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OSI-7904

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-10823
    OSI-7904L

    GW1843; 1843U89; OSI-7904

    		 Antifolate Thymidylate Synthase Cancer
    OSI-7904L (GW1843) is a noncompetitive inhibitor of thymidylate synthase (TS). OSI-7904L is an antifolate compound and a substrate for folylpolyglutamate synthetase. OSI-7904L has cytotoxicity against solid tumor lines, and the toxicity can be selectively blocked by folic acid .
    OSI-7904L

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