2. Epigenetics Cell Cycle/DNA Damage TGF-beta/Smad
  3. CDK PKC
  4. PKCζ-IN-1

PKCζ-IN-1 is a compound that inhibits PKCζ and CDK2, showing an IC50 value of 5.18 nM for PKCζ and 1.04 μM for CDK2, with significant selectivity of 200-fold. PKCζ-IN-1 can reduce the activity of CDK2 while inhibiting PKCζ.

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PKCζ-IN-1 Chemical Structure

PKCζ-IN-1 Chemical Structure

CAS No. : 1132609-87-0

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Based on 1 publication(s) in Google Scholar

PKCζ-IN-1 Related Antibodies

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Description

PKCζ-IN-1 is a compound that inhibits PKCζ and CDK2, showing an IC50 value of 5.18 nM for PKCζ and 1.04 μM for CDK2, with significant selectivity of 200-fold. PKCζ-IN-1 can reduce the activity of CDK2 while inhibiting PKCζ.

Molecular Weight

423.51

Formula

C25H25N7
CAS No.
Appearance

Solid

Color

White to light yellow

SMILES

CN(CC1)CCN1C2=CC=CC3=C2NC(C4=NNC5=C4C=CC(C6=CC=C(N)C=C6)=C5)=N3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation

Purity: 99.1%

SDS (393 KB)

COA (257 KB)

Handling Instructions (2659 KB)
References
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PKCζ-IN-1 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PKCζ-IN-11132609-87-0CDKPKCCyclin dependent kinaseProtein kinase CInhibitorinhibitorinhibit

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