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ALK/EGFR-IN-1-d5

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Anaplastic lymphoma kinase (ALK) (1) EGFR (1) Apoptosis (1) BRK (1) Isotope-Labeled Compounds (1) Mitochondrial Metabolism (1)
By Research Areas:	Cancer (1)

Targets Recommended: EGFR Anaplastic lymphoma kinase (ALK) Dan family AIM2 NEKs

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-155227S

*ALK/EGFR-IN-1-d5*	Isotope-Labeled Compounds EGFR Anaplastic lymphoma kinase (ALK) BRK Apoptosis Mitochondrial Metabolism	Cancer
ALK/EGFR-IN-1-d5 (Compound (-)-9a) is a deuterated dual-target inhibitor of *EGFR* and *ALK, with an IC₅₀* of 1.08 nM for *EGFR* and an IC₅₀ of 2.395 nM for *ALK. ALK/EGFR-IN-1-d5* inhibits the phosphorylated proteins in the *EGFR, ALK, and BRK* signaling pathways, blocking the cell cycle, leading to a reduction in mitochondrial membrane potential and cell apoptosis (Apoptosis). ALK/EGFR-IN-1-d5 also significantly inhibits tumor growth in animal models and demonstrates good safety. ALK/EGFR-IN-1-d5 holds promise for research in the field of cancer treatment

Cat. No.	Product Name	Chemical Structure

HY-155227S

*ALK/EGFR-IN-1-d5*
ALK/EGFR-IN-1-d5 (Compound (-)-9a) is a deuterated dual-target inhibitor of *EGFR* and *ALK, with an IC₅₀* of 1.08 nM for *EGFR* and an IC₅₀ of 2.395 nM for *ALK. ALK/EGFR-IN-1-d5* inhibits the phosphorylated proteins in the *EGFR, ALK, and BRK* signaling pathways, blocking the cell cycle, leading to a reduction in mitochondrial membrane potential and cell apoptosis (Apoptosis). ALK/EGFR-IN-1-d5 also significantly inhibits tumor growth in animal models and demonstrates good safety. ALK/EGFR-IN-1-d5 holds promise for research in the field of cancer treatment

ALK/EGFR-IN-1-d5

ALK/EGFR-IN-1-d5 (Compound (-)-9a) is a deuterated dual-target inhibitor of EGFR and ALK, with an IC₅₀ of 1.08 nM for EGFR and an IC₅₀ of 2.395 nM for ALK. ALK/EGFR-IN-1-d5 inhibits the phosphorylated proteins in the EGFR, ALK, and BRK signaling pathways, blocking the cell cycle, leading to a reduction in mitochondrial membrane potential and cell apoptosis (Apoptosis). ALK/EGFR-IN-1-d5 also significantly inhibits tumor growth in animal models and demonstrates good safety. ALK/EGFR-IN-1-d5 holds promise for research in the field of cancer treatment

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ALK/EGFR-IN-1-d5

Inhibitors & Agonists

Isotope-Labeled Compounds