LRIG3 - leucine rich repeats and immunoglobulin like domains 3 Gene

Homo sapiens

Also known as LIG3

Gene ID: 121227 | Gene type: protein coding

About LRIG3

Cytogenetic location: 12q14.1 Genomic coordinates (GRCh38): 12:58,872,155-58,920,504 (from NCBI)

This gene has 9 transcripts (splice variants), 209 orthologues, 22 paralogues and is associated with 69 phenotypes. Broad expression in thyroid (RPKM 16.5), skin (RPKM 7.2) and 24 other tissues.

Summary

Predicted to act upstream of or within otolith morphogenesis. Located in extracellular space. [provided by Alliance of Genome Resources, Apr 2022]

LRIG3 Products(2)

mRNA	Protein	Name
NM_001136051.3	NP_001129523.1	leucine-rich repeats and immunoglobulin-like domains protein 3 isoform 1 precursor
NM_153377.5	NP_700356.2	leucine-rich repeats and immunoglobulin-like domains protein 3 isoform 2 precursor

LRIG3 Protein Structure

LRR_4

LRR_8

I-set

0
200
400
600
800
1000
1119 a.a.

Protein Preferred Names

Protein Names

leucine-rich repeats and immunoglobulin-like domains protein 3

LIG-3

Related Diseases

Diseases

Alias

Urofacial Syndrome 1

Urofacial Syndrome	Ochoa Syndrome
Hydronephrosis With Peculiar Facial Expression	Ufs
Inverted Smile And Occult Neuropathic Bladder	Partial Facial Palsy With Urinary Abnormalities
UFS1	Urofacial Ochoa'S Syndrome
Urofacial Syndrome Type 1	Facial Palsy, Partial, With Urinary Abnormalities
Hydronephrosis-Inverted Smile	Inverted Smile-Neurogenic Bladder
Hydronephrosis-Inverted Smile Syndrome	Inverted Smile-Neurogenic Bladder Syndrome
Partial Facial Palsy Partial With Urinary Abnormalities	Urologic Diseases

Charcot-Marie-Tooth Disease

Cmt	Hmsn
Hereditary Motor And Sensory Neuropathy	Pma
Cmt - Charcot-Marie-Tooth Disease	Charcot Marie Tooth Disease
Charcot-Marie-Tooth Hereditary Neuropathy	Charcot-Marie-Tooth Syndrome
Peroneal Muscular Atrophy	Hereditary Motor And Sensory Neuropathies

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07789	LRIG3 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	LRIG3	VGNC	VGNC:63282
Bos taurus	LRIG3	VGNC	VGNC:30984
Macaca mulatta	LRIG3	VGNC	VGNC:100073
Mus musculus	LRIG3	MGD	MGI:2443955
Rattus norvegicus	LRIG3	RGD	RGD:1561255
Canis familiaris	LRIG3	VGNC	VGNC:42769

Name
Email *

	Sorry, but the email address you supplied was invalid.