 mL 1.4862 mL
100 mM 0.0476 mL 0.2378 mL 0.4756 mL 1.1889 mL
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Cyclo(L-Leu-L-Pro) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cyclo(L-Leu-L-Pro)2873-36-1Cyclo(L-prolyl-L-leucyl)FungalInhibitorinhibitorinhibit

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