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Pathways Recommended: Stem Cell/Wnt Cell Cycle/DNA Damage
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MR-32 cell.

" in MedChemExpress (MCE) Product Catalog:
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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-168440
    Aurora-A ligand 1

    		Ligands for Target Protein for PROTAC Aurora Kinase Cancer
    Aurora-A ligand 1 is a high-affinity and specific Aurora-A inhibitor with a dissociation constant (Kd) value of 0.85 nM. Aurora-A ligand 1 can serve as a ligand for target protein (Ligands for Target Protein for PROTAC) for the development of PROTAC Aurora-A degraders with antitumor activity. Aurora-A ligand 1 can be used for the synthesis of HLB-0532259 (HY-168439). HLB-0532259 shows anti-tumor activity against neuroblastoma .
    Aurora-A ligand 1

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