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Results for "

WASP

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Antibiotic (1) Arp2/3 Complex (4) Bacterial (3) Endogenous Metabolite (1) Sodium Channel (2)
By Research Areas:	Cancer (2) Endocrinology (1) Infection (4) Metabolic Disease (1) Neurological Disease (3)

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P1045

*187-1, N-WASP* inhibitor** 1 Publications Verification	Arp2/3 Complex	Others
187-1, N-WASP inhibitor, a 14-aa cyclic peptide, is an allosteric neural Wiskott-Aldrich syndrome protein (N-WASP) inhibitor. 187-1, N-WASP inhibitor potently inhibits actin assembly induced by phosphatidylinositol 4,5-bisphosphate (PIP2) with an IC₅₀ of 2 μM. 187-1, N-WASP inhibitor prevents the activation of Arp2/3 complex by N-WASP by stabilizing the autoinhibited state of the protein .

HY-148683

EG-011	Arp2/3 Complex	Cancer
EG-011 is the first-in-class and potent Wiskott-Aldrich syndrome protein (WASP) activator. EG-011 activates the auto-inhibited form of WASP with strong actin polymerization. EG-011 has selective anti-tumor activity in lymphomas .

HY-P1084

β-Pompilidotoxin β-PMTX	Sodium Channel	Neurological Disease
β-Pompilidotoxin (β-PMTX), a wasp venom, can slow sodium channel inactivation and increases steady-state sodium current in cells .

HY-P2705

Mastoparan X	Endogenous Metabolite	Others
Mastoparan X is a GTP-binding regulatory protein (G protein)-activating peptide, and a tetradecapeptide from wasp venom. Mastoparan X acts function by the direct activation of G protein that couple to phospholipase C to cause secretion from various kinds of cells .

HY-P1045A

*187-1, N-WASP* inhibitor TFA**	Arp2/3 Complex	Others
187-1, N-WASP inhibitor TFA, a 14-aa cyclic peptide, is an allosteric neural Wiskott-Aldrich syndrome protein (N-WASP) inhibitor. 187-1, N-WASP inhibitor TFA potently inhibits actin assembly induced by phosphatidylinositol 4,5-bisphosphate (PIP2) with an IC₅₀ of 2 μM. 187-1, N-WASP inhibitor TFA prevents the activation of Arp2/3 complex by N-WASP by stabilizing the autoinhibited state of the protein .

HY-P5722

Peptide 5f	Bacterial	Infection
Peptide 5f is an antimicrobial peptide derived from wasp venom. Peptide 5f has antimicrobial activity against bacteria and fungi. Peptide 5f has little hemolytic activity on human red blood cells .

HY-N12223

Piericidin B	Antibiotic Bacterial	Infection
Piericidin B (compound 8) is an antibiotic that provides strong antibacterial defense for wasp larvae .

HY-P1084A

β-Pompilidotoxin TFA β-PMTX TFA	Sodium Channel	Neurological Disease
β-Pompilidotoxin TFA (β-PMTX TFA), a wasp venom, can slow sodium channel inactivation and increases steady-state sodium current in cells .

HY-W778833

(Z)-11-Octadecen-1-ol	Others	Endocrinology
(Z)-11-Octadecen-1-ol is a marking secretion deposited by wasps on repeated flight paths, isolated from the paired labial glands of North American male bumblebees .

HY-P10518

Anoplin	Bacterial	Infection
Anoplin is an antimicrobial peptide found in the venom of the solitary wasp (Anoplius samariensis). Anoplin exhibits antimicrobial activity against a wide range of bacteria, including both gram-positive and gram-negative bacteria. Anoplin can be used in the development of antibiotics .

HY-12534

Wiskostatin 1 Publications Verification	Arp2/3 Complex	Neurological Disease
Wiskostatin is a potent and selective inhibitor of neuronal Wiskott-Aldrich syndrome protein (N-WASP)-mediated actin polymerization by stabilization of the closed, autoinhibited conformation, thereby preventing Arp2/3 complex activation. Wiskostatin is also a dynamin inhibitor with an IC₅₀ value of 20.7 μM and a potent inhibitor of clathrin-mediated endocytosis with an IC₅₀ value of 6.9 μM. Wiskostatin causes a rapid, profound, and irreversible decrease in cellular ATP levels. Wiskostatin also induces disassembly of podosomes in a murine monocyte cell line .

Cat. No.	Product Name	Target	Research Area

HY-P1045

*187-1, N-WASP* inhibitor** 1 Publications Verification	Arp2/3 Complex	Others
187-1, N-WASP inhibitor, a 14-aa cyclic peptide, is an allosteric neural Wiskott-Aldrich syndrome protein (N-WASP) inhibitor. 187-1, N-WASP inhibitor potently inhibits actin assembly induced by phosphatidylinositol 4,5-bisphosphate (PIP2) with an IC₅₀ of 2 μM. 187-1, N-WASP inhibitor prevents the activation of Arp2/3 complex by N-WASP by stabilizing the autoinhibited state of the protein .

HY-P0246

Mastoparan	Peptides	Metabolic Disease
Mastoparan, a tetradecapeptide which is a component of wasp venom, stimulates release of prolactin from cultured rat anterior pituitary cells.

HY-P1084

β-Pompilidotoxin β-PMTX	Sodium Channel	Neurological Disease
β-Pompilidotoxin (β-PMTX), a wasp venom, can slow sodium channel inactivation and increases steady-state sodium current in cells .

HY-P2705

Mastoparan X	Endogenous Metabolite	Others
Mastoparan X is a GTP-binding regulatory protein (G protein)-activating peptide, and a tetradecapeptide from wasp venom. Mastoparan X acts function by the direct activation of G protein that couple to phospholipase C to cause secretion from various kinds of cells .

HY-P1045A

*187-1, N-WASP* inhibitor TFA**	Arp2/3 Complex	Others
187-1, N-WASP inhibitor TFA, a 14-aa cyclic peptide, is an allosteric neural Wiskott-Aldrich syndrome protein (N-WASP) inhibitor. 187-1, N-WASP inhibitor TFA potently inhibits actin assembly induced by phosphatidylinositol 4,5-bisphosphate (PIP2) with an IC₅₀ of 2 μM. 187-1, N-WASP inhibitor TFA prevents the activation of Arp2/3 complex by N-WASP by stabilizing the autoinhibited state of the protein .

HY-P5722

Peptide 5f	Bacterial	Infection
Peptide 5f is an antimicrobial peptide derived from wasp venom. Peptide 5f has antimicrobial activity against bacteria and fungi. Peptide 5f has little hemolytic activity on human red blood cells .

HY-P1084A

β-Pompilidotoxin TFA β-PMTX TFA	Sodium Channel	Neurological Disease
β-Pompilidotoxin TFA (β-PMTX TFA), a wasp venom, can slow sodium channel inactivation and increases steady-state sodium current in cells .

HY-P5717

Peptide 12d	Peptides	Infection
Peptide 12d is an antimicrobial peptide isolated from the venom of wasp. Peptide 12d mediates antimicrobial response by stimulating mast cell degranulation .

HY-P10518

Anoplin	Bacterial	Infection
Anoplin is an antimicrobial peptide found in the venom of the solitary wasp (Anoplius samariensis). Anoplin exhibits antimicrobial activity against a wide range of bacteria, including both gram-positive and gram-negative bacteria. Anoplin can be used in the development of antibiotics .

HY-P3284

Mastoparan M tetraacetate	Peptides	Cancer
Mastoparan M tetraacetate is a tetrapeptide amide isolated from the Chinese giant hornet (Vespa mandarinia). The amino acid sequence of Mastoparan M tetraacetate shares some structural homology with Mastoparan X, a wasp venom isolated from the Chinese giant hornet as well .

Mastoparan	Structural Classification Natural Products Animals Classification of Application Fields Source classification Metabolic Disease Disease Research Fields	Others
Mastoparan, a tetradecapeptide which is a component of wasp venom, stimulates release of prolactin from cultured rat anterior pituitary cells.

Piericidin B	Structural Classification Alkaloids Microorganisms Source classification Pyridine Alkaloids	Antibiotic Bacterial
Piericidin B (compound 8) is an antibiotic that provides strong antibacterial defense for wasp larvae .

(Z)-11-Octadecen-1-ol	Structural Classification Natural Products Animals Source classification	Others
(Z)-11-Octadecen-1-ol is a marking secretion deposited by wasps on repeated flight paths, isolated from the paired labial glands of North American male bumblebees .

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P81720

	*N WASP* Antibody (YA1465)** NWASP; WASPB; N-WASP	WB, IHC-F, IHC-P, ICC/IF	Human, Mouse
	N WASP Antibody (YA1465) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1465), targeting N WASP, with a predicted molecular weight of 55 kDa (observed band size: 65 kDa). N WASP Antibody (YA1465) can be used for WB, IHC-F, IHC-P, ICC/IF experiment in human, mouse background.

HY-P82794

	WAS Antibody (YA2539) WAS; IMD2; Wiskott-Aldrich syndrome protein; WASP	WB, ICC/IF, IP, FC	Human, Mouse, Rat
	WAS Antibody (YA2539) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2539), targeting WAS, with a predicted molecular weight of 53 kDa (observed band size: 60 kDa). WAS Antibody (YA2539) can be used for WB, ICC/IF, IP, FC experiment in human, mouse, rat background.

HY-P83327

	WAVE 2 Antibody (YA3072) WASF2; WAVE2; Wiskott-Aldrich syndrome protein family member 2; WASP family protein member 2; Protein WAVE-2; Verprolin homology domain-containing protein 2	WB, IHC-P	Human, Mouse, Rat
	WAVE 2 Antibody (YA3072) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3072), targeting WAVE 2, with a predicted molecular weight of 54 kDa (observed band size: 80 kDa). WAVE 2 Antibody (YA3072) can be used for WB, IHC-P experiment in human, mouse, rat background.

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WASP

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