2. Gene
  3. Kcna4 - potassium voltage-gated channel, shaker-related subfamily, member 4 Gene

Kcna4 - potassium voltage-gated channel, shaker-related subfamily, member 4 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Kv1.4

Gene ID: 16492 | Gene type: protein coding

About Kcna4

Summary

Predicted to enable delayed rectifier Potassium Channel activity. Predicted to be involved in potassium ion transmembrane transport. Predicted to act upstream of or within regulation of ion transmembrane transport. Located in axon initial segment and membrane. Is expressed in brain; heart; and hindlimb muscle. Orthologous to human KCNA4 (potassium voltage-gated channel subfamily A member 4). [provided by Alliance of Genome Resources, Apr 2022]

Kcna4 Products(1)

mRNA Protein Name
NM_021275.4 NP_067250.2 potassium voltage-gated channel subfamily A member 4
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
12067714 MGI
enables voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential IDA
IDA: Inferred from direct assay
22615428 MGI
enables voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential IMP
IMP: Inferred from mutant phenotype
22615428 MGI
enables voltage-gated potassium channel activity IDA
IDA: Inferred from direct assay
27582084 MGI
Cellular Component GO Annotation Evidence Reference Source
is active in axon initial segment IDA
IDA: Inferred from direct assay
18509034 MGI
located in membrane IDA
IDA: Inferred from direct assay
18603586 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

potassium voltage-gated channel subfamily A member 4

voltage-gated potassium channel subunit Kv1.4

Kcna4 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
Kcna4 Q61423 Dlg4 Mus musculus Q62108
Y2H Array
12067714
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07100 KCNA4 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Kcna4 NCBI NCBI:3739