Antifungal agent 66

Cat. No.: HY-155702: FAQs
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Antifungal agent 66 (compound 10) has antifungal activity. Antifungal agent 66 has a broad-spectrum antifungal activity against seven phytopathogenic fungal mycelia. Antifungal agent 66 has pronounced inhibitory activity against the spore of B. cinerea with an IC₅₀ value of 47.7 μg/mL.

For research use only. We do not sell to patients.

Antifungal agent 66 Chemical Structure

CAS No. : 1613152-33-2

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Biological Activity
Purity & Documentation
References
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Description

Cellular Effect

Cell Line	Type	Value	Description	References
HCT-116	IC₅₀	18.8 μM Compound: 2	Cytotoxicity against human HCT116 cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay Cytotoxicity against human HCT116 cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay	10.1039/C4MD00209A
HeLa	IC₅₀	28.5 μM Compound: 2	Cytotoxicity against human HeLa cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay Cytotoxicity against human HeLa cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay	10.1039/C4MD00209A
SGC-7901	IC₅₀	26.5 μM Compound: 2	Cytotoxicity against human SGC7901 cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay Cytotoxicity against human SGC7901 cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay	10.1039/C4MD00209A

Molecular Weight

384.85

Formula

C₁₉H₂₅ClO₆

CAS No.

1613152-33-2

SMILES

ClCC(O[C@H]1[C@H]2[C@H](OC(C2=C)=O)CC(C)=C1[C@@H](C)CCCOC(C)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Zhi XY, et, al. Discovery of Natural Sesquiterpene Lactone 1-O-Acetylbritannilactone Analogues Bearing Oxadiazole, Triazole, or Imidazole Scaffolds for the Development of New Fungicidal Candidates. J Agric Food Chem. 2023 Aug 2;71(30):11680-11691. [Content Brief]