2. Gene
  3. Casp7 - caspase 7 Gene

Casp7 - caspase 7 Gene

  • Gene
  • Agent
  • Ortholog
Mus musculus

Also known as Mch3; CMH-1; mCASP-7; ICE-IAP3; caspase-7

Gene ID: 12369 | Gene type: protein coding

About Casp7

Chromosome 19: 56,385,561-56,430,776 forward strand.GRCm39:CM001012.3

This gene has 6 transcripts (splice variants), 218 orthologues, 11 paralogues and is associated with 1 phenotype.

Summary

Enables aspartic-type endopeptidase activity and cysteine-type endopeptidase activity involved in apoptotic process. Acts upstream of or within several processes, including execution phase of apoptosis; neuron apoptotic process; and response to UV. Predicted to be located in cytosol and nucleus. Predicted to be active in cytoplasm. Is expressed in brain; foregut; sensory organ; and urinary system. Human ortholog(s) of this gene implicated in Alzheimer's disease; breast cancer; colon cancer; and lung non-small cell carcinoma. Orthologous to human CASP7 (Caspase 7). [provided by Alliance of Genome Resources, Apr 2022]

Casp7 Products(1)

mRNA Protein Name
NM_007611.3 NP_031637.1 caspase-7 precursor

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS01962 CASP7 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS01963 Casp7 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS01964 Casp7 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Casp7 NCBI NCBI:840