2. GPCR/G Protein
  3. Neuropeptide FF Receptor
  4. palm-PrRP31

palm-PrRP31 is a potent dual receptor agonist for both GPR10 (EC50=72 pM) and NPFF-R2. palm-PrRP31 activates downstream signaling pathways through binding to its receptors, GPR10 and NPFF-R2, which results in reduced appetite and increased energy expenditure. Utilizing palm-PrRP31 facilitates the study of the mechanism of action in the nervous system, thereby elucidating the complex biological processes that regulate appetite and energy expenditure.

For research use only. We do not sell to patients.

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palm-PrRP31 Chemical Structure

palm-PrRP31 Chemical Structure

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palm-PrRP31 Related Antibodies

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NPFFR1 NPFFR2

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Description

palm-PrRP31 is a potent dual receptor agonist for both GPR10 (EC50=72 pM) and NPFF-R2. palm-PrRP31 activates downstream signaling pathways through binding to its receptors, GPR10 and NPFF-R2, which results in reduced appetite and increased energy expenditure. Utilizing palm-PrRP31 facilitates the study of the mechanism of action in the nervous system, thereby elucidating the complex biological processes that regulate appetite and energy expenditure[1].

Molecular Weight

3902.54

Formula

C176H282N56O43S
Sequence

{N-palm-Ser}-Arg-Thr-His-Arg-His-Ser-Met-Glu-Ile-Arg-Thr-Pro-Asp-Ile-Asn-Pro-Ala-Trp-Tyr-Ala-Ser-Arg-Gly-Ile-Arg-Pro-Val-Gly-Arg-Phe-NH2 (palm=palmitoyl (C16))
Sequence Shortening

{N-palm-Ser}-RTHRHSMEIRTPDINPAWYASRGIRPVGRF-NH2 (palm=palmitoyl (C16))
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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palm-PrRP31 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

palm-PrRP31Neuropeptide FF ReceptorDouble receptor agonistAppetite RegulationNervous systemGPR10NPFF-R2Inhibitorinhibitorinhibit

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