Tauro-α-muricholic acid  (Synonyms: T-α-MCA)

Tauro-alpha-muricholic acid (T-alpha-MCA) is a bile acid that belongs to a class of compounds that are synthesized in the liver and play an important role in the digestive process. Tauro-α-muricholic acid activates Farni X receptors (FXR) which are involved in the regulation of bile acid synthesis, metabolism and transport. Tauro-alpha-muricholic acid can be used in the study of metabolic syndrome and cardiovascular disease^[1].

515.70

C₂₆H₄₅NO₇S

25613-05-2

C[C@@H]([C@H]1CC[C@]2([C@@]3([C@@H]([C@H]([C@@]4(C[C@@H](CC[C@@]4([C@]3(CC[C@]12C)[H])C)O)[H])O)O)[H])[H])CCC(NCCS(=O)(O)=O)=O

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. FUJIHIRA E, et al. A new solvent system for thin-layer chromatographical separation of taurine-conjugated trihydroxy bile acids in rat bile[J]. Chemical and Pharmaceutical Bulletin, 1972, 20(12): 2719-2721.  [Content Brief]