2. Metabolic Enzyme/Protease
  3. Aminopeptidase
  4. Bestatin methyl ester

Bestatin methyl ester is a cell permeable Zn2+-binding aminopeptidases inhibitor. Bestatin methyl ester inhibits spore cell differentiation.

For research use only. We do not sell to patients.

Bestatin methyl ester Chemical Structure

Bestatin methyl ester Chemical Structure

CAS No. : 65322-89-6

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Bestatin methyl ester Related Antibodies

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Description

Bestatin methyl ester is a cell permeable Zn2+-binding aminopeptidases inhibitor. Bestatin methyl ester inhibits spore cell differentiation[1].

Cellular Effect
Cell Line Type Value Description References
HT-1080 IC50
0.69 μM
Compound: 2, MeBS
Degradation promoting activity of FLAG tagged cIAP1 expressed in human HT1080 cells after 3 hrs by Western blotting analysis
Degradation promoting activity of FLAG tagged cIAP1 expressed in human HT1080 cells after 3 hrs by Western blotting analysis
[PMID: 18448338]
HT-1080 IC50
0.69 μM
Compound: 2, MeBS
Promotion of flag-tagged cIAP1 degradation in human HT1080 cells assessed as decrease in cIAPI production after 3 hrs
Promotion of flag-tagged cIAP1 degradation in human HT1080 cells assessed as decrease in cIAPI production after 3 hrs
[PMID: 18313309]
In Vitro

Bestatin methyl ester (600, 900 µM; 24 h) inhibits spore cell differentiation in Dictyostelium discoideum[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Bestatin methyl ester Related Antibodies
Molecular Weight

322.40

Formula

C17H26N2O4
CAS No.
SMILES

CC(C)C[C@@H](C(OC)=O)NC([C@@H](O)[C@H](N)CC1=CC=CC=C1)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Bestatin methyl ester Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Bestatin methyl ester65322-89-6Aminopeptidasecell permeableDictyostelium discoideumsporeInhibitorinhibitorinhibit

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Bestatin methyl ester
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HY-137159
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