Endogenous Metabolite

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Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Endogenous Metabolite Related Products (7416)
Antibodies (477)

By Effects:	Controls (3) Inhibitors (31) Agonist (1) Antagonist (1) Activators (2) Modulators (8) Chemicals (2) Inducers (6)

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-75087S

(R)-Pyrrolidine-2-carboxylic acid-d₃
(R)-Pyrrolidine-2-carboxylic acid-d₃ is the deuterium labeled (R)-pyrrolidine-2-carboxylic acid. (R)-pyrrolidine-2-carboxylic acid is an endogenous metabolite.

HY-125628

Kahalalide A
Kahalalide A is an anti-mycobacterial compound with antimicrobial activity. Kahalalide A is derived from the marine mollusk Elysia rufescens. Kahalalide A has attracted extensive attention in natural product research due to its potential medicinal value.

HY-113126A

3-Hydroxyisobutyric acid sodium
3-Hydroxyisobutyric acid sodium is an important interorgan metabolite, an intermediate in the pathways of l-valine and thymine and a good gluconeogenic substrate.

HY-W016009S3

2'-Deoxyadenosine-5'-monophosphate-¹³C₁₀ dilithium
2'-Deoxyadenosine-5'-monophosphate-¹³C₁₀ dilithium is ¹³C-labeled 2'-Deoxyadenosine-5'-monophosphate (HY-W016009). 2′-Deoxyadenosine 5′-monophosphate, a nucleic acid AMP derivative, is a deoxyribonucleotide found in DNA. 2′-Deoxyadenosine 5′-monophosphate can be used to study adenosine-based interactions during DNA synthesis and DNA damage.

HY-W018772S

D-Ribose-¹⁸O
D-Ribose-¹⁸O is the ¹⁸O labeled D-Ribose. D-Ribose is an energy enhancer, and acts as a sugar moiety of ATP, and widely used as a metabolic therapy supplement for chronic fatigue syndrome or cardiac energy metabolism. D-Ribose is active in protein glycati

HY-110189S1

Pregnenolone monosulfate-d₄ sodium
Pregnenolone monosulfate-d₄ (sodium) is the deuterium labeled Pregnenolone monosulfate. Pregnenolone monosulfate sodium (3β-Hydroxy-5-pregnen-20-one monosulfate sodium) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone monosulfate sodium acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone monosulfate sodium can protect the brain from cannabis intoxication[1][2]. Pregnenolone monosulfate sodium is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels[3].

HY-N0379S19

D-Mannose-d-4
D-Mannose-d-4 is the deuterium labeled D-Mannose. D-Mannose is a carbohydrate, which plays an important role in human metabolism, especially in the glycosylationof specific prote[1][2].

HY-W010452S

3-Hydroxybutyric acid-d₂ sodium
3-Hydroxybutyric acid-d₂ (sodium) is the deuterium labeled 3-Hydroxybutyric acid sodium[1]. 3-Hydroxybutyric acid sodium (β-Hydroxybutyric acid sodium) is a metabolite that is elevated in type I diabetes. 3-Hydroxybutyric acid sodium can modulate the properties of membrane lipids[2].

HY-D0186S3

2'-Deoxyuridine-5′-¹³C
2'-Deoxyuridine-5′-¹³C is the ¹³C labeled 2'-Deoxyuridine. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. A known use of 2'-Deoxyuridine is as a precursor in the synthesis of Edoxud[1]

HY-112530S

1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine-d₇₀
1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine-d₇₀ is deuterium labeled 1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine. 1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine (DSPE) is a phosphoethanolamine (PE) lipid that can be used in the synthesis

HY-N0684S1

Vitamin K1-d₄
Vitamin K1-d₄ is the deuterium labeled Vitamin K1. Vitamin K1 a naturally occurring vitamin required for blood coagulation and bone and vascular metabolism[1].

HY-A0115R

Ramiprilat (Standard)
Alvimopan (dihydrate) (Standard) is the analytical standard of Alvimopan (dihydrate). This product is intended for research and analytical applications. Alvimopan dihydrate (ADL 8-2698 dihydrate) is a potent, selective, orally active and reversible μ-opioid receptor antagonist, with an IC50 of 1.7 nM. Alvimopan dihydrate has selectivity for μ-opioid receptor (Ki=0.47 nM) over κ- and δ-opioid receptors (Kis=100, 12 nM, respectively). Alvimopan dihydrate can be used for the research of postoperative ileus.

HY-128417S1

Alpha-D-glucose-¹³C
Alpha-D-glucose-¹³C is the ¹³C labeled alpha-D-glucose. alpha-D-glucose is an endogenous metabolite[1].

HY-Y1644R

NSC 8751 (Standard)

HY-P2802B

α-Glucosidase, rice
α-Glucosidase, rice is a carbohydrase enzyme that catalyzes the release of α-glucose molecules. α-Glucosidase, rice retains exoglycosidases, which hydrolyze α-glucosidic linkage at the nonreducing end of a substrate.

HY-B1659AS

D-Glycerol-3-¹³C
D-Glycerol-3-¹³C is the ¹³C labeled D-Glycerol[1].

HY-N0469S

L-Lysine-d₃ hydrochloride
L-Lysine-d₃ (hydrochloride) is the deuterium labeled L-Lysine. L-lysine is an essential amino acid[1][2] with important roles in connective tissues and carnitine synthesis, energy production, growth in children, and maintenance of immune functions[2].

HY-135880A

OMDM-4
OMDM-4 is a selective and metabolically stable inhibitor of anandamide cellular uptake (ACU), with a K_i 17.7 μM.

HY-W040329S3

2'-Deoxyadenosine-¹⁵N₅,d₁₃
2'-Deoxyadenosine-¹⁵N₅,d₁₃ is deuterium and ¹⁵N labeled 2'-Deoxyadenosine (HY-W040329). 2'-Deoxyadenosine is a nucleoside adenosine derivative, pairing with deoxythymidine (T) in double-stranded DNA.

HY-P10296

p60 (217–225)
p60 (217–225) is the subdominant epitope of Listeria monocytogenes, which combines with H-2K^d MHC class I molecules.

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Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite Related Products (7416)

Antibodies (477)

Endogenous Metabolite Related Products (7416):