2. Metabolic Enzyme/Protease Anti-infection
  3. Cytochrome P450 Bacterial
  4. Antibacterial agent 132

Antibacterial agent 132 has anticandidal effects against C. parapsilosis (ATCC 22019) and C. krusei (ATCC 6258) with MIC90 values of <0.06 μg/mL and 62.50 μg/mL, respectively. Antibacterial agent 132 inhibits aromatase enzyme with an IC50 of 0.047μM.

For research use only. We do not sell to patients.

Antibacterial agent 132 Chemical Structure

Antibacterial agent 132 Chemical Structure

CAS No. : 3026790-18-8

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Antibacterial agent 132 Related Antibodies

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View All Isoforms
CYP1 CYP2 CYP3 CYP4 CYP11 CYP17 Aromatase/CYP19A1 CYP26 CYP51 CYP1A2 CYP2D6 CYP2C9 CYP2C19 CYP3A4 CYP17A1

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Description

Antibacterial agent 132 has anticandidal effects against C. parapsilosis (ATCC 22019) and C. krusei (ATCC 6258) with MIC90 values of <0.06 μg/mL and 62.50 μg/mL, respectively. Antibacterial agent 132 inhibits aromatase enzyme with an IC50 of 0.047μM[1].

IC50 & Target

Aromatase

 

In Vitro

Antibacterial agent 132 (compound 4j) has the cytotoxicity against NIH/3T3 healthy cell line (IC50=10 μM)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Antibacterial agent 132 Related Antibodies
Molecular Weight

412.87

Formula

C20H14ClFN4OS
CAS No.
SMILES

COC1=CC=C2N=C(C(/C=N/NC3=NC(C4=CC=CC(F)=C4)=CS3)=CC2=C1)Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Antibacterial agent 132 Related Classifications

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antibacterial agent 1323026790-18-8Antibacterial agent132Antibacterial agent-132Cytochrome P450BacterialCYPsAnticandidalC. parapsilosisC. kruseiaromatase enzymeNIH/3T3Inhibitorinhibitorinhibit

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Antibacterial agent 132
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HY-152250
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