2. Anti-infection
  3. Antibiotic Fungal Bacterial Parasite
  4. Phenothiazine

Phenothiazine  (Synonyms: Thiodiphenylamine)

Cat. No.: HY-Y0055 Purity: 99.80%
COA Handling Instructions

Molarity Calculator

Phenothiazine is an antibiotic which has insecticidal, fungicidal, antibacterial and anthelmintic activities. Phenothiazine also can be used for the research of neurological diseases.

For research use only. We do not sell to patients.

Phenothiazine Chemical Structure

Phenothiazine Chemical Structure

CAS No. : 92-84-2

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Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
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 USD 55 In-stock
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10 mM * 1 mL in DMSO USD 55 In-stock
Solid
500 mg USD 50 In-stock
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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Phenothiazine:

Phenothiazine Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE Phenothiazine

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View All Parasite Isoform Specific Products:

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Amebae Coccidia Leishmania Mite Plasmodium Toxoplasma Trypanosoma Schistosome

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Phenothiazine is an antibiotic which has insecticidal, fungicidal, antibacterial and anthelmintic activities. Phenothiazine also can be used for the research of neurological diseases[1][2].

Molecular Weight

199.27

Formula

C12H9NS
CAS No.
Appearance

Solid

Color

Off-white to light green

SMILES

C12=CC=CC=C1NC3=C(C=CC=C3)S2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 2 years
-20°C 1 year
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (501.83 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.0183 mL 25.0916 mL 50.1832 mL
5 mM 1.0037 mL 5.0183 mL 10.0366 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% Saline

    Solubility: ≥ 2.5 mg/mL (12.55 mM); Clear solution

    This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).

    Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.

    Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
  • Protocol 2

    Add each solvent one by one:  10% DMSO    90% Corn Oil

    Solubility: ≥ 2.5 mg/mL (12.55 mM); Clear solution

    This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.

    Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL Corn oil, and mix evenly.

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
%
DMSO +
% 
+
%
Tween-80 +
%
Saline
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Calculation results:
Working solution concentration: mg/mL
Method for preparing stock solution: mg drug dissolved in μL  DMSO (Stock solution concentration: mg/mL).
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).
Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.
 If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation

Purity: 99.80%

COA (250 KB) HNMR (116 KB) RP-HPLC (262 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 5.0183 mL 25.0916 mL 50.1832 mL 125.4579 mL
5 mM 1.0037 mL 5.0183 mL 10.0366 mL 25.0916 mL
10 mM 0.5018 mL 2.5092 mL 5.0183 mL 12.5458 mL
15 mM 0.3346 mL 1.6728 mL 3.3455 mL 8.3639 mL
20 mM 0.2509 mL 1.2546 mL 2.5092 mL 6.2729 mL
25 mM 0.2007 mL 1.0037 mL 2.0073 mL 5.0183 mL
30 mM 0.1673 mL 0.8364 mL 1.6728 mL 4.1819 mL
40 mM 0.1255 mL 0.6273 mL 1.2546 mL 3.1364 mL
50 mM 0.1004 mL 0.5018 mL 1.0037 mL 2.5092 mL
60 mM 0.0836 mL 0.4182 mL 0.8364 mL 2.0910 mL
80 mM 0.0627 mL 0.3136 mL 0.6273 mL 1.5682 mL
100 mM 0.0502 mL 0.2509 mL 0.5018 mL 1.2546 mL
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Phenothiazine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Phenothiazine92-84-2ThiodiphenylamineAntibioticFungalBacterialParasiteinsecticidalfungicidalantibacterialanthelminticneurologicalInhibitorinhibitorinhibit

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