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Results for "

30A5

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Biochemical Assay Reagents (2) Calcium Channel (1) Drug Intermediate (1) Isotope-Labeled Compounds (1) MicroRNA (20) Potassium Channel (1) Small Interfering RNA (siRNA) (1) VEGFR (4)
By Research Areas:	Cancer (24) Cardiovascular Disease (1) Inflammation/Immunology (1) Metabolic Disease (1) Neurological Disease (1)
Oligonucleotides:	miRNA mimics (5) miRNA agomirs (5) miRNA antagomirs (5) MicroRNAs (20) Pre-designed siRNA Sets (1) miRNA inhibitors (5) siRNAs (1)

Inhibitors & Agonists

Biochemical Assay Reagents

Natural
Products

Isotope-Labeled Compounds

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N9960

α-Isopropylmalate α-IPM	Drug Intermediate	Others
α-Isopropylmalate (α-IPM) is the leucine biosynthetic precursor in Yeast .

HY-R00535

*hsa-miR-30a-5p mimic*	MicroRNA	Cancer
hsa-miR-30a-5p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

hsa-miR-30a-5p mimic hsa-miR-30a-5p mimic

HY-RI00535

*hsa-miR-30a-5p inhibitor*	MicroRNA	Cancer
hsa-miR-30a-5p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

hsa-miR-30a-5p inhibitor hsa-miR-30a-5p inhibitor

HY-RS13183

SLC30A5 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SLC30A5 Human Pre-designed siRNA Set A contains three designed siRNAs for SLC30A5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SLC30A5 Human Pre-designed siRNA Set A SLC30A5 Human Pre-designed siRNA Set A

HY-R00535A

*hsa-miR-30a-5p agomir*	MicroRNA	Cancer
hsa-miR-30a-5p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-30a-5p agomir hsa-miR-30a-5p agomir

HY-RI00535A

*hsa-miR-30a-5p antagomir*	MicroRNA	Cancer
hsa-miR-30a-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-30a-5p antagomir hsa-miR-30a-5p antagomir

HY-N9960R

α-Isopropylmalate (Standard) α-IPM (Standard)	Others	Others
α-Isopropylmalate (Standard) is the analytical standard of α-Isopropylmalate. This product is intended for research and analytical applications. α-Isopropylmalate (α-IPM) is the leucine biosynthetic precursor in Yeast .

HY-R00537

*hsa-miR-30b-5p mimic*	MicroRNA	Cancer
hsa-miR-30b-5p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

hsa-miR-30b-5p mimic hsa-miR-30b-5p mimic

HY-R00540

*hsa-miR-30c-5p mimic*	MicroRNA	Cancer
hsa-miR-30c-5p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

hsa-miR-30c-5p mimic hsa-miR-30c-5p mimic

HY-R00542

*hsa-miR-30d-5p mimic*	MicroRNA	Cancer
hsa-miR-30d-5p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

hsa-miR-30d-5p mimic hsa-miR-30d-5p mimic

HY-R00544

*hsa-miR-30e-5p mimic*	MicroRNA	Cancer
hsa-miR-30e-5p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

hsa-miR-30e-5p mimic hsa-miR-30e-5p mimic

HY-N10436

Anti-inflammatory agent 30	Others	Metabolic Disease Inflammation/Immunology
Anti-inflammatory agent 30 (Compound 5) is an anti-inflammatory agent with hepatoprotective activity .

HY-RI00537

*hsa-miR-30b-5p inhibitor*	MicroRNA	Cancer
hsa-miR-30b-5p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

hsa-miR-30b-5p inhibitor hsa-miR-30b-5p inhibitor

HY-RI00540

*hsa-miR-30c-5p inhibitor*	MicroRNA	Cancer
hsa-miR-30c-5p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

hsa-miR-30c-5p inhibitor hsa-miR-30c-5p inhibitor

HY-RI00542

*hsa-miR-30d-5p inhibitor*	MicroRNA	Cancer
hsa-miR-30d-5p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

hsa-miR-30d-5p inhibitor hsa-miR-30d-5p inhibitor

HY-RI00544

*hsa-miR-30e-5p inhibitor*	MicroRNA	Cancer
hsa-miR-30e-5p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

hsa-miR-30e-5p inhibitor hsa-miR-30e-5p inhibitor

HY-R00537A

*hsa-miR-30b-5p agomir*	MicroRNA	Cancer
hsa-miR-30b-5p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-30b-5p agomir hsa-miR-30b-5p agomir

HY-R00540A

*hsa-miR-30c-5p agomir*	MicroRNA	Cancer
hsa-miR-30c-5p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-30c-5p agomir hsa-miR-30c-5p agomir

HY-R00542A

*hsa-miR-30d-5p agomir*	MicroRNA	Cancer
hsa-miR-30d-5p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-30d-5p agomir hsa-miR-30d-5p agomir

HY-R00544A

*hsa-miR-30e-5p agomir*	MicroRNA	Cancer
hsa-miR-30e-5p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-30e-5p agomir hsa-miR-30e-5p agomir

HY-W008240

2′,3′-Isopropylideneguanosine	Biochemical Assay Reagents	Others
2', 3'-Isopropylideneguanosine (Compound 2) is the precursor of m ^{7,20,30-isopropylideneG}[5']ppp[5']G .

HY-136615

5-Hydroxydecanoate sodium	Potassium Channel	Neurological Disease
5-Hydroxydecanoate sodium is a selective ATP-sensitive K ⁺ (K_ATP) channel blocker (IC₅₀ of ~30 μM). 5-Hydroxydecanoate sodium is a substrate for mitochondrial outer membrane acyl-CoA synthetase and has antioxidant activity .

HY-RI00537A

*hsa-miR-30b-5p antagomir*	MicroRNA	Cancer
hsa-miR-30b-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-30b-5p antagomir hsa-miR-30b-5p antagomir

HY-RI00540A

*hsa-miR-30c-5p antagomir*	MicroRNA	Cancer
hsa-miR-30c-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-30c-5p antagomir hsa-miR-30c-5p antagomir

HY-RI00542A

*hsa-miR-30d-5p antagomir*	MicroRNA	Cancer
hsa-miR-30d-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-30d-5p antagomir hsa-miR-30d-5p antagomir

HY-RI00544A

*hsa-miR-30e-5p antagomir*	MicroRNA	Cancer
hsa-miR-30e-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-30e-5p antagomir hsa-miR-30e-5p antagomir

HY-10977

Tivozanib Maximum Cited Publications 8 Publications Verification AV-951; KRN951	VEGFR	Cancer
Tivozanib (AV-951; KRN951) is a selective, orally active inhibitor for vascular endothelial growth factor receptor (VEGFR)-1, 2 3, with IC₅₀s of 30, 6.5 and 15 nM, respectively. Tivozanib exhibits antitumor efficacy .

HY-10977A

Tivozanib hydrochloride hydrate Maximum Cited Publications 8 Publications Verification AV-951 hydrochloride hydrate; KRN951 hydrochloride hydrate	VEGFR	Cancer
Tivozanib hydrochloride hydrate is the hydrate hydrochloride form of Tivozanib (HY-10977). Tivozanib hydrochloride hydrate is a selective, orally active inhibitor for vascular endothelial growth factor receptor (VEGFR)-1, 2 3, with IC₅₀s of 30, 6.5 and 15 nM, respectively. Tivozanib hydrochloride hydrate exhibits antitumor efficacy .

HY-112467

Tivozanib hydrate Maximum Cited Publications 8 Publications Verification AV-951 hydrate; KRN951 hydrate	VEGFR	Cancer
Tivozanib hydrate (AV-951 hydrate; KRN951 hydrate) is the hydrate form of Tivozanib (HY-10977). Tivozanib hydrate is a selective, orally active inhibitor for vascular endothelial growth factor receptor (VEGFR)-1, 2 3, with IC₅₀s of 30, 6.5 and 15 nM, respectively. Tivozanib hydrate exhibits antitumor efficacy .

HY-138560

Cross-linked dextran G 50 1 Publications Verification	Biochemical Assay Reagents	Others
Cross-linked dextran G 50 is a gel filtration medium. Cross-linked dextran G 50 can be used in gel permeation chromatography for fractionation of the glycopeptide mixture (Sphere protein separation range: 1.5K-30K Da; Polysaccharide separation range: 500-10K Da) .

HY-10977S

Tivozanib-d6 AV-951-d₆; KRN951-d₆	Isotope-Labeled Compounds VEGFR	Cancer
Tivozanib-d₆ (AV-951-d₆) is deuterium labeled Tivozanib. Tivozanib (AV-951; KRN951) is a selective, orally active inhibitor for vascular endothelial growth factor receptor (VEGFR)-1, 2 3, with IC₅₀s of 30, 6.5 and 15 nM, respectively. Tivozanib exhibits antitumor efficacy .

HY-101390A

(-)-Niguldipine hydrochloride (R)-Niguldipine hydrochloride	Calcium Channel	Cardiovascular Disease
(-)-Niguldipine ((R)-Niguldipine) hydrochloride is a calcium channel antagonist. (-)-Niguldipine hydrochloride exerts a vasodilatory effect by blocking calcium channels and reducing the transmembrane influx of calcium ions. (-)-Niguldipine can inhibit U-46619 (HY-108566)-induced coronary artery contraction in guinea pig Langendorff hearts (pID₅₀ of 9.93), has high affinity for calcium channel binding sites on guinea pig skeletal muscle membranes (K_i of 8.10), and lowers blood pressure in spontaneously hypertensive rats (pED₃₀* of 5*.55). (-)-Niguldipine hydrochloride can improve cardiovascular diseases such as hypertension, angina pectoris, and arrhythmias .

Cat. No.	Product Name	Type