Search Result
Results for "
highly water-soluble
" in MedChemExpress (MCE) Product Catalog:
5
Biochemical Assay Reagents
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-15933
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- HY-125695
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- HY-15913
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Biochemical Assay Reagents
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Others
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DAOS, a Trinder's reagent, is a novel highly water-soluble aniline derivative; are widely used in diagnostic tests and biochemical tests.
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- HY-15918
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Biochemical Assay Reagents
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Others
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HDAOS is a novel Trinder's reagent, which is a highly water-soluble aniline derivative; are widely used in diagnostic tests and biochemical tests.
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- HY-101800
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SNX2-1-165; BCD-115
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CDK
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Cancer
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Senexin B (SNX2-1-165; BCD-115) is a potent, highly water-soluble and bioavailable CDK8/19 inhibitor, with Kds of 140 nM for CDK8 and 80 nM for CDK19.
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- HY-160429
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Drug Derivative
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Others
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PSAR18-COOH is a derivative of PSAR extracted from patent WO2009064913A1. PSAR is a highly hydrophilic, biodegradable, non-immunogenic and water-soluble polymer that has been employed in several delivery systems for drugs or diagnostics.
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- HY-160210
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Adrenergic Receptor
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Cardiovascular Disease
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BAY-6096 is a potent, selective, and highly water-soluble adrenergic receptor α2B antagonist with an IC50 of 14 nM. BAY-6096 can effectively reduceα 2B receptor agonist-induced rat vascular contraction .
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- HY-D0129
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MPTS
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Fluorescent Dye
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Others
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8-Methoxypyrene-1,3,6-trisulfonate trisodium (MPTS) is a highly water-soluble superpolar fluorescent probe .
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- HY-D1367
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Fluorescent Dye
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Sulfo-Cyanine7 carboxylic acid is a highly hydrophilic and water-soluble near-infrared dye. It improves quantum yield in the near-infrared range and has a very high molar extinction coefficient.
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- HY-105064C
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CP-597396 dihydrochloride
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Na+/H+ Exchanger (NHE)
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Cancer
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Zoniporide dihydrochloride (CP-597396 dihydrochloride) is a potent and selective inhibitor of highly water-soluble sodium hydrogen exchange type 1 (NHE-1). Zoniporide dihydrochloride inhibits NHE1 dependent 22Na + uptake in vitro with an IC50 of 14 nM. Zoniporide has antitumor activity .
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- HY-110048
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Cannabinoid Receptor
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Neurological Disease
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O-2545 hydrochloride is a highly potent, water-soluble CB1/CB2 receptor agonist (with Ki values of 1.5 and 0.32 nM for CB1 and CB2 respectively), can be used for epilepsy, pain, multiple sclerosis research .
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- HY-D1376
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Fluorescent Dye
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Sulfo-Cyanine5.5 amine potassium is a water-soluble cyanine dye suitable for far-red/near-infrared applications such as in vivo imaging. The dye has four sulfonate groups, making it highly hydrophilic and water-soluble. Like other cyanines, sulfo-Cyanine5.5 has an excellent extinction coefficient, making it a bright fluorescent marker in the far-red region. This is an amine-containing fluorescent dye. The amine group is separated from the fluorophore by a relatively long linker that facilitates conjugation. Aliphatic primary amine groups can be coupled with various electrophiles (activated esters, epoxides, etc.) and can also be used for enzymatic transamination labeling.
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- HY-151713
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Fluorescent Dye
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Others
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Sulfo-Cy3-Methyltetrazine (figure 7 compound 5) is a click chemistry reagent containing methyltetrazine and a water-soluble dye. Sulfo-Cy3-Methyltetrazine shows good stability at physiological pH. Sulfo-Cy3-Methyltetrazine can be coupled to trans-cyclooctene and is also highly reactive towards cyclooctene .
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- HY-N0322A
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Liposome
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Others
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Cholesterol Water Soluble is a major sterol in mammals, constituting 20-25% of the structural composition of the plasma membrane. The plasma membrane is highly permeable to water but relatively impermeable to ions and protons. Cholesterol Water Soluble plays an important role in determining the fluidity and permeability characteristics of membranes and the function of transporters and signaling proteins. Cholesterol Water Soluble is also an endogenous estrogen-related receptor alpha (ERRα) agonist. Cholesterol Water Soluble can be used to study the effects of cholesterol on potassium currents in inner hair cells .
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- HY-15096
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FJ-776
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Fluorescent Dye
HSP
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Cancer
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MKT-077 (FJ-776), a highly water-soluble mitochondrial dye, has significant antitumor activity . MKT-077 exhibits low cytotoxicity, and inhibits broad-spectrum human cancer cell lines (colon cancer, breast cancer, pancreatic cancer). MKT-077 inhibits the growth of tumor in nude mice enograft tumor model. Ex/Em=488/543 nm .
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- HY-118540
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Diazoresorcinol
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Fluorescent Dye
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Others
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Resazurin (Diazoresorcinol) is a water-soluble, non-toxic, stable, membrane-permeable blue non-fluorescent dye (faintly fluorescent). Resazurin is used as a redox indicator, can be reduced to pink, highly fluorescent Resorufin (Ex=530-560 nm, Em=590 nm) in living cells. Resazurin can be used for the detection of cell viability, toxicity, proliferation, migration and invasion in cells (human, plant and animal, bacterial and fungal) .
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- HY-15932
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TOOS sodium salt
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Biochemical Assay Reagents
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Others
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TOOS (TOOS sodium salt) is a highly water-soluble aniline derivative widely used in diagnostics and biological experiments. TOOS can be combined with 3-methyl-2-benzothiazolinone hydrazone hydrochloride (MBTH) to form a chromogenic system to measure oxidase activity. In the MBTH-TOOS chromogenic system, MBTH is catalytically oxidized to produce (-NH) free radicals, which react with TOOS to form colorless compounds. Furthermore, the colorless compound undergoes a disproportionation reaction to produce a blue-violet quinoid compound .
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- HY-111474
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Myosin
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Cardiovascular Disease
Neurological Disease
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Para-aminoblebbistatin is a highly water soluble, non-fluorescent and photostable C15 amino-substituted derivative of blebbistatin; inhibits various (myosin II) isoforms both in vitro and in vivo.
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- HY-W019883
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Biochemical Assay Reagents
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Others
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Dipotassium hydrogen phosphate is a highly water-soluble salt which is often used as a fertilizer, food additive and buffering agent. Dipotassium hydrogen phosphate can be used as an excipient, such as pH regulator, buffer. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .
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- HY-153725
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Liposome
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Cancer
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17:1 Lyso PC is a liposome to simulate biological phospholipid membrane. Liposomes are the main component of vesicles with concentric phospholipid bilayer membranes, which can be used to construct drug delivery systems for anti-cancer and anti-infection fields. Highly polar water-soluble payloads can be trapped in the internal aqueous space of liposomes, while lipophilic payloads can partition into and become part of the lipid bilayer. Especially for delivering antisense oligonucleotides, it can overcome problems such as inefficient cellular uptake and rapid loss in the body .
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- HY-W591449
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Liposome
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Cancer
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DOPE-PEG-Azide, MW 2000 is a liposome to simulate biological phospholipid membrane. Liposomes are the main component of vesicles with concentric phospholipid bilayer membranes, which can be used to construct drug delivery systems for anti-cancer and anti-infection fields. Highly polar water-soluble payloads can be trapped in the internal aqueous space of liposomes, while lipophilic payloads can partition into and become part of the lipid bilayer. Especially for delivering antisense oligonucleotides, it can overcome problems such as inefficient cellular uptake and rapid loss in the body .
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- HY-40118
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Boc-L-proline methyl ester
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Liposome
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Others
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Boc-Pro-OMe (Boc-L-proline methyl ester) is a lipid compound that can be used for liposome preparation. Liposomes are the main component of vesicles with concentric phospholipid bilayer membranes, which can be used to construct drug delivery systems for anti-cancer and anti-infection fields. Highly polar water-soluble loads can be captured in the internal aqueous space of liposomes, while lipophilic loads can be distributed into the lipid bilayer and become part of the lipid bilayer. Especially for the delivery of antisense oligonucleotides, it can overcome the problems of inefficient cellular uptake and rapid loss in the body.
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- HY-164579
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Liposome
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Others
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NH2-GG-DSPE is a lipid compound that can be used for liposome preparation. Liposomes are the main component of vesicles with concentric phospholipid bilayer membranes, which can be used to construct drug delivery systems for anti-cancer and anti-infection fields. Highly polar water-soluble loads can be captured in the internal aqueous space of liposomes, while lipophilic loads can be distributed into the lipid bilayer and become part of the lipid bilayer. Especially for the delivery of antisense oligonucleotides, it can overcome the problems of inefficient cellular uptake and rapid loss in the body.
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- HY-151759
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Fluorescent Dye
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Others
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Sulfo-Cy5-TCO is a click chemistry reagent containing a TCO group. Sulfo-Cy5-TCO is water soluble dye, which is highly reactive with tetrazines and methyltetrazines with the fastest bioconjugation speed .
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- HY-157678
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Liposome
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Others
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1,2-Dilinoleoyl-sn-glycero-3-phospho-L-serine sodium is a lipid compound that can be used for liposome preparation. Liposomes are the main component of vesicles with concentric phospholipid bilayer membranes, which can be used to construct drug delivery systems for anti-cancer and anti-infection fields. Highly polar water-soluble loads can be captured in the internal aqueous space of liposomes, while lipophilic loads can be distributed into the lipid bilayer and become part of the lipid bilayer. Especially for the delivery of antisense oligonucleotides, it can overcome the problems of inefficient cellular uptake and rapid loss in the body.
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- HY-157624
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18:0-22:6 PE
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Liposome
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Others
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1-Stearoyl-2-docosahexaenoyl-sn-glycero-3-phosphoethanolamine (18:0-22:6 PE) is a lipid compound that can be used for liposome preparation. Liposomes are the main component of vesicles with concentric phospholipid bilayer membranes, which can be used to construct drug delivery systems for anti-cancer and anti-infection fields. Highly polar water-soluble loads can be captured in the internal aqueous space of liposomes, while lipophilic loads can be distributed into the lipid bilayer and become part of the lipid bilayer. Especially for the delivery of antisense oligonucleotides, it can overcome the problems of inefficient cellular uptake and rapid loss in the body.
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- HY-165975
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(2S)-3-Keto-C6-dihydrosphingosine hydrochloride
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Liposome
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Others
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(2S)-3-Keto sphinganine (d6:0) ((2S)-3-Keto-C6-dihydrosphingosine) hydrochloride is a lipid compound that can be used for liposome preparation. Liposomes are the main component of vesicles with concentric phospholipid bilayer membranes, which can be used to construct drug delivery systems for anti-cancer and anti-infection fields. Highly polar water-soluble loads can be captured in the internal aqueous space of liposomes, while lipophilic loads can be distributed into the lipid bilayer and become part of the lipid bilayer. Especially for the delivery of antisense oligonucleotides, it can overcome the problems of inefficient cellular uptake and rapid loss in the body.
|
-
| Cat. No. |
Product Name |
Type |
-
- HY-15096
-
|
FJ-776
|
Dyes
|
|
MKT-077 (FJ-776), a highly water-soluble mitochondrial dye, has significant antitumor activity . MKT-077 exhibits low cytotoxicity, and inhibits broad-spectrum human cancer cell lines (colon cancer, breast cancer, pancreatic cancer). MKT-077 inhibits the growth of tumor in nude mice enograft tumor model. Ex/Em=488/543 nm .
|
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- HY-D1367
-
|
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Fluorescent Dyes/Probes
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Sulfo-Cyanine7 carboxylic acid is a highly hydrophilic and water-soluble near-infrared dye. It improves quantum yield in the near-infrared range and has a very high molar extinction coefficient.
|
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- HY-D1376
-
|
|
Fluorescent Dyes/Probes
|
|
Sulfo-Cyanine5.5 amine potassium is a water-soluble cyanine dye suitable for far-red/near-infrared applications such as in vivo imaging. The dye has four sulfonate groups, making it highly hydrophilic and water-soluble. Like other cyanines, sulfo-Cyanine5.5 has an excellent extinction coefficient, making it a bright fluorescent marker in the far-red region. This is an amine-containing fluorescent dye. The amine group is separated from the fluorophore by a relatively long linker that facilitates conjugation. Aliphatic primary amine groups can be coupled with various electrophiles (activated esters, epoxides, etc.) and can also be used for enzymatic transamination labeling.
|
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- HY-151713
-
|
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Fluorescent Dyes/Probes
|
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Sulfo-Cy3-Methyltetrazine (figure 7 compound 5) is a click chemistry reagent containing methyltetrazine and a water-soluble dye. Sulfo-Cy3-Methyltetrazine shows good stability at physiological pH. Sulfo-Cy3-Methyltetrazine can be coupled to trans-cyclooctene and is also highly reactive towards cyclooctene .
|
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- HY-118540
-
|
Diazoresorcinol
|
Fluorescent Dyes/Probes
|
|
Resazurin (Diazoresorcinol) is a water-soluble, non-toxic, stable, membrane-permeable blue non-fluorescent dye (faintly fluorescent). Resazurin is used as a redox indicator, can be reduced to pink, highly fluorescent Resorufin (Ex=530-560 nm, Em=590 nm) in living cells. Resazurin can be used for the detection of cell viability, toxicity, proliferation, migration and invasion in cells (human, plant and animal, bacterial and fungal) .
|
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- HY-151759
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Dyes
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Sulfo-Cy5-TCO is a click chemistry reagent containing a TCO group. Sulfo-Cy5-TCO is water soluble dye, which is highly reactive with tetrazines and methyltetrazines with the fastest bioconjugation speed .
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| Cat. No. |
Product Name |
Type |
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- HY-15933
-
|
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Indicators
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TOPS is a highly water-soluble aniline derivative widely used in diagnostics and biological experiments.
|
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- HY-15913
-
|
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Indicators
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DAOS, a Trinder's reagent, is a novel highly water-soluble aniline derivative; are widely used in diagnostic tests and biochemical tests.
|
-
- HY-15918
-
|
|
Indicators
|
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HDAOS is a novel Trinder's reagent, which is a highly water-soluble aniline derivative; are widely used in diagnostic tests and biochemical tests.
|
-
- HY-N0322A
-
|
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Drug Delivery
|
|
Cholesterol Water Soluble is a major sterol in mammals, constituting 20-25% of the structural composition of the plasma membrane. The plasma membrane is highly permeable to water but relatively impermeable to ions and protons. Cholesterol Water Soluble plays an important role in determining the fluidity and permeability characteristics of membranes and the function of transporters and signaling proteins. Cholesterol Water Soluble is also an endogenous estrogen-related receptor alpha (ERRα) agonist. Cholesterol Water Soluble can be used to study the effects of cholesterol on potassium currents in inner hair cells .
|
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- HY-15932
-
|
TOOS sodium salt
|
Biochemical Assay Reagents
|
|
TOOS (TOOS sodium salt) is a highly water-soluble aniline derivative widely used in diagnostics and biological experiments. TOOS can be combined with 3-methyl-2-benzothiazolinone hydrazone hydrochloride (MBTH) to form a chromogenic system to measure oxidase activity. In the MBTH-TOOS chromogenic system, MBTH is catalytically oxidized to produce (-NH) free radicals, which react with TOOS to form colorless compounds. Furthermore, the colorless compound undergoes a disproportionation reaction to produce a blue-violet quinoid compound .
|
| Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-160429
-
|
|
Drug Derivative
|
Others
|
|
PSAR18-COOH is a derivative of PSAR extracted from patent WO2009064913A1. PSAR is a highly hydrophilic, biodegradable, non-immunogenic and water-soluble polymer that has been employed in several delivery systems for drugs or diagnostics.
|
-
- HY-40118
-
|
Boc-L-proline methyl ester
|
Liposome
|
Others
|
|
Boc-Pro-OMe (Boc-L-proline methyl ester) is a lipid compound that can be used for liposome preparation. Liposomes are the main component of vesicles with concentric phospholipid bilayer membranes, which can be used to construct drug delivery systems for anti-cancer and anti-infection fields. Highly polar water-soluble loads can be captured in the internal aqueous space of liposomes, while lipophilic loads can be distributed into the lipid bilayer and become part of the lipid bilayer. Especially for the delivery of antisense oligonucleotides, it can overcome the problems of inefficient cellular uptake and rapid loss in the body.
|
| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
| Cat. No. |
Product Name |
|
Classification |
-
- HY-151713
-
|
|
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Labeling and Fluorescence Imaging
Tetrazine
|
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Sulfo-Cy3-Methyltetrazine (figure 7 compound 5) is a click chemistry reagent containing methyltetrazine and a water-soluble dye. Sulfo-Cy3-Methyltetrazine shows good stability at physiological pH. Sulfo-Cy3-Methyltetrazine can be coupled to trans-cyclooctene and is also highly reactive towards cyclooctene .
|
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- HY-151759
-
|
|
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TCO
Labeling and Fluorescence Imaging
|
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Sulfo-Cy5-TCO is a click chemistry reagent containing a TCO group. Sulfo-Cy5-TCO is water soluble dye, which is highly reactive with tetrazines and methyltetrazines with the fastest bioconjugation speed .
|
| Cat. No. |
Product Name |
|
Classification |
-
- HY-N0322A
-
|
|
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Cholesterol
|
|
Cholesterol Water Soluble is a major sterol in mammals, constituting 20-25% of the structural composition of the plasma membrane. The plasma membrane is highly permeable to water but relatively impermeable to ions and protons. Cholesterol Water Soluble plays an important role in determining the fluidity and permeability characteristics of membranes and the function of transporters and signaling proteins. Cholesterol Water Soluble is also an endogenous estrogen-related receptor alpha (ERRα) agonist. Cholesterol Water Soluble can be used to study the effects of cholesterol on potassium currents in inner hair cells .
|
-
- HY-W019883
-
|
|
|
pH Modifiers
|
|
Dipotassium hydrogen phosphate is a highly water-soluble salt which is often used as a fertilizer, food additive and buffering agent. Dipotassium hydrogen phosphate can be used as an excipient, such as pH regulator, buffer. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .
|
-
- HY-157624
-
|
18:0-22:6 PE
|
|
Phospholipids
|
|
1-Stearoyl-2-docosahexaenoyl-sn-glycero-3-phosphoethanolamine (18:0-22:6 PE) is a lipid compound that can be used for liposome preparation. Liposomes are the main component of vesicles with concentric phospholipid bilayer membranes, which can be used to construct drug delivery systems for anti-cancer and anti-infection fields. Highly polar water-soluble loads can be captured in the internal aqueous space of liposomes, while lipophilic loads can be distributed into the lipid bilayer and become part of the lipid bilayer. Especially for the delivery of antisense oligonucleotides, it can overcome the problems of inefficient cellular uptake and rapid loss in the body.
|
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- HY-W591449
-
|
|
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Pegylated Lipids
|
|
DOPE-PEG-Azide, MW 2000 is a liposome to simulate biological phospholipid membrane. Liposomes are the main component of vesicles with concentric phospholipid bilayer membranes, which can be used to construct drug delivery systems for anti-cancer and anti-infection fields. Highly polar water-soluble payloads can be trapped in the internal aqueous space of liposomes, while lipophilic payloads can partition into and become part of the lipid bilayer. Especially for delivering antisense oligonucleotides, it can overcome problems such as inefficient cellular uptake and rapid loss in the body .
|
-
- HY-157678
-
|
|
|
Phospholipids
|
|
1,2-Dilinoleoyl-sn-glycero-3-phospho-L-serine sodium is a lipid compound that can be used for liposome preparation. Liposomes are the main component of vesicles with concentric phospholipid bilayer membranes, which can be used to construct drug delivery systems for anti-cancer and anti-infection fields. Highly polar water-soluble loads can be captured in the internal aqueous space of liposomes, while lipophilic loads can be distributed into the lipid bilayer and become part of the lipid bilayer. Especially for the delivery of antisense oligonucleotides, it can overcome the problems of inefficient cellular uptake and rapid loss in the body.
|
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