N-Acetylmuramic acid (Synonyms: MurNAc; NAMA)

Cat. No.: HY-W009274 Purity: ≥99.0%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

N-acetylmuramic acid is a component of the bacterial cell wall peptidoglycan, essential for maintaining cell shape and integrity. N-acetylmuramic acid inhibits spore germination by inhibiting a coat-associated hexosaminidase and a core enzyme. N-acetylmuramic acid is required by Bacteroides forsythus for proliferation and the maintenance of its cell shape.

For research use only. We do not sell to patients.

N-Acetylmuramic acid Chemical Structure

CAS No. : 10597-89-4

Size	Price	Stock	Quantity
5 mg	USD 50	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 75	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

or Bulk Inquiry

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Featured Recommendations

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

Biological Activity
Purity & Documentation
References
Customer Review

Description

N-acetylmuramic acid is a component of the bacterial cell wall peptidoglycan, essential for maintaining cell shape and integrity^[1]. N-acetylmuramic acid inhibits spore germination by inhibiting a coat-associated hexosaminidase and a core enzyme^[2]. N-acetylmuramic acid is required by Bacteroides forsythus for proliferation and the maintenance of its cell shape^[3].

IC₅₀ & Target

Human Endogenous Metabolite

Molecular Weight

293.27

Formula

C₁₁H₁₉NO₈

CAS No.

10597-89-4

Appearance

Solid

Color

White to off-white

SMILES

CC(N[C@@H](C=O)[C@@H](O[C@H](C)C(O)=O)[C@H](O)[C@H](O)CO)=O

Structure Classification

Others

Initial Source

Endogenous metabolite

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Solvent & Solubility

In Vitro:

H₂O : 100 mg/mL (340.98 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.4098 mL	17.0491 mL	34.0983 mL
5 mM	0.6820 mL	3.4098 mL	6.8197 mL
10 mM	0.3410 mL	1.7049 mL	3.4098 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: ≥99.0%

Select Batch:

Data Sheet (274 KB) SDS (557 KB)

COA (252 KB)

Handling Instructions (2659 KB)

References

[1]. Herbold DR, Glaser L. Interaction of N-acetylmuramic acid L-alanine amidase with cell wall polymers. J Biol Chem. 1975 Sep 25;250(18):7231-8 [Content Brief]

[2]. Brown W, et al. N-acetylmuramic acid inhibits spore germination and germination enzymes. J Basic Microbiol. 1990;30(2):67-72 [Content Brief]

[3]. Wyss C. Dependence of proliferation of Bacteroides forsythus on exogenous N-acetylmuramic acid. Infect Immun. 1989 Jun;57(6):1757-9 [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	3.4098 mL	17.0491 mL	34.0983 mL	85.2457 mL
	5 mM	0.6820 mL	3.4098 mL	6.8197 mL	17.0491 mL
	10 mM	0.3410 mL	1.7049 mL	3.4098 mL	8.5246 mL
	15 mM	0.2273 mL	1.1366 mL	2.2732 mL	5.6830 mL
	20 mM	0.1705 mL	0.8525 mL	1.7049 mL	4.2623 mL
	25 mM	0.1364 mL	0.6820 mL	1.3639 mL	3.4098 mL
	30 mM	0.1137 mL	0.5683 mL	1.1366 mL	2.8415 mL
	40 mM	0.0852 mL	0.4262 mL	0.8525 mL	2.1311 mL
	50 mM	0.0682 mL	0.3410 mL	0.6820 mL	1.7049 mL
	60 mM	0.0568 mL	0.2842 mL	0.5683 mL	1.4208 mL
	80 mM	0.0426 mL	0.2131 mL	0.4262 mL	1.0656 mL
	100 mM	0.0341 mL	0.1705 mL	0.3410 mL	0.8525 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

N-Acetylmuramic acid Related Classifications

Others

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

N-Acetylmuramic acid10597-89-4MurNAc NAMAEndogenous MetabolitePeptidoglycan Synthesis:Enzyme TargetsBacterial GrowthInhibitorinhibitorinhibit

Your Recently Viewed Products:

Product Name

Salutation

Applicant Name *

Email Address *

Phone Number *

Organization Name *

Department *

Requested quantity *

Country or Region *

Remarks