2. Metabolic Enzyme/Protease Anti-infection
  3. Cytochrome P450 Bacterial
  4. Antibacterial agent 132

Antibacterial agent 132 has anticandidal effects against C. parapsilosis (ATCC 22019) and C. krusei (ATCC 6258) with MIC90 values of <0.06 μg/mL and 62.50 μg/mL, respectively. Antibacterial agent 132 inhibits aromatase enzyme with an IC50 of 0.047μM.

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Antibacterial agent 132 Chemical Structure

Antibacterial agent 132 Chemical Structure

CAS No. : 3026790-18-8

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Antibacterial agent 132 Related Antibodies

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CYP1 CYP2 CYP3 CYP4 CYP11 CYP17 Aromatase/CYP19A1 CYP26 CYP51 CYP2D6 CYP2C9 CYP2C19 CYP3A4 CYP17A1

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Description

Antibacterial agent 132 has anticandidal effects against C. parapsilosis (ATCC 22019) and C. krusei (ATCC 6258) with MIC90 values of <0.06 μg/mL and 62.50 μg/mL, respectively. Antibacterial agent 132 inhibits aromatase enzyme with an IC50 of 0.047μM[1].

IC50 & Target

Aromatase

 

In Vitro

Antibacterial agent 132 (compound 4j) has the cytotoxicity against NIH/3T3 healthy cell line (IC50=10 μM)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Antibacterial agent 132 Related Antibodies
Molecular Weight

412.87

Formula

C20H14ClFN4OS
CAS No.
SMILES

COC1=CC=C2N=C(C(/C=N/NC3=NC(C4=CC=CC(F)=C4)=CS3)=CC2=C1)Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Antibacterial agent 132 Related Classifications

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antibacterial agent 1323026790-18-8Antibacterial agent132Antibacterial agent-132Cytochrome P450BacterialCYPsAnticandidalC. parapsilosisC. kruseiaromatase enzymeNIH/3T3Inhibitorinhibitorinhibit

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Antibacterial agent 132
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