2. Antibody-drug Conjugate/ADC Related
  3. ADC Linker
  4. PTAD-PEG8-azide

PTAD-PEG8-azide is a cleavable ADC linker containing an azide group. PTAD-PEG8-azide can be used in the synthesis of antibody-drug conjugates (ADCs).

For research use only. We do not sell to patients.

PTAD-PEG8-azide Chemical Structure

PTAD-PEG8-azide Chemical Structure

Size Stock
50 mg   Get quote  
100 mg   Get quote  
250 mg   Get quote  
Synthetic products have potential research and development risk.

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

PTAD-PEG8-azide Related Antibodies

Top Publications Citing Use of Products

View All ADC Linker Isoform Specific Products:

View All Isoforms
Cleavable Linker Non-cleavable Linker Acid Cleavable Linker Disulfide Cleavable Linker Protease Cleavable Linker Glycosidase Cleavable Linker Phosphatase Cleavable Linker

  • Biological Activity

  • Purity & Documentation

  • Customer Review

Description

PTAD-PEG8-azide is a cleavable ADC linker containing an azide group. PTAD-PEG8-azide can be used in the synthesis of antibody-drug conjugates (ADCs).

IC50 & Target

Cleavable Linker

 

Molecular Weight

715.75

Formula

C30H49N7O13
SMILES

COC1=C(OCCNC(CCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-])=O)C=CC(N2C(NNC2=O)=O)=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (174.64 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.3971 mL 6.9857 mL 13.9714 mL
5 mM 0.2794 mL 1.3971 mL 2.7943 mL
View the Complete Stock Solution Preparation Table

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Complete Stock Solution Preparation Table

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.3971 mL 6.9857 mL 13.9714 mL 34.9284 mL
5 mM 0.2794 mL 1.3971 mL 2.7943 mL 6.9857 mL
10 mM 0.1397 mL 0.6986 mL 1.3971 mL 3.4928 mL
15 mM 0.0931 mL 0.4657 mL 0.9314 mL 2.3286 mL
20 mM 0.0699 mL 0.3493 mL 0.6986 mL 1.7464 mL
25 mM 0.0559 mL 0.2794 mL 0.5589 mL 1.3971 mL
30 mM 0.0466 mL 0.2329 mL 0.4657 mL 1.1643 mL
40 mM 0.0349 mL 0.1746 mL 0.3493 mL 0.8732 mL
50 mM 0.0279 mL 0.1397 mL 0.2794 mL 0.6986 mL
60 mM 0.0233 mL 0.1164 mL 0.2329 mL 0.5821 mL
80 mM 0.0175 mL 0.0873 mL 0.1746 mL 0.4366 mL
100 mM 0.0140 mL 0.0699 mL 0.1397 mL 0.3493 mL
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

PTAD-PEG8-azide Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PTAD-PEG8-azideADC LinkerAntibody-drug conjugates linkerADC likercleavableInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
PTAD-PEG8-azide
Cat. No.:
HY-164929
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

SAFETY DATA SHEET (SDS)

English - EN (0 KB) Français - FR (0 KB) Deutsch - DE (0 KB) Norwegian - NO (0 KB) Español - ES (0 KB) Swedish - SV (0 KB)

Request for HNMR Report

We have received your request and will respond to you as soon as possible.