Gepirone-d₈

Cat. No.: HY-122422S Purity: ≥98.0%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Gepirone-d₈ is deuterium labeled Gepirone.

For research use only. We do not sell to patients.

Gepirone-d<sub>8</sub> Chemical Structure

Gepirone-d₈ Chemical Structure

CAS No. : 2749331-28-8

Size	Price	Stock	Quantity
1 mg	USD 710	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 1750	In-stock	Estimated Time of Arrival: December 31
10 mg		Get quote
50 mg		Get quote

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Other Forms of Gepirone-d₈:

Gepirone Get quote

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Biological Activity
Purity & Documentation
References
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Description

Gepirone-d₈ is deuterium labeled Gepirone.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

367.52

Formula

C₁₉H₂₁D₈N₅O₂

CAS No.

2749331-28-8

Unlabeled CAS

83928-76-1

Appearance

Solid

Color

White to off-white

SMILES

O=C(CC(C)(C)C1)N(CCCCN2C([2H])([2H])C([2H])([2H])N(C3=NC=CC=N3)C([2H])([2H])C2([2H])[2H])C1=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility

In Vitro:

DMSO : 33.33 mg/mL (90.69 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.7209 mL	13.6047 mL	27.2094 mL
5 mM	0.5442 mL	2.7209 mL	5.4419 mL
10 mM	0.2721 mL	1.3605 mL	2.7209 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: ≥98.0%

Select Batch:

Data Sheet (271 KB) SDS (251 KB)

COA (250 KB) HNMR (1916 KB) RP-HPLC (2877 KB) MS (1699 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO / DMSO	1 mM	2.7209 mL	13.6047 mL	27.2094 mL	68.0235 mL
	5 mM	0.5442 mL	2.7209 mL	5.4419 mL	13.6047 mL
	10 mM	0.2721 mL	1.3605 mL	2.7209 mL	6.8024 mL
	15 mM	0.1814 mL	0.9070 mL	1.8140 mL	4.5349 mL
	20 mM	0.1360 mL	0.6802 mL	1.3605 mL	3.4012 mL
	25 mM	0.1088 mL	0.5442 mL	1.0884 mL	2.7209 mL
	30 mM	0.0907 mL	0.4535 mL	0.9070 mL	2.2675 mL
	40 mM	0.0680 mL	0.3401 mL	0.6802 mL	1.7006 mL
	50 mM	0.0544 mL	0.2721 mL	0.5442 mL	1.3605 mL
	60 mM	0.0453 mL	0.2267 mL	0.4535 mL	1.1337 mL
	80 mM	0.0340 mL	0.1701 mL	0.3401 mL	0.8503 mL

Gepirone-d₈ Related Classifications

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Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Gepirone-d₈2749331-28-8Isotope-Labeled Compounds5-HT ReceptorSerotonin Receptor5-hydroxytryptamine ReceptorInhibitorinhibitorinhibit

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Gepirone-d8

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