Search Result
Results for "
Anthelmintic
" in MedChemExpress (MCE) Product Catalog:
12
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
-
- HY-123305
-
|
Parasite
|
Others
|
5-Hydroxymebendazole is the one metabolite of Benzimidazoles. Benzimidazoles are safe, broad-spectrum anthelmintic agents and are widely used for prevention and treatment of parasitic infections in food-producing animals .
|
-
-
- HY-112542
-
CL-287088; LL-F28249 α
|
Parasite
Antibiotic
|
Infection
|
Nemadectin (CL-287088), an orally active broad-spectrum endectocide, is highly efficacious against natural infections of all the major canine gastrointestinal helminthes. Anthelmintic activity .
|
-
-
- HY-Y0055
-
-
-
- HY-123192
-
Sansalid
|
Parasite
|
Infection
|
Uredofos is a broad-spectrum anthelmintic. Uredofos has anticestodal activity .
|
-
-
- HY-137141
-
SB202327
|
Parasite
|
Infection
|
16-Keto Aspergillimide (SB202327) is an anthelmintic agent isolated from Aspergillus strain IMI 337664 .
|
-
-
- HY-138194
-
A-16316-C
|
Antibiotic
Fungal
|
Infection
|
Destomycin B (A-16316-C) is an antibiotic, and is active against fungi. Destomycin B also has anthelmintic activity .
|
-
-
- HY-120479
-
|
Cholinesterase (ChE)
|
Neurological Disease
|
Cythioate is an organophosphorous insecticide and anthelmintic. Cythioate is an acetylcholinesterase inhibitor which interferes with neuromuscular transmission in ectoparastites .
|
-
-
- HY-122765
-
HOE 216V
|
Parasite
|
Infection
|
Luxabendazole (HOE 216V) is an effective anthelmintic against trematodes, cestodes and nematodes .
|
-
-
- HY-N15029
-
|
Antibiotic
Bacterial
Fungal
Parasite
Adenylate Cyclase
|
Infection
|
Destomycin A is an aminoglycoside antibiotic with antibacterial (Gram-positive bacteria, Gram-negative bacteria), antifungal and anthelmintic activities. Destomycin A inhibits the polypeptide synthesis in cells of Escherichia coli and stimulation of adenylate cyclase in animal tissues .
|
-
-
- HY-124498
-
CP-14445
|
nAChR
Parasite
|
Infection
|
Oxantel (CP-14445), a m-oxyphenol derivative of Pyrantel (HY-12641), is a N-subtype AChR agonist. Oxantel is an anthelmintic, with excellent trichuricidal properties .
|
-
-
- HY-N8378
-
|
Others
|
Infection
|
Clonostachydiol is an anthelmintic macrodiolide from the fungus Clonostachys cylindrospora (strain FH-A 6607) .
|
-
-
- HY-12361
-
|
Parasite
|
Infection
|
PF 1022A is a cyclooctadepsipeptide with broadspectrum anthelmintic properties produced by fermentation of the fungus Mycelia sterilia. PF 1022A is a channel-forming ionophore. PF 1022A showes strong anthelmintic activities against Ascaridia galli in chickens. PF 1022A also can be used for angiostrongyliasis research .
|
-
-
- HY-W049875
-
|
Parasite
|
Infection
|
Nitroxynil, anthelmintic agent, is active against parasites in both adult and immature stages. Nitroxynil is widely used for the research of infection of Fasciola hepatica .
|
-
-
- HY-113715
-
BAY 9015; Menichlopholan; Menichlofolan; Bilevon
|
Parasite
|
Infection
|
Niclofolan (BAY 9015) is an orally active anthelmintic agent. Niclofolan can be used in the research of parasite infection .
|
-
-
- HY-W011239
-
Oxfendazole sulfone; FBZ-SO2
|
Parasite
|
Infection
|
Fenbendazole sulfone (Oxfendazole sulfone;FBZ-SO2) is a minor metabolite of Fenbendazole in plasma and is a benzimidazole anthelmintic agent .
|
-
-
- HY-112542R
-
|
Parasite
Antibiotic
|
Infection
|
Nemadectin (Standard) is the analytical standard of Nemadectin. This product is intended for research and analytical applications. Nemadectin (CL-287088), an orally active broad-spectrum endectocide, is highly efficacious against natural infections of all the major canine gastrointestinal helminthes. Anthelmintic activity .
|
-
-
- HY-19054
-
|
Parasite
|
Infection
|
CGP-20376, a 5-methoxyl-6-dithiocarbamic-S- (2-carboxy-ethyl) ester derivative of Benzothiazole (HY-W012634), is an orally active and potent antifilarial drug. CGP-20376 has anthelmintic activity .
|
-
-
- HY-Y0055R
-
|
Antibiotic
Fungal
Bacterial
Parasite
|
Infection
Neurological Disease
|
Phenothiazine (Standard) is the analytical standard of Phenothiazine. This product is intended for research and analytical applications. Phenothiazine is an antibiotic which has insecticidal, fungicidal, antibacterial and anthelmintic activities. Phenothiazine also can be used for the research of neurological diseases .
|
-
-
- HY-123305R
-
|
Parasite
|
Others
|
5-Hydroxymebendazole (Standard) is the analytical standard of 5-Hydroxymebendazole. This product is intended for research and analytical applications. 5-Hydroxymebendazole is the one metabolite of Benzimidazoles. Benzimidazoles are safe, broad-spectrum anthelmintic agents and are widely used for prevention and treatment of parasitic infections in food-producing animals .
|
-
-
- HY-B1636
-
|
Parasite
|
Infection
|
Dithiazanine iodide is an effective broad-spectrum anthelmintic. Dithiazanine iodide can be used for the research of trichuriasis, strongyloidiasis, enterobiasis, ascariasis, and hookworm infection. Dithiazanine iodide is also a cyanine dye .
|
-
-
- HY-W049875R
-
|
Parasite
|
Infection
|
Nitroxynil (Standard) is the analytical standard of Nitroxynil. This product is intended for research and analytical applications. Nitroxynil, anthelmintic agent, is active against parasites in both adult and immature stages. Nitroxynil is widely used for the research of infection of Fasciola hepatica .
|
-
-
- HY-W011239R
-
|
Parasite
|
Infection
|
Fenbendazole sulfone (Standard) is the analytical standard of Fenbendazole sulfone. This product is intended for research and analytical applications. Fenbendazole sulfone (Oxfendazole sulfone;FBZ-SO2) is a minor metabolite of Fenbendazole in plasma and is a benzimidazole anthelmintic agent .
|
-
-
- HY-124874
-
(rel)-Aspergillimide; (rel)-VM55598
|
nAChR
|
Neurological Disease
|
(rel)-Asperparaline A ((rel)-Aspergillimide), an anthelmintic metabolite, is isolated from okara that has been fermented with Aspergillus japonicas JV-23. (rel)-Asperparaline A is also a potent and selective antagonist of nAChR. (rel)-Asperparaline A exhibits paralytic activity in silk worms .
|
-
-
- HY-W158234
-
|
Parasite
|
Infection
|
N-Methylbenzo[d]oxazol-2-amine (compound 1) is an anthelmintic activity and lower cytotoxicity against T. spiralis adult worm. N-Methylbenzo[d]oxazol-2-amine up-regulates the metabolism of purine, pyrimidine and down-regulates sphingolipid metabolism .
|
-
-
- HY-N10368
-
|
Parasite
|
Infection
Neurological Disease
Inflammation/Immunology
|
Shinjulactone M is a quassinoid isolated from various parts of Ailanthus species. Ailanthus, an important genus of the Simaroubaceae family, can be used as an febrifuge (antimalarial) and anthelmintic, and is given for the research of chronic bronchitis, epilepsy and asthma .
|
-
-
- HY-W265961
-
ST1859; 1,1′-Methylenedi-2-naphthol
|
Amyloid-β
|
Neurological Disease
Inflammation/Immunology
|
Squoxin (ST1859) is an antiamyloid agent that specifically binds to Aβ1-42 and prevents the aggregation and fibril formation of Aβ. Squoxin crosses the blood-brain barrier (BBB) and has anthelmintic activity and anti-inflammatory properties .
|
-
-
- HY-158423
-
|
Mitochondrial Metabolism
Parasite
|
Infection
|
NPD8790 is a species selective mitochondrial respiratory complex I inhibitor with an IC50 of 2.4 µM for C. elegans complex I. NPD8790 is more selective for nematode species mitochondria than human, bovine, and mouse mitochondria. NPD8790 is an anthelmintic that kills adult soil-transmitted helminths .
|
-
-
- HY-W099479
-
Ethyl butylacetylaminopropionate; IR-3535
|
Reactive Oxygen Species
Apoptosis
|
Cardiovascular Disease
Inflammation/Immunology
|
Insect repellent M 3535 (Ethyl butylacetylaminopropionate; IR-3535) is a novel potent anthelmintic that is toxic to zebrafish with a lethal concentration 50 (LC50) of 140 mg/L at 72 hours post fertilization (hpf). Insect repellent M 3535 causes morphological abnormalities and cardiac defects in early embryonic development of zebrafish by potentially inducing the production and accumulation of reactive oxygen species (Reactive Oxygen Species) and activating oxidative stress responses, thereby activating the endogenous apoptosis pathway .
|
-
-
- HY-B0986
-
4-Hexylresorcinol
|
Parasite
Bacterial
Apoptosis
Glucosidase
Endogenous Metabolite
|
Infection
Metabolic Disease
Cancer
|
Hexylresorcinol (4-Hexylresorcinol) is a natural compound found in plants with antimicrobial, anthelmintic, antiseptic and antitumor activities. Hexylresorcinol can induce apoptosis in squamous carcinoma cells. Hexylresorcinol is a reversible and noncompetitive inhibitor of α-glucosidase. Hexylresorcinol has protective effects against oxidative DNA damage .
|
-
-
- HY-B0217
-
Nitazoxanide
Maximum Cited Publications
11 Publications Verification
NTZ; NSC 697855
|
Parasite
Influenza Virus
Autophagy
|
Infection
Cancer
|
Nitazoxanide (NTZ), an anthelmintic agent, exhibits a broad spectrum of activities against a wide variety of helminths, protozoa, and enteric bacteria infecting animals and humans. Nitazoxanide inhibits Giardia lamblia trophozoite proliferation in axenic culture with an IC50 of 2.4 μM . Nitazoxanide can be used for the research of parasitic gastroenteritis. Nitazoxanide shows anti-Japanese encephalitis virus (JEV) activity in a mouse model .
|
-
-
- HY-121618
-
|
GABA Receptor
Reactive Oxygen Species
Parasite
Apoptosis
Autophagy
|
Infection
Neurological Disease
Cancer
|
α-Thujone is a monoterpene isolated from Thuja occidentalis essential oil with potent anti-tumor activities. α-Thujone is a reversible modulator of the GABA type A receptor and the IC50 for α-Thujone is 21 μM in suppressing the GABA-induced currents. α-Thujone induces ROS accumulation-dependent cytotoxicity, also induces cell apoptosis and autophagy. α-Thujone has antinociceptive, insecticidal, and anthelmintic activity, and easily penetrates the blood-brain barrier .
|
-
-
- HY-B0294
-
|
Parasite
Microtubule/Tubulin
STAT
MDM-2/p53
Apoptosis
Autophagy
|
Infection
Cancer
|
Flubendazole is an anthelmintic drug based on altering microtubule structure, inhibition of tubulin polymerization and disruption of microtubule function. Flubendazole induces apoptosis in human colorectal cancer (CRC) by blocking the STAT3 signaling axis and activation of autophagy. Flubendazole induces P53 expression and reduced Cyclin B1 and p-cdc2 expression. Flubendazole is an antitumor agent. Flubendazole can be used for worm and intestinal parasites .
|
-
-
- HY-B0986R
-
|
Parasite
Bacterial
Apoptosis
Glucosidase
Endogenous Metabolite
|
Infection
Metabolic Disease
Cancer
|
Hexylresorcinol (Standard) is the analytical standard of Hexylresorcinol. This product is intended for research and analytical applications. Hexylresorcinol (4-Hexylresorcinol) is a natural compound found in plants with antimicrobial, anthelmintic, antiseptic and antitumor activities. Hexylresorcinol can induce apoptosis in squamous carcinoma cells. Hexylresorcinol is a reversible and noncompetitive inhibitor of α-glucosidase. Hexylresorcinol has protective effects against oxidative DNA damage .
|
-
-
- HY-B0217R
-
|
Parasite
Influenza Virus
Autophagy
|
Infection
Cancer
|
Nitazoxanide (Standard) is the analytical standard of Nitazoxanide. This product is intended for research and analytical applications. Nitazoxanide (NTZ), an anthelmintic agent, exhibits a broad spectrum of activities against a wide variety of helminths, protozoa, and enteric bacteria infecting animals and humans. Nitazoxanide inhibits Giardia lamblia trophozoite proliferation in axenic culture with an IC50 of 2.4 μM . Nitazoxanide can be used for the research of parasitic gastroenteritis. Nitazoxanide shows anti-Japanese encephalitis virus (JEV) activity in a mouse model .
|
-
-
- HY-127156
-
Anthelmycin
|
Bacterial
|
Infection
|
Hikizimycin is a potent anthelmintic and antibacterial natural product.
|
-
-
- HY-B0294R
-
|
Parasite
Microtubule/Tubulin
STAT
MDM-2/p53
Apoptosis
Autophagy
|
Infection
Cancer
|
Flubendazole (Standard) is the analytical standard of Flubendazole. This product is intended for research and analytical applications. Flubendazole is an anthelmintic drug based on altering microtubule structure, inhibition of tubulin polymerization and disruption of microtubule function. Flubendazole induces apoptosis in human colorectal cancer (CRC) by blocking the STAT3 signaling axis and activation of autophagy. Flubendazole induces P53 expression and reduced Cyclin B1 and p-cdc2 expression. Flubendazole is an antitumor agent. Flubendazole can be used for worm and intestinal parasites .
|
-
-
- HY-118494
-
|
Parasite
|
Infection
|
Ascaridole is an anthelmintic and also has antimalarial activity .
|
-
-
- HY-119556
-
|
Parasite
|
Infection
|
Butonate is an insecticide. Butonate is an orally active anthelmintic .
|
-
-
- HY-124485
-
|
Parasite
|
Infection
|
Nitroscanate is an anthelmintic that has a calming effect on animals .
|
-
-
- HY-B1073
-
|
Parasite
|
Infection
|
Morantel tartrate is a broad spectrum anthelmintic, effective and low toxicity.
|
-
-
- HY-B0413
-
|
Parasite
HIF/HIF Prolyl-Hydroxylase
Microtubule/Tubulin
Antibiotic
|
Infection
Cancer
|
Fenbendazole is an orally active benzimidazole anthelmintic agent, with a broad antiparasitic range. Fenbendazole is a microtubule destabilizing agent and acts on helminthes primarily by binding to tubulin and disrupting the tubulin microtubule equilibrium. Fenbendazole stabilizes the transcriptional activator HIF-1α. Fenbendazole possesses an efficient anti-proliferative activity and induces apoptosis. Fenbendazole causes cell-cycle arrest and mitotic cell death, and has antitumor activity in mice xenografted with wild-type p53 .
|
-
-
- HY-B0244S
-
-
-
- HY-101476
-
Bay 44-4400
|
Parasite
|
Infection
|
Emodepside (PF 1022-221) is a cyclooctadepsipeptide with broad-spectrum anthelmintic activity.
|
-
-
- HY-U00295
-
Melarsonic acid
|
Parasite
|
Infection
|
Melarsonyl (Melarsonic acid) is an anthelmintic agent which can inhibit parasite potently.
|
-
-
- HY-B1313
-
|
Parasite
|
Infection
|
Lobendazole is a potent anthelmintic. Lobendazole inhibits Giardia intestinalis strains .
|
-
-
- HY-125159
-
PF-00520904
|
Parasite
|
Infection
|
Derquantel is a potent anthelmintic. Derquantel causes flaccid paralysis and expulsion of nematodes .
|
-
-
- HY-B0413R
-
|
Parasite
HIF/HIF Prolyl-Hydroxylase
Microtubule/Tubulin
Antibiotic
|
Infection
|
Fenbendazole (Standard) is the analytical standard of Fenbendazole. This product is intended for research and analytical applications. Fenbendazole is an orally active benzimidazole anthelmintic agent, with a broad antiparasitic range. Fenbendazole is a microtubule destabilizing agent and acts on helminthes primarily by binding to tubulin and disrupting the tubulin microtubule equilibrium. Fenbendazole stabilizes the transcriptional activator HIF-1α. Fenbendazole possesses an efficient anti-proliferative activity and induces apoptosis. Fenbendazole causes cell-cycle arrest and mitotic cell death, and has antitumor activity in mice xenografted with wild-type p53 .
|
-
-
- HY-N8484
-
|
Parasite
|
Infection
|
Eprinomectin B1b is a minor component and belongs to the avermectin family of insecticides and anthelmintics.
|
-
-
- HY-B2186
-
|
Parasite
|
Infection
|
Piperazine adipate is a potent broad spectrum anthelmintic against many common worm infections in mammals.
|
-
-
- HY-U00295A
-
Melarsonic acid dipotassium
|
Parasite
|
Infection
|
Melarsonyl dipotassium (Melarsonic acid dipotassium) is an anthelmintic agent which can inhibit parasite potently .
|
-
- HY-123693
-
|
Others
|
Inflammation/Immunology
|
ML358 is a first in class, potent, and selective inhibitor of the SKN-1 pathway (IC50=0.24 μM). ML358 sensitizes the model nematode C. elegans to oxidants and anthelmintic. ML358 potentially used as adjuvants to increase the efficacy and useful life of current anthelmintics .
|
-
- HY-12639
-
|
Parasite
|
Infection
|
Bephenium is an anthelmintic agent formerly used in the treatment of hookworm infections and ascariasis; B-type AChR activator.
|
-
- HY-12785S
-
Ricobendazole d3; Albendazole oxide d3
|
Parasite
|
Inflammation/Immunology
|
Albendazole sulfoxide-d3 is deuterium labeled Albendazole sulfoxide, which is a broad-spectrum anthelmintic.
|
-
- HY-164052
-
|
Parasite
|
Infection
|
Antiparasitic agent-23 (compound 14) is an anthelmintic and insecticide that inhibits insect or helminth parasitism .
|
-
- HY-12639A
-
|
Parasite
|
Infection
|
Bephenium hydroxynaphthoate is an anthelmintic agent formerly used in the treatment of hookworm infections and ascariasis; B-type AChR activator.
|
-
- HY-N0337
-
-
- HY-13666
-
(-)-Tetramisole hydrochloride
|
Parasite
HSV
|
Infection
Neurological Disease
Cancer
|
Levamisole ((-)-Tetramisole) hydrochloride is an anthelmintic and immunomodulator belonging to a class of synthetic imidazothiazole derivatives. Levamisole hydrochloride has antiviral effects against HSV.
|
-
- HY-14774
-
AAD1566
|
nAChR
|
Cancer
|
Monepantel is organic anthelmintic, and acts as a positive allosteric modulator of a nematode-specific clade of nicotinic acetylcholine receptor (nAChR) subunits.
|
-
- HY-115364
-
SKF 29044
|
Microtubule/Tubulin
Parasite
|
Infection
|
Parbendazole is a potent inhibitor of microtubule assembly, destabilizes tubulin, with an EC50 of 530?nM, and exhibits a broad-spectrum anthelmintic activity.
|
-
- HY-B0294S
-
|
Parasite
Microtubule/Tubulin
Apoptosis
|
Infection
Cancer
|
Flubendazole-d3 is the deuterium labeled Flubendazole. Flubendazole is a safe and efficacious anthelmintic agent, which is widely used for anthelmintic to human, rodents and ruminants. Flubendazole exerts anticancer activities by mechanisms including inhibition of microtubule function. Flubendazole induces p53-mediated apoptosis and arrests G2/M cell cycle[1][2].
|
-
- HY-121477
-
|
Parasite
|
Infection
|
Resorantel is an anthelmintic . Resorantel is used in the research of paramphistomiasis in cattle and sheep and has also been used for the research of G. aegypticus .
|
-
- HY-B0263R
-
Tiabendazole (Standard); 2-(4-Thiazolyl)benzimidazole (Standard)
|
Mitochondrial Metabolism
Parasite
|
Infection
|
Thiabendazole (Standard) is the analytical standard of Thiabendazole. This product is intended for research and analytical applications. Thiabendazole inhibits worm-specific fumarate reductase and has anthelmintic properties.
|
-
- HY-17597R
-
|
Parasite
|
Infection
|
Febantel (Standard) is the analytical standard of Febantel. This product is intended for research and analytical applications. Febantel is an anthelmintic used for roundworm and tapeworm infections in poultry and livestock.
|
-
- HY-101476R
-
|
Parasite
|
Infection
|
Emodepside (Standard) is the analytical standard of Emodepside. This product is intended for research and analytical applications. Emodepside (PF 1022-221) is a cyclooctadepsipeptide with broad-spectrum anthelmintic activity.
|
-
- HY-B0299
-
|
Parasite
Apoptosis
|
Infection
Cancer
|
Oxibendazole is an effective benzimidazole anthelmintic and is against nema-tode infections. Oxibendazole can induces apoptosis and has anti-cancer and anti-inflammation activities .
|
-
- HY-N0337S
-
-
- HY-115364S
-
-
- HY-17592
-
|
Parasite
Bacterial
|
Infection
Cancer
|
Bithionol is an antibacterial, anthelmintic, and algaecide agent. Bithionol is also a potent inhibitor of soluble adenylyl cyclase through binding to the allosteric activator site (IC50: 4 μM) .
|
-
- HY-14774S
-
|
nAChR
|
Cancer
|
(Rac)-Monepantel-d5 is deuterium labeled Monepantel. Monepantel is organic anthelmintic, and acts as a positive allosteric modulator of a nematode-specific clade of nicotinic acetylcholine receptor (nAChR) subunits.
|
-
- HY-14774S1
-
|
nAChR
|
Cancer
|
(Rac)-Monepantel sulfone-d5 is deuterium labeled Monepantel. Monepantel is organic anthelmintic, and acts as a positive allosteric modulator of a nematode-specific clade of nicotinic acetylcholine receptor (nAChR) subunits.
|
-
- HY-115364R
-
SKF 29044 (Standard)
|
Microtubule/Tubulin
Parasite
|
Infection
|
Parbendazole (Standard) is the analytical standard of Parbendazole. This product is intended for research and analytical applications. Parbendazole is a potent inhibitor of microtubule assembly, destabilizes tubulin, with an EC50 of 530 nM, and exhibits a broad-spectrum anthelmintic activity.
|
-
- HY-N0337R
-
-
- HY-B2186R
-
|
Parasite
|
Infection
|
Piperazine adipate (Standard) is the analytical standard of Piperazine adipate. This product is intended for research and analytical applications. Piperazine adipate is a potent broad spectrum anthelmintic against many common worm infections in mammals.
|
-
- HY-17594
-
|
Oxidative Phosphorylation
Parasite
Bacterial
Fungal
|
Infection
|
Oxyclozanide is an orally active salicylanilide anthelmintic agent that mainly acts by uncoupling oxidative phosphorylation in flukes. Oxyclozanide shows good anti-adenovirus, anti-biofilm, antifungal, and antibacterial activity .
|
-
- HY-13666S
-
(-)-Tetramisole-d5 (hydrochloride)
|
Parasite
HSV
|
Infection
Neurological Disease
|
Levamisole-d5 (hydrochloride) is the deuterium labeled Levamisole hydrochloride. Levamisole ((-)-Tetramisole) hydrochloride is an anthelmintic and immunomodulator belonging to a class of synthetic imidazothiazole derivatives. Levamisole hydrochloride has antiviral effects against HSV[1][2].
|
-
- HY-147003
-
|
Parasite
|
Infection
|
MMV687807 is an anthelmintic agent which has a good activity against Toxoplasma gondii (T. gondii) with an IC50 value of 0.15 μM and a CC50 value of 1.69 μM .
|
-
- HY-108387
-
|
Parasite
|
Infection
|
Morantel citrate is a veterinary anthelmintic agent that inhibits parasitic infections in cattle, sheep and goats. Morantel citrate paralyzes the nervous system of the parasite, helping the animal expel the dead parasite from the body .
|
-
- HY-13666R
-
|
Parasite
HSV
|
Infection
Neurological Disease
|
Levamisole (hydrochloride) (Standard) is the analytical standard of Levamisole (hydrochloride). This product is intended for research and analytical applications. Levamisole ((-)-Tetramisole) hydrochloride is an anthelmintic and immunomodulator belonging to a class of synthetic imidazothiazole derivatives. Levamisole hydrochloride has antiviral effects against HSV.
|
-
- HY-14774R
-
|
nAChR
|
Cancer
|
Monepantel (Standard) is the analytical standard of Monepantel. This product is intended for research and analytical applications. Monepantel is organic anthelmintic, and acts as a positive allosteric modulator of a nematode-specific clade of nicotinic acetylcholine receptor (nAChR) subunits.
|
-
- HY-Y0055S
-
|
Antibiotic
Fungal
Bacterial
|
Infection
Neurological Disease
|
Phenothiazine-d8 is the deuterium labeled Phenothiazine. Phenothiazine is an antibiotic which has insecticidal, fungicidal, antibacterial and anthelmintic activities. Phenothiazine also can be used for the research of neurological diseases[1][2].
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- HY-147360
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nAChR
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Infection
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Tribendimidine is an orally active, broad-spectrum anthelmintic agent, with particularly high activity against A. lumbricoides and N. americanus. Tribendimidine is also an L-type nicotinic acetylcholine receptor (nAChR) agonist .
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- HY-134220
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Parasite
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Infection
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Doramectin monosaccharide is an acid degradation product of Doramectin (HY-17035), a disaccharide-containing anthelmintic that potentiates glutamate- and GABA-gated chloride channel opening in nematodes. Doramectin undergoes acid-catalyzed hydrolysis to form doramectin monosaccharide.
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- HY-117375
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Parasite
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Infection
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Brotianide is a potent anti-parasitic agent. Brotianide can be used to study liver fluke and gastric fluke infestations .
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- HY-B0299R
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Parasite
Apoptosis
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Infection
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Oxibendazole (Standard) is the analytical standard of Oxibendazole. This product is intended for research and analytical applications. Oxibendazole is an effective benzimidazole anthelmintic and is against nema-tode infections. Oxibendazole can induces apoptosis and has anti-cancer and anti-inflammation activities .
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- HY-W686763
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2,4,6-Triacetylphloroglucinol
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Others
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Infection
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Triacetylphloroglucinol (2,4,6-Triacetylphloroglucinol) is a C3-symmetric three-dimensional bridged ligand. It has been used in the synthesis of various compounds including trinuclear vanadium Schiff base complexes, copper complexes and anthelmintics.
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- HY-17592R
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Parasite
Bacterial
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Infection
Cancer
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Bithionol (Standard) is the analytical standard of Bithionol. This product is intended for research and analytical applications. Bithionol is an antibacterial, anthelmintic, and algaecide agent. Bithionol is also a potent inhibitor of soluble adenylyl cyclase through binding to the allosteric activator site (IC50: 4 μM) .
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- HY-12641A
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nAChR
Parasite
Antibiotic
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Infection
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Pyrantel is an orally active anthelmintic and an agonist of the nicotinic acetylcholine receptor (nAChR). Pyrantel can cause spasmodic muscle paralysis in parasites. Pyrantel can be used in the study of parasitic infections such as ascariasis, hookworm infections, intestinal worms (pinworm infections), trichinosis and trichinosis .
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- HY-123305S
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- HY-17594R
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Oxidative Phosphorylation
Parasite
Bacterial
Fungal
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Infection
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Oxyclozanide (Standard) is the analytical standard of Oxyclozanide. This product is intended for research and analytical applications. Oxyclozanide is an orally active salicylanilide anthelmintic agent that mainly acts by uncoupling oxidative phosphorylation in flukes. Oxyclozanide shows good anti-adenovirus, anti-biofilm, antifungal, and antibacterial activity .
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- HY-12641
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Parasite
nAChR
Antibiotic
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Infection
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Pyrantel tartrate is an orally active anthelmintic and an agonist of the nicotinic acetylcholine receptor (nAChR). Pyrantel tartrate can cause spasmodic muscle paralysis in parasites. Pyrantel tartrate can be used in the study of parasitic infections such as ascariasis, hookworm infections, intestinal worms (pinworm infections), trichinosis and trichinosis .
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- HY-12640
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Pyrantel embonate
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Parasite
nAChR
Antibiotic
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Infection
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Pyrantel pamoate (Pyrantel embonate) is an orally active anthelmintic and an agonist of the nicotinic acetylcholine receptor (nAChR). Pyrantel pamoate can cause spasmodic muscle paralysis in parasites. Pyrantel pamoate can be used in the study of parasitic infections such as ascariasis, hookworm infections, intestinal worms (pinworm infections), trichinosis and trichinosis .
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- HY-A0106
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(-)-Tetramisole
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nAChR
Parasite
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Infection
Inflammation/Immunology
Cancer
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Levamisole ((-)-Levamisole), an anthelmintic agent with immunomodulatory properties. Levamisole acts as a positive allosteric modulator (PAM) for the α3β2 (EC50=300 μM) and α3β4 (EC50=100 μM) subtype of nAChRs. Orally active .
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- HY-B0777
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CL301423
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Antibiotic
BCRP
P-glycoprotein
Parasite
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Infection
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Moxidectin (CL301423) is an orally active macrolide (ML) anthelmintic for the prevention and control of heartworms and roundworms. Moxidectin is also a substrate of BCRP and P-glycoprotein (P-gp) in vivo, and is secreted into breast milk and effluxed from the host and parasite mediated by Bcrp1 and P-gp. This may be related to the presence of chemical residues in milk .
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- HY-B0497S1
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BAY2353-13C6
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Isotope-Labeled Compounds
STAT
Parasite
Antibiotic
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Infection
Cancer
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Niclosamide- 13C6 is the 13C6 labeled Niclosamide. Niclosamide (BAY2353) is an orally bioavailable chlorinated salicylanilide, with anthelmintic and potential antineoplastic activity. Niclosamide (BAY2353) inhibits STAT3 with IC50 of 0.25 μM in HeLa cells and inhibits DNA replication in a cell-free assay.
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- HY-126057S
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Parasite
5-HT Receptor
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Infection
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(R)-Praziquantel-d11 is the deuterium labeled (R)-Praziquantel. (R)-Praziquantel, the active enantiomer of Praziquantel, is a partial agonist of the human 5-HT2B receptor. (R)-Praziquantel acts as an antischistosomal eutomer[1].
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- HY-126057
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Parasite
5-HT Receptor
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Infection
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(R)-Praziquantel, the active enantiomer of Praziquantel, is a partial agonist of the human 5-HT2B receptor. (R)-Praziquantel acts as an antischistosomal eutomer .
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- HY-N3014
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Notch
Apoptosis
Parasite
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Infection
Cancer
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Bruceine D is a Notch inhibitor with anti-cancer activity and induces apoptosis in several human cancer cells. Bruceine D is an effective botanical insect antifeedant with outstanding systemic properties, causing potent pest growth inhibitory activity . Bruceine D has strong anthelmintic activity against D. intermedius with an EC50 value of 0.57 mg/L .
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- HY-A0106R
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nAChR
Parasite
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Infection
Inflammation/Immunology
Cancer
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Levamisole (Standard) is the analytical standard of Levamisole. This product is intended for research and analytical applications. Levamisole ((-)-Levamisole), an anthelmintic agent with immunomodulatory properties. Levamisole acts as a positive allosteric modulator (PAM) for the α3β2 (EC50=300 μM) and α3β4 (EC50=100 μM) subtype of nAChRs. Orally active .
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- HY-12641R
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Parasite
nAChR
Antibiotic
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Infection
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Pyrantel (tartrate) (Standard) is the analytical standard of Pyrantel (tartrate). This product is intended for research and analytical applications. Pyrantel tartrate is an orally active anthelmintic and an agonist of the nicotinic acetylcholine receptor (nAChR). Pyrantel tartrate can cause spasmodic muscle paralysis in parasites. Pyrantel tartrate can be used in the study of parasitic infections such as ascariasis, hookworm infections, intestinal worms (pinworm infections), trichinosis and trichinosis .
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- HY-77813
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Bacterial
Apoptosis
Antibiotic
Parasite
Autophagy
Reactive Oxygen Species
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Infection
Endocrinology
Cancer
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Benzyl isothiocyanate is an orally available isothiocyanate with bactericidal, anticancer, antiangiogenic and anthelmintic activities. Benzyl isothiocyanate exerts anticancer functions by regulating multiple signaling pathways, including apoptosis, cell proliferation, cell cycle arrest, metastasis, angiogenesis, and autophagy. In addition, Benzyl isothiocyanate can enhance muscle insulin sensitivity to improve obesity-induced hyperglycemia .
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- HY-12640R
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Pyrantel embonate (Standard)
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Parasite
nAChR
Antibiotic
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Infection
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Pyrantel (pamoate) (Standard) is the analytical standard of Pyrantel (pamoate). This product is intended for research and analytical applications. Pyrantel pamoate (Pyrantel embonate) is an orally active anthelmintic and an agonist of the nicotinic acetylcholine receptor (nAChR). Pyrantel pamoate can cause spasmodic muscle paralysis in parasites. Pyrantel pamoate can be used in the study of parasitic infections such as ascariasis, hookworm infections, intestinal worms (pinworm infections), trichinosis and trichinosis .
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- HY-B0777R
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CL301423 (Standard)
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Antibiotic
BCRP
P-glycoprotein
Parasite
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Infection
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Moxidectin (Standard) is the analytical standard of Moxidectin. This product is intended for research and analytical applications. Moxidectin (CL301423) is an orally active macrolide (ML) anthelmintic for the prevention and control of heartworms and roundworms. Moxidectin is also a substrate of BCRP and P-glycoprotein (P-gp) in vivo, and is secreted into breast milk and effluxed from the host and parasite mediated by Bcrp1 and P-gp. This may be related to the presence of chemical residues in milk .
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- HY-130484
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Parasite
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Infection
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2,3-Dehydro-3,4-dihydro ivermectin is an analog of ivermectin (HY-15310) and an anthelmintic. 2,3-Dehydro-3,4-dihydro ivermectin has activity against L. amazonensis promastigotes and amastigotes (IC50s=13.8 and 3.6 µM, respectively) without inducing cytotoxicity to macrophages (IC50= 65.5 µM).
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- HY-N8280
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Fungal
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Infection
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IKD-8344 is a macrocyclic dilactone originally isolated from an actinomycete species and has diverse biological activities, including anticancer, antimicrobial, and anthelmintic properties. It is cytotoxic to L5178Y murine leukemia cells (IC50=0.54 ng/ml).1 IKD-8344 inhibits growth of the mycelial form of C. albicans (MIC=6.25 μg/mL) and potentiates the activity of polymyxin B against the multidrug-resistant pathogenic bacterium B. cenocepacia.
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- HY-17592A
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Parasite
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Infection
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Bithionol sulfoxide is an anti-infection agent for parasites. Bithionol sulfoxide has mutagenic activity. Bithionol sulfoxide can be used in the research of parasite infection, such as paragonimiasis, flukes andcestodes infection .
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- HY-W714137
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Lesquerellin; 6-Methylthiohexyl isothiocyanate
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Bacterial
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Infection
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(6-Isothiocyanatohexyl)(methyl)sulfane (Lesquerellin; 6-Methylthiohexyl isothiocyanate) is an isothiocyanate found in wasabi (W. japonica) and has various biological activities. (6-Isothiocyanatohexyl)(methyl)sulfane is active against the bacterium Bacillus subtilis and the fungus T. mentagrophytes (MIC=25 μg/mL). (6-Isothiocyanatohexyl)(methyl)sulfane also has anthelmintic activity against blue mussel (M. edulis). (6-Isothiocyanatohexyl)(methyl)sulfane has antifouling activity when applied to polyvinyl chloride (PVC) panels at a concentration of 50 μmol/cm2 in a conventional immersion test.
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- HY-B0263
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Cat. No. |
Product Name |
Type |
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- HY-B1636
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Dyes
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Dithiazanine iodide is an effective broad-spectrum anthelmintic. Dithiazanine iodide can be used for the research of trichuriasis, strongyloidiasis, enterobiasis, ascariasis, and hookworm infection. Dithiazanine iodide is also a cyanine dye .
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Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
Cat. No. |
Product Name |
Chemical Structure |
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- HY-B0244S
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Praziquantel-d11 is the deuterium labeled Praziquantel, which is an anthelmintic.
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- HY-12785S
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Albendazole sulfoxide-d3 is deuterium labeled Albendazole sulfoxide, which is a broad-spectrum anthelmintic.
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- HY-B0294S
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Flubendazole-d3 is the deuterium labeled Flubendazole. Flubendazole is a safe and efficacious anthelmintic agent, which is widely used for anthelmintic to human, rodents and ruminants. Flubendazole exerts anticancer activities by mechanisms including inhibition of microtubule function. Flubendazole induces p53-mediated apoptosis and arrests G2/M cell cycle[1][2].
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- HY-N0337S
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Eugenol-d3 is the deuterium labeled Eugenol. Eugenol is an essential oil found in cloves with antibacterial, anthelmintic and antioxidant activity. Eugenol is shown to inhibit lipid peroxidation.
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- HY-14774S
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(Rac)-Monepantel-d5 is deuterium labeled Monepantel. Monepantel is organic anthelmintic, and acts as a positive allosteric modulator of a nematode-specific clade of nicotinic acetylcholine receptor (nAChR) subunits.
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- HY-14774S1
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(Rac)-Monepantel sulfone-d5 is deuterium labeled Monepantel. Monepantel is organic anthelmintic, and acts as a positive allosteric modulator of a nematode-specific clade of nicotinic acetylcholine receptor (nAChR) subunits.
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- HY-Y0055S
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Phenothiazine-d8 is the deuterium labeled Phenothiazine. Phenothiazine is an antibiotic which has insecticidal, fungicidal, antibacterial and anthelmintic activities. Phenothiazine also can be used for the research of neurological diseases[1][2].
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- HY-115364S
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Parbendazole-d3 is the deuterium labeled Parbendazole. Parbendazole is a potent inhibitor of microtubule assembly, destabilizes tubulin, with an EC50 of 530 nM, and exhibits a broad-spectrum anthelmintic activity.
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- HY-13666S
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Levamisole-d5 (hydrochloride) is the deuterium labeled Levamisole hydrochloride. Levamisole ((-)-Tetramisole) hydrochloride is an anthelmintic and immunomodulator belonging to a class of synthetic imidazothiazole derivatives. Levamisole hydrochloride has antiviral effects against HSV[1][2].
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-
- HY-123305S
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5-Hydroxymebendazole-d3 is a deuterium labeled 5-Hydroxymebendazole. 5-Hydroxymebendazole is the one metabolite of Benzimidazoles[1].
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- HY-B0497S1
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Niclosamide- 13C6 is the 13C6 labeled Niclosamide. Niclosamide (BAY2353) is an orally bioavailable chlorinated salicylanilide, with anthelmintic and potential antineoplastic activity. Niclosamide (BAY2353) inhibits STAT3 with IC50 of 0.25 μM in HeLa cells and inhibits DNA replication in a cell-free assay.
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-
-
- HY-126057S
-
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(R)-Praziquantel-d11 is the deuterium labeled (R)-Praziquantel. (R)-Praziquantel, the active enantiomer of Praziquantel, is a partial agonist of the human 5-HT2B receptor. (R)-Praziquantel acts as an antischistosomal eutomer[1].
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Cat. No. |
Product Name |
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Classification |
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- HY-N0337
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Flavoring Agents
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Eugenol is an essential oil found in cloves with antibacterial, anthelmintic and antioxidant activity. Eugenol is shown to inhibit lipid peroxidation.
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