2. Metabolic Enzyme/Protease
  3. Liposome
  4. Cholesterol (Water Soluble)

Cholesterol Water Soluble can be used for the research of the effects of cholesterol on the potassium currents in inner hair cells (IHCs). Cholesterol is an integral component of the cell membrane and regulates the activity of ion channels in the lipid bilayer.

For research use only. We do not sell to patients.

Cholesterol (Water Soluble) Chemical Structure

Cholesterol (Water Soluble) Chemical Structure

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Based on 33 publication(s) in Google Scholar

Other Forms of Cholesterol (Water Soluble):

Cholesterol (Water Soluble) Related Antibodies

Top Publications Citing Use of Products

33 Publications Citing Use of MCE Cholesterol (Water Soluble)

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Description

Cholesterol Water Soluble can be used for the research of the effects of cholesterol on the potassium currents in inner hair cells (IHCs). Cholesterol is an integral component of the cell membrane and regulates the activity of ion channels in the lipid bilayer[1][2].

In Vitro

In solution of 1mM water-soluble cholesterol, the amplitude of K currents in isolated IHCs is reversely changed[2]. Note: Product is approximately 40 mg of Cholesterol per gram containing a balance of Methyl-B-cyclodextrin.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cholesterol (Water Soluble) Related Antibodies
Appearance

Solid

Color

White to off-white

SMILES

[Cholesterol (Water Soluble)]
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

H2O : 50 mg/mL (Need ultrasonic)

DMSO : 33.33 mg/mL (Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 33.33 mg/mL; Clear solution; Need ultrasonic

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥98.0%

COA (242 KB)

Handling Instructions (2659 KB)
References
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Cholesterol (Water Soluble) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cholesterol (Water Soluble)LiposomeinnerhaircellslateralwallstiffnessInhibitorinhibitorinhibit

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Inquiry Information

Product Name:
Cholesterol (Water Soluble)
Cat. No.:
HY-N0322A
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