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  3. AzGGK TFA

AzGGK TFA is an unnatural amino acid. AzGGK TFA is site-specifically incorporated into proteins via genetic-code expansion. AzGGK TFA can be used as a site-specific probe for ubiquitylation and SUMOylation. AzGGK TFA is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

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AzGGK TFA Chemical Structure

AzGGK TFA Chemical Structure

Size Price Stock Quantity
5 mg USD 110 In-stock
10 mg USD 175 In-stock
25 mg USD 320 In-stock
50 mg USD 480 In-stock
100 mg USD 720 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of AzGGK TFA:

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Description

AzGGK TFA is an unnatural amino acid. AzGGK TFA is site-specifically incorporated into proteins via genetic-code expansion. AzGGK TFA can be used as a site-specific probe for ubiquitylation and SUMOylation. AzGGK TFA is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups[1].

Molecular Weight

400.31

Formula

C12H19F3N6O6

Appearance

Solid

SMILES

[N-]=[N+]=NCC(NCC(NCCCC[C@H](N)C(O)=O)=O)=O.OC(C(F)(F)F)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (312.26 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4981 mL 12.4903 mL 24.9806 mL
5 mM 0.4996 mL 2.4981 mL 4.9961 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.4981 mL 12.4903 mL 24.9806 mL 62.4516 mL
5 mM 0.4996 mL 2.4981 mL 4.9961 mL 12.4903 mL
10 mM 0.2498 mL 1.2490 mL 2.4981 mL 6.2452 mL
15 mM 0.1665 mL 0.8327 mL 1.6654 mL 4.1634 mL
20 mM 0.1249 mL 0.6245 mL 1.2490 mL 3.1226 mL
25 mM 0.0999 mL 0.4996 mL 0.9992 mL 2.4981 mL
30 mM 0.0833 mL 0.4163 mL 0.8327 mL 2.0817 mL
40 mM 0.0625 mL 0.3123 mL 0.6245 mL 1.5613 mL
50 mM 0.0500 mL 0.2498 mL 0.4996 mL 1.2490 mL
60 mM 0.0416 mL 0.2082 mL 0.4163 mL 1.0409 mL
80 mM 0.0312 mL 0.1561 mL 0.3123 mL 0.7806 mL
100 mM 0.0250 mL 0.1249 mL 0.2498 mL 0.6245 mL
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AzGGK TFA Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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AzGGK TFA
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HY-148835A
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