2. Anti-infection
  3. Parasite
  4. Melarsonyl

Melarsonyl (Melarsonic acid) is an anthelmintic agent which can inhibit parasite potently.

For research use only. We do not sell to patients.

Melarsonyl Chemical Structure

Melarsonyl Chemical Structure

CAS No. : 37526-80-0

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Other Forms of Melarsonyl:

Melarsonyl Related Antibodies

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Amebae Coccidia Leishmania Mite Plasmodium Toxoplasma Trypanosoma Schistosome

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  • References

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Description

Melarsonyl (Melarsonic acid) is an anthelmintic agent which can inhibit parasite potently.

IC50 & Target

Parasite[1]
In Vivo

For acute infections produced by T. brucei brucei GVR, Potassium Melarsonyl exhibits trypanocidal activities. Potassium Melarsonyl (Trimelarsan) cures less than 50% mice at a dose of 25 μmol/kg for 4 consecutive days. At 60 μmol/kg, it cures all the mice in a chronic-infection model[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

456.33

Formula

C13H13AsN6O4S2
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C(C1S[As](C2=CC=C(NC3=NC(N)=NC(N)=N3)C=C2)SC1C(O)=O)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Animal Administration
[1]

Mice[1]

Mice are infected i.p. with 104 bloodstream trypomastigotes taken from an infected mouse and suspended in 0.1 mL of phosphate-buffered saline, pH 7.2. The infection is allowed to develop for 24 h before treatment is begun. Ten infected mice are used as controls and received only excipient, 1% carboxymethylcellulose by the i.p. route in a 0.1 ml volume. The other mice receive a single dose of the diluted or suspended Potassium Melarsonyl (20, 40, 60 μmol/kg) in the same manner. Six mice are used per dose. The trypanocidal activity is evaluated by the mean survival time of treated mice for each dose[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
References
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Melarsonyl Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Melarsonyl37526-80-0Melarsonic acidParasiteInhibitorinhibitorinhibit

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