2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. NAD sodium

NAD sodium  (Synonyms: β-DPN sodium; β-NAD sodium; β-Nicotinamide Adenine Dinucleotide sodium)

Cat. No.: HY-B0445A Purity: 99.07%
SDS COA Handling Instructions

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NAD (β-Nicotinamide Adenine Dinucleotide) sodium is an analogue of NAD. NAD sodium can be reduced to β-nicotinamide adenine dinucleotide (NADH) during coupling with reactions which oxidize organic substrates. NAD sodium can be converted to β-nicotinamide adenine dinucleotide (NADH) and passes to the inside of mitochondria that indirectly generates ATP.

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NAD sodium Chemical Structure

NAD sodium Chemical Structure

CAS No. : 20111-18-6

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Based on 27 publication(s) in Google Scholar

Other Forms of NAD sodium:

NAD sodium Related Antibodies

Top Publications Citing Use of Products

    NAD sodium purchased from MedChemExpress. Usage Cited in: Vascul Pharmacol. 2022 Nov 6;147:107126.  [Abstract]

    NAD+ significantly improves the expression of VEGF in the MI mice and DM + MI mice.

    NAD sodium purchased from MedChemExpress. Usage Cited in: Vascul Pharmacol. 2022 Nov 6;147:107126.  [Abstract]

    NAD+ significantly improves the expression of CD31 in the MI mice and DM + MI mice.

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    Description

    NAD (β-Nicotinamide Adenine Dinucleotide) sodium is an analogue of NAD. NAD sodium can be reduced to β-nicotinamide adenine dinucleotide (NADH) during coupling with reactions which oxidize organic substrates. NAD sodium can be converted to β-nicotinamide adenine dinucleotide (NADH) and passes to the inside of mitochondria that indirectly generates ATP[1].

    Molecular Weight

    685.41

    Formula

    C21H26N7NaO14P2
    CAS No.
    Appearance

    Solid

    Color

    White to off-white

    SMILES

    O[C@H]1[C@@H](O)[C@H]([N+]2=CC=CC(C(N)=O)=C2)O[C@@H]1COP([O-])(OP(OC[C@@H]3[C@@H](O)[C@@H](O)[C@H](N4C5=NC=NC(N)=C5N=C4)O3)(O[Na])=O)=O
    Shipping

    Room temperature in continental US; may vary elsewhere.
    Storage

    -20°C, sealed storage, away from moisture

    *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

    Solvent & Solubility
    In Vitro: 

    H2O : 125 mg/mL (182.37 mM; Need ultrasonic)

    DMSO : 25 mg/mL (36.47 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

    Preparing
    Stock Solutions
    Concentration Solvent Mass 1 mg 5 mg 10 mg
    1 mM 1.4590 mL 7.2949 mL 14.5898 mL
    5 mM 0.2918 mL 1.4590 mL 2.9180 mL
    View the Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
    Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

    * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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    • Dilution Calculator

    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

    This equation is commonly abbreviated as: C1V1 = C2V2

    Concentration (start)

    C1

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    In Vivo Dissolution Calculator
    Please enter the basic information of animal experiments:

    Dosage

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    Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
    Calculation results:
    Working solution concentration: mg/mL
    This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
    The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
    Purity & Documentation

    Purity: 99.07%

    SDS (557 KB)

    COA (261 KB) HNMR (301 KB) CNMR (354 KB) RP-HPLC (195 KB) MS (68 KB)

    Handling Instructions (2659 KB)
    References

    Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
    Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

    Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
    DMSO / H2O 1 mM 1.4590 mL 7.2949 mL 14.5898 mL 36.4745 mL
    5 mM 0.2918 mL 1.4590 mL 2.9180 mL 7.2949 mL
    10 mM 0.1459 mL 0.7295 mL 1.4590 mL 3.6475 mL
    15 mM 0.0973 mL 0.4863 mL 0.9727 mL 2.4316 mL
    20 mM 0.0729 mL 0.3647 mL 0.7295 mL 1.8237 mL
    25 mM 0.0584 mL 0.2918 mL 0.5836 mL 1.4590 mL
    30 mM 0.0486 mL 0.2432 mL 0.4863 mL 1.2158 mL
    H2O 40 mM 0.0365 mL 0.1824 mL 0.3647 mL 0.9119 mL
    50 mM 0.0292 mL 0.1459 mL 0.2918 mL 0.7295 mL
    60 mM 0.0243 mL 0.1216 mL 0.2432 mL 0.6079 mL
    80 mM 0.0182 mL 0.0912 mL 0.1824 mL 0.4559 mL
    100 mM 0.0146 mL 0.0729 mL 0.1459 mL 0.3647 mL

    * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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    NAD sodium Related Classifications

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    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    NAD20111-18-6β-DPNβ-NADβ-Nicotinamide Adenine DinucleotideEndogenous Metaboliteβ-nicotinamide adenine dinucleotideATPmitochondriaInhibitorinhibitorinhibit

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