2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

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Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-118915
    FR 106969
    FR 106969 (A26771E) is a platelet activating factor antagonist with anti-inflammatory activity. FR 106969 can be used to alleviate inflammatory responses. FR 106969 has shown potential inhibitory effects on inflammation-related diseases in studies.
    FR 106969
  • HY-Y0921S
    (±)-1,2-Propanediol-d8
    (±)-1,2-Propanediol-d8 is the deuterium labeled (±)-1,2-Propanediol. (±)-1,2-Propanediol (1,2-(RS)-Propanediol) is an aliphatic alcohol and frequently used as an excipient in many agent formulations to increase the solubility and stability of agents.
    (±)-1,2-Propanediol-d<sub>8</sub>
  • HY-W013378S2
    Carbamazepine 10,11-epoxide-13C,d2
    Carbamazepine 10,11-epoxide-13C,d2 is the deuterium labeled Carbamazepine 10,11-epoxide-C13. Carbamazepine 10,11-epoxide-C13 is a 13C-labled Carbamazepine 10,11-epoxide. Carbamazepine 10,11-epoxide is an orally active metabolite of Carbamazepine (HY-B0246). Carbamazepine has anticonvulsant effect. Carbamazepine can be used for the research of seizures[1][2].
    Carbamazepine 10,11-epoxide-<sup>13</sup>C,d<sub>2</sub>
  • HY-101480A
    Xylamidine tosylate
    Xylamidine tosylate is a serotonin inhibitor with reproductive activity. Xylamidine tosylate can affect reproductive processes and may be used as an experimental tool in related research. The mechanism of action of Xylamidine tosylate involves the regulation of the serotonin system.
    Xylamidine tosylate
  • HY-E70256
    12:0 Coenzyme A
    12:0 Coenzyme A (Lauroyl coenzyme A triammonium) is an intermediary in fatty acid synthesis or metabolism, formed by combining long-chain fatty acids (or lauric acid) with coenzyme A. 12:0 Coenzyme A is involved in lipid biosynthesis and fatty acid transport, in which coenzyme A acts as a transport molecule to help move and target specific compounds.
    12:0 Coenzyme A
  • HY-E70324
    AMK218
    AMK218 (Immobilized amoxicillin acylase) is a biocatalyst and a key enzyme in new biocatalyst technology. Enzyme engineering focuses on enhancing enzyme reaction kinetics, substrate selectivity, and activity under harsh conditions such as low or high pH. By introducing stimulus responsiveness to these enzyme modifications, dynamic control of activity is also possible.
    AMK218
  • HY-P2588
    Osteocalcin (human)
    Osteocalcin (human) is a vitamin K-dependent bone specific protein. Osteocalcin (human) is chemotactic for several of the cell types frequently found at bone remodeling surfaces.
    Osteocalcin (human)
  • HY-W749641
    (7Z,9E)-Dodecadienyl acetate
    (7Z,9E)-Dodecadienyl acetate is a female pheromone isolated from female grapevine moths.
    (7Z,9E)-Dodecadienyl acetate
  • HY-W004260B
    Dieicosanoin
    Dieicosanoin is a diacylglycerol containing arachidic acid (HY-W004260). Arachidic acid is a saturated long-chain fatty acid with a 20-carbon backbone. Arachidic acid can be isolated from peanut butter and anaerobic fungi.
    Dieicosanoin
  • HY-N0455AS4
    L-Arginine-13C6,15N4,d7 hydrochloride
    L-Arginine-13C6,15N4,d7 (hydrochloride) is the deuterium, 13C-, and 15-labeled L-Arginine hydrochloride. L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.
    L-Arginine-<sup>13</sup>C<sub>6</sub>,<sup>15</sup>N<sub>4</sub>,d<sub>7</sub> hydrochloride
  • HY-N10228
    Gliorosein
    Gliorosein is a fungal metabolite isolated from Gliocladium. Gliorosein is isomeric with the quinol but shows a different ultraviolet absorption spectrum.
    Gliorosein
  • HY-B0400S7
    D-Sorbitol-d-2
    D-Sorbitol-d-2 is the deuterium labeled D-Sorbitol. D-Sorbitol (Sorbitol) is a six-carbon sugar alcohol and can used as a sugar substitute. D-Sorbitol can be used as a stabilizing excipient and/or isotonicity agent, sweetener, humectant, thickener and di
    D-Sorbitol-d-2
  • HY-N7718
    (−)-Rugulosin
    (−)-Rugulosin is a fungal metabolite and an orally active anti-influenzal agent.
    (−)-Rugulosin
  • HY-129099
    N-Desmethyltamoxifen
    N-Desmethyltamoxifen is the major metabolite of tamoxifen in humans. N-Desmethyltamoxifen, a poor antiestrogen, is a ten-fold more potent protein kinase C (PKC) inhibitor than Tamoxifen. N-Desmethyltamoxifen is also a potent regulator of ceramide metabolism in human AML cells, limiting ceramide glycosylation, hydrolysis, and sphingosine phosphorylation.
    N-Desmethyltamoxifen
  • HY-N0667S1
    L-Asparagine-15N2,d8
    L-Asparagine-15N2,d8 is the 15N- and deuterium labeled L-Asparagine. L-Asparagine ((-)-Asparagine) is a non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue.
    L-Asparagine-<sup>15</sup>N<sub>2</sub>,d<sub>8</sub>
  • HY-136648
    2'-Deoxyadenosine-5'-triphosphate
    2'-Deoxyadenosine-5'-triphosphate (dATP) is a nucleotide used in cells for DNA synthesis (or replication), as a substrate of DNA polymerase.
    2'-Deoxyadenosine-5'-triphosphate
  • HY-W674036
    11-Mercaptoundecylphosphoric acid
    11-Mercaptoundecylphosphoric acid is a phosphate compound with good biocompatibility and anti-cell adhesion activity. 11-Mercaptoundecylphosphoric acid can be used to construct surface modification of biomaterials and improve its application potential in the biomedical field. By adjusting its concentration and application method, 11-Mercaptoundecylphosphoric acid can effectively control the behavior and function of cells.
    11-Mercaptoundecylphosphoric acid
  • HY-129824
    3-Methyl orsellinic acid
    3-Methyl orsellinic acid is the fungal metabolite. 3-Methyl orsellinic acid can be used for synthesis of tripodalsporormielones AeC, and exhibits potential in researches related to memory and cognition.
    3-Methyl orsellinic acid
  • HY-114930
    Endopeptidase-IN-1
    Endopeptidase-IN-1 serves as an inhibitor of endopeptidase activity.
    Endopeptidase-IN-1
  • HY-N0092S3
    Inosine-13C10,15N4
    Inosine-13C10,15N4 is 13C and 15N labeled Inosine (HY-N0092). Inosine is an endogenous purine nucleoside produced by catabolism of adenosine. Inosine has anti-inflammatory, antinociceptive, immunomodulatory and neuroprotective effects. Inosine is an agonist for adenosine A1 (A1R) and A2A (A2AR) receptors.
    Inosine-<sup>13</sup>C<sub>10</sub>,<sup>15</sup>N<sub>4</sub>
Cat. No. Product Name / Synonyms Application Reactivity