2. Gene
  3. IL20 - interleukin 20 Gene

IL20 - interleukin 20 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as IL-20; IL10D; ZCYTO10

Gene ID: 50604 | Gene type: protein coding

About IL20

Cytogenetic location: 1q32.1 Genomic coordinates (GRCh38): 1:206,863,565-206,869,223 (from NCBI)

This gene has 3 transcripts (splice variants), 166 orthologues and 4 paralogues. Low expression observed in reference dataset.

Summary

The protein encoded by this gene is a cytokine structurally related to interleukin 10 (IL10). This cytokine has been shown to transduce its signal through signal transducer and activator of transcription 3 (STAT3) in keratinocytes. A specific receptor for this cytokine is found to be expressed in skin and upregulated dramatically in psoriatic skin, suggesting a role for this protein in epidermal function and psoriasis. [provided by RefSeq, Jul 2008]

IL20 Products(4)

mRNA Protein Name
NM_001385165.1 NP_001372094.1 interleukin-20 isoform 2 precursor
NM_001385166.1 NP_001372095.1 interleukin-20 isoform 1 precursor
NM_001385167.1 NP_001372096.1 interleukin-20 isoform 1 precursor
NM_018724.4 NP_061194.2 interleukin-20 isoform 1 precursor
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
22802649 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

IL20 Protein Structure

IL10

IL10: Interleukin 10 (36 - 173)

  • 0
  • 100
  • 176 a.a.
Protein Preferred Names Protein Names

interleukin-20

cytokine Zcyto10

Recombinant IL20 Proteins

Cat. No. Product Name Accession Purity
HY-P7214 IL-20 Protein, Human Q9NYY1-1 (L25-E176) ≥95%
HY-P700111AF Animal-Free IL-20 Protein, Human (His) Q9NYY1-1 (L25-E176) ≥95%

Related Diseases

Diseases Alias
Psoriasis
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Clinical Phase
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P99198 Fletikumab Inhibitor / Phase 2
Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-106647 Abacavir hydroxyacetate Inhibitor 98.29% Unkown
HY-RS06731 IL20 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS06732 IL20RA Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS06733 IL20RB Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta IL20 VGNC VGNC:99980
Felis catus IL20 VGNC VGNC:107883
Rattus norvegicus IL20 RGD RGD:1583578
Canis familiaris IL20 VGNC VGNC:41964
Bos taurus IL20 VGNC VGNC:30138
Mus musculus IL20 MGD MGI:1890473
Others IL20 NCBI