2. Immunology/Inflammation NF-κB Metabolic Enzyme/Protease
  3. Reactive Oxygen Species
  4. Lobenzarit disodium

Lobenzarit disodium  (Synonyms: CCA)

Cat. No.: HY-107360 Purity: 99.94%
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Lobenzarit disodium (CCA) is an anti-arthritic and anti-oxidative agent.

For research use only. We do not sell to patients.

Lobenzarit disodium Chemical Structure

Lobenzarit disodium Chemical Structure

CAS No. : 64808-48-6

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5 mg USD 86 In-stock
10 mg USD 137 In-stock
25 mg USD 234 In-stock
50 mg USD 375 In-stock
100 mg USD 600 In-stock
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Based on 1 publication(s) in Google Scholar

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Lobenzarit disodium Related Antibodies

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Description

Lobenzarit disodium (CCA) is an anti-arthritic and anti-oxidative agent[1].

In Vitro

Lobenzarit disodium (CCA) inhibits chemiluminescence induced by activated oxygen with an IC50 of 1.6 μM[1].
Lobenzarit disodium (0.3-300 μM) inhibits the production of lipid peroxide and the IgG alteration induced by UV irradiation[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Lobenzarit disodium Related Antibodies
In Vivo

Lobenzarit disodium (CCA; 10 and 50 mg/kg; i.p.; daily for 7 days) exerts its anti-arthritic effect through the activation of suppressor T lymphocytes[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Sprague-Dawley rats[2]
Dosage: 10 and 50 mg/kg
Administration: IP; daily for 7 days
Result: Showed anti-arthritic effect, but had no therapeutic effect in arthritic rats which were depleted of T lymphocytes.
Clinical Trial
Molecular Weight

335.65

Formula

C14H8ClNNa2O4
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(O[Na])C(C=CC(Cl)=C1)=C1NC2=C(C=CC=C2)C(O[Na])=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 4.85 mg/mL (14.45 mM; ultrasonic and warming and adjust pH to 5 with HCl and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9793 mL 14.8965 mL 29.7929 mL
5 mM 0.5959 mL 2.9793 mL 5.9586 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.9793 mL 14.8965 mL 29.7929 mL 74.4823 mL
5 mM 0.5959 mL 2.9793 mL 5.9586 mL 14.8965 mL
10 mM 0.2979 mL 1.4896 mL 2.9793 mL 7.4482 mL
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Lobenzarit disodium Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Lobenzarit disodium64808-48-6CCAReactive Oxygen SpeciesInhibitorinhibitorinhibit

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