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  2. Bacterial
  3. Anoplin

Anoplin is an antimicrobial peptide found in the venom of the solitary wasp (Anoplius samariensis). Anoplin exhibits antimicrobial activity against a wide range of bacteria, including both gram-positive and gram-negative bacteria. Anoplin can be used in the development of antibiotics.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Anoplin Chemical Structure

Anoplin Chemical Structure

CAS No. : 321352-67-4

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Description

Anoplin is an antimicrobial peptide found in the venom of the solitary wasp (Anoplius samariensis). Anoplin exhibits antimicrobial activity against a wide range of bacteria, including both gram-positive and gram-negative bacteria. Anoplin can be used in the development of antibiotics[1].

Cellular Effect
Cell Line Type Value Description References
4T1 IC50
191.03 μM
Compound: Anoplin
Antiproliferative activity against triple-negative mouse 4T1 cells assessed as inhibition of cell growth measured after 24 hrs by Cell Counting Kit-8 assay
Antiproliferative activity against triple-negative mouse 4T1 cells assessed as inhibition of cell growth measured after 24 hrs by Cell Counting Kit-8 assay
[PMID: 33844923]
B16-F10 IC50
> 400 μM
Compound: Anoplin
Antiproliferative activity against mouse B16-F10 cells assessed as inhibition of cell growth measured after 24 hrs by Cell Counting Kit-8 assay
Antiproliferative activity against mouse B16-F10 cells assessed as inhibition of cell growth measured after 24 hrs by Cell Counting Kit-8 assay
[PMID: 33844923]
Erythrocyte EC50
> 500 μg/mL
Compound: 10
Hemolytic activity in sheep erythrocytes after 1 hr
Hemolytic activity in sheep erythrocytes after 1 hr
[PMID: 23719232]
Molecular Weight

1153.50

Formula

C54H104N16O11

CAS No.
Sequence

Gly-Leu-Leu-Lys-Arg-Ile-Lys-Thr-Leu-Leu-NH2

Sequence Shortening

GLLKRIKTLL-NH2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Anoplin
Cat. No.:
HY-P10518
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