2. Vitamin D Related/Nuclear Receptor
  3. Estrogen Receptor/ERR
  4. ERRα antagonist-2

ERRα antagonist-2 (Compound 11) is a potential ERRα (estrogen related receptor α) inverse agonist with an IC50 of 0.80 μM. ERRα antagonist-2 suppresses the migration and invasion of the ER-negative MDA-MB-231 cell line. ERRα antagonist-2 inhibits breast cancer growth in vivo.

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ERRα antagonist-2 Chemical Structure

ERRα antagonist-2 Chemical Structure

CAS No. : 3032965-02-6

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ERRα antagonist-2 Related Antibodies

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Estrogen receptor ERα ERβ ERRα ERRβ ERRγ

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Description

ERRα antagonist-2 (Compound 11) is a potential ERRα (estrogen related receptor α) inverse agonist with an IC50 of 0.80 μM. ERRα antagonist-2 suppresses the migration and invasion of the ER-negative MDA-MB-231 cell line. ERRα antagonist-2 inhibits breast cancer growth in vivo[1].

IC50 & Target

ERRα

0.80 μM (IC50)

Molecular Weight

400.41

Formula

C19H16N2O6S
CAS No.
SMILES

COC1=CC=C(C=C1)OC2=CC=CC=C2NS(=O)(C3=CC=C([N+]([O-])=O)C=C3)=O
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Room temperature in continental US; may vary elsewhere.
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Purity & Documentation
References
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ERRα antagonist-2 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ERRα antagonist-23032965-02-6ERRα antagonist2ERRα antagonist 2Estrogen Receptor/ERRMDA-MB-231MCF-7HCC-1937inverse agonistbreast cancerInhibitorinhibitorinhibit

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ERRα antagonist-2
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