GLP-1 receptor agonist 10

Cat. No.: HY-153798 Purity: 99.51%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

GLP-1 receptor agonist 10 (compound 42) is an agonist of GLP Receptor. GLP-1 receptor agonist 10 inhibits food intake and reduces glucose excursion in mice. GLP-1 receptor agonist 10 can be used in the study of type 2 diabetes (T2DM) and obesity.

For research use only. We do not sell to patients.

GLP-1 receptor agonist 10 Chemical Structure

CAS No. : 3015555-46-8

Size	Price	Stock	Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	USD 608	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	USD 608	In-stock	Estimated Time of Arrival: December 31
Solid
5 mg	USD 440	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 700	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 1450	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 2350	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 3750	In-stock	Estimated Time of Arrival: December 31
200 mg		Get quote
500 mg		Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Molecular Weight

628.57

Formula

C₃₀H₂₈F₄N₆O₅

CAS No.

3015555-46-8

Appearance

Solid

Color

Off-white to yellow

SMILES

FC(F)(F)C1=CC=C(COC2=CC=CC(N3C=NN(CC4=NC(C(F)=CC(C(O)=O)=C5)=C5N4C[C@@H]6CCO6)CC3)=N2)C(OC)=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 125 mg/mL (198.86 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.5909 mL	7.9546 mL	15.9091 mL
5 mM	0.3182 mL	1.5909 mL	3.1818 mL
10 mM	0.1591 mL	0.7955 mL	1.5909 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.51%

Select Batch:

Data Sheet (269 KB) SDS (251 KB)

COA (247 KB) HNMR (320 KB) LCMS (98 KB)

Handling Instructions (2659 KB)

References

[1]. Chen L, et al. Discovery of Novel 5,6-Dihydro-1,2,4-triazine Derivatives as Efficacious Glucagon-Like Peptide-1 Receptor Agonists. J Med Chem. 2023 Jun 22;66(12):7988-8010. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.5909 mL	7.9546 mL	15.9091 mL	39.7728 mL
	5 mM	0.3182 mL	1.5909 mL	3.1818 mL	7.9546 mL
	10 mM	0.1591 mL	0.7955 mL	1.5909 mL	3.9773 mL
	15 mM	0.1061 mL	0.5303 mL	1.0606 mL	2.6515 mL
	20 mM	0.0795 mL	0.3977 mL	0.7955 mL	1.9886 mL
	25 mM	0.0636 mL	0.3182 mL	0.6364 mL	1.5909 mL
	30 mM	0.0530 mL	0.2652 mL	0.5303 mL	1.3258 mL
	40 mM	0.0398 mL	0.1989 mL	0.3977 mL	0.9943 mL
	50 mM	0.0318 mL	0.1591 mL	0.3182 mL	0.7955 mL
	60 mM	0.0265 mL	0.1326 mL	0.2652 mL	0.6629 mL
	80 mM	0.0199 mL	0.0994 mL	0.1989 mL	0.4972 mL
	100 mM	0.0159 mL	0.0795 mL	0.1591 mL	0.3977 mL