1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. H-Asn(glcnac-beta-D)-OH

H-Asn(glcnac-beta-D)-OH is an endogenous metabolite present in Urine that can be used for the research of NGLY1-CDDG.

For research use only. We do not sell to patients.

H-Asn(glcnac-beta-D)-OH Chemical Structure

H-Asn(glcnac-beta-D)-OH Chemical Structure

CAS No. : 2776-93-4

Size Price Stock Quantity
5 mg USD 110 In-stock
10 mg USD 190 In-stock
25 mg USD 380 In-stock
50 mg   Get quote  
100 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

H-Asn(glcnac-beta-D)-OH is an endogenous metabolite present in Urine that can be used for the research of NGLY1-CDDG[1][2].

IC50 & Target

Human Endogenous Metabolite

 

In Vitro

Endogenous metabolites is defined as those that are annotated by Kyoto Encyclopedia of Genes and Genomes as substrates or products of the ~1900 metabolic enzymes encoded in our genome. It is clear in the body of literature that there are documented toxic properties for many of these metabolites[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

335.31

Formula

C12H21N3O8

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

OC([C@@H](N)CC(N[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)NC(C)=O)=O)=O

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 125 mg/mL (372.79 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9823 mL 14.9116 mL 29.8231 mL
5 mM 0.5965 mL 2.9823 mL 5.9646 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 2.9823 mL 14.9116 mL 29.8231 mL 74.5579 mL
5 mM 0.5965 mL 2.9823 mL 5.9646 mL 14.9116 mL
10 mM 0.2982 mL 1.4912 mL 2.9823 mL 7.4558 mL
15 mM 0.1988 mL 0.9941 mL 1.9882 mL 4.9705 mL
20 mM 0.1491 mL 0.7456 mL 1.4912 mL 3.7279 mL
25 mM 0.1193 mL 0.5965 mL 1.1929 mL 2.9823 mL
30 mM 0.0994 mL 0.4971 mL 0.9941 mL 2.4853 mL
40 mM 0.0746 mL 0.3728 mL 0.7456 mL 1.8639 mL
50 mM 0.0596 mL 0.2982 mL 0.5965 mL 1.4912 mL
60 mM 0.0497 mL 0.2485 mL 0.4971 mL 1.2426 mL
80 mM 0.0373 mL 0.1864 mL 0.3728 mL 0.9320 mL
100 mM 0.0298 mL 0.1491 mL 0.2982 mL 0.7456 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
H-Asn(glcnac-beta-D)-OH
Cat. No.:
HY-N9446
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