2. Signaling Pathways
  3. Immunology/Inflammation
  4. DOCK
  5. DOCK2 Isoform
  6. DOCK2 Inhibitor

DOCK2 Inhibitor

DOCK2 Inhibitors (2):

Cat. No. Product Name Effect Purity
  • HY-153128
    DOCK2-IN-1
    		Inhibitor
    DOCK2-IN-1 (compound 3), a CPYPP (HY-110100) analogue, is an inhibitor of DOCK2 as well (IC50=19.1 μM). DOCK2-IN-1 binds to DOCK2 DHR-2 domain in a reversible manner to inhibits its catalytic activity. DOCK2-IN-1 blocks the activation of both chemokine receptor- and antigen receptor-mediated Rac in lymphocytes. DOCK2-IN-1 significantly suppresses chemotactic response and T cell activation.
  • HY-111355
    Cholesterol sulfate
    		Inhibitor
    Cholesterol sulfate is a DOCK2 inhibitor. Cholesterol sulfate has an IC50 value of 2 μM for mouse DOCK2. Cholesterol sulfate can be used in studies such as immunity and inflammation.