Slc2a3 - solute carrier family 2 (facilitated glucose transporter), member 3 Gene

Mus musculus

Also known as Glut3; Glut-3

Gene ID: 20527 | Gene type: protein coding

About Slc2a3

Chromosome 6: 122,704,768-122,778,599 reverse strand.GRCm39:CM000999.3

This gene has 8 transcripts (splice variants), 254 orthologues, 11 paralogues and is associated with 9 phenotypes. Biased expression in testis adult (RPKM 213.3), placenta adult (RPKM 31.) and 5 other tissues.

Summary

Enables D-glucose transmembrane transporter activity and dehydroascorbic acid transmembrane transporter activity. Involved in dehydroascorbic acid transport and glucose transmembrane transport. Located in acrosomal membrane and plasma membrane. Is expressed in several structures, including alimentary system; branchial arch; central nervous system; early conceptus; and reproductive system. Orthologous to several human genes including SLC2A3 (solute carrier family 2 member 3). [provided by Alliance of Genome Resources, Apr 2022]

Slc2a3 Products(8)

mRNA	Protein	Name
NM_001410375.1	NP_001397304.1	solute carrier family 2, facilitated glucose transporter member 3 isoform a
NM_001410377.1	NP_001397306.1	solute carrier family 2, facilitated glucose transporter member 3 isoform a
NM_011401.5	NP_035531.3	solute carrier family 2, facilitated glucose transporter member 3 isoform b
NM_001410376.1	NP_001397305.1	solute carrier family 2, facilitated glucose transporter member 3 isoform a
NM_001410372.1	NP_001397301.1	solute carrier family 2, facilitated glucose transporter member 3 isoform d
NM_001410374.1	NP_001397303.1	solute carrier family 2, facilitated glucose transporter member 3 isoform d
NM_001410378.1	NP_001397307.1	solute carrier family 2, facilitated glucose transporter member 3 isoform a
NM_001410371.1	NP_001397300.1	solute carrier family 2, facilitated glucose transporter member 3 isoform c

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables D-glucose transmembrane transporter activity	IDA IDA: Inferred from direct assay	18668520	MGI
enables dehydroascorbic acid transmembrane transporter activity	IDA IDA: Inferred from direct assay	18668520	MGI
enables protein binding	IPI IPI: Inferred from physical interaction	35810171	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in D-glucose transmembrane transport	IDA IDA: Inferred from direct assay	18668520	MGI
acts upstream of or within D-glucose transmembrane transport	IMP IMP: Inferred from mutant phenotype	17213475	MGI
involved in dehydroascorbic acid transport	IDA IDA: Inferred from direct assay	18668520	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in acrosomal membrane	IDA IDA: Inferred from direct assay	19144954	MGI
located in cytoplasm	IDA IDA: Inferred from direct assay	18668520	MGI
located in plasma membrane	IDA IDA: Inferred from direct assay	18668520	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Slc2a3 Protein Structure

MFS_GLUT_Class1

0
100
200
300
400
493 a.a.

Protein Preferred Names

Protein Names

solute carrier family 2, facilitated glucose transporter member 3

glucose transporter type 3, brain

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13167	SLC2A3 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS13168	Slc2a3 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS13169	SLC2A3 Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Slc2a3	NCBI	NCBI:6515

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