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palmitoyl protein thioesterase

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (1) Autophagy (1) Elastase (1) Fluorescent Dye (1) Parasite (1)
By Research Areas:	Cancer (1) Infection (1) Neurological Disease (2)

4

Inhibitors & Agonists

3

Recombinant Proteins

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

ABC44	Others	Neurological Disease
ABC44 is a potent serine hydrolase inhibitor with IC₅₀s of 0.1 μM and 6.5 μM for palmitoyl protein thioesterase 1 (PPT1) in situ and in vitro, respectively. ABC44 can be used for researching infantile neuronal ceroid lipofuscinosis .

DC661 4 Publications Verification	Autophagy Apoptosis	Cancer
DC661 is a potent palmitoyl-protein thioesterase 1 (PPT1) inhibitor, inhibits autophagy, and acts as an anti-lysosomal agent. Anti-cancer activity .

JCP174	Elastase Parasite	Infection
JCP174 is an inhibitor of palmitoyl protein thioesterase-1 (TgPPT1), a depalmitoylase in the parasite T. gondii . JCP174 is also an inhibitor of porcine pancreatic elastase and human leukocyte elastase .

Mu-6S-Palm-β-Glc	Fluorescent Dye	Neurological Disease
Mu-6S-Palm-β-Glc is a fluorogenic substrate for palmitoyl-protein thioesterase (PPT). Mu-6S-Palm-β-Glc can be used for the research of neuronal ceroid lipofuscin disease in infants .

Species:	Human (2) Mouse (1)
Tag:	His (3)
Source:	HEK293 (2) Sf9 insect cells (1)

Cat. No.	Compare	Product Name	Species	Source

	PPT1 Protein, Human (HEK293, His) palmitoyl-protein thioesterase 1; PPT-1; palmitoyl-protein hydrolase 1; PPT1	Human	HEK293
	PPT1 (palmitoyl protein thioesterase 1) crucially promotes lysosomal degradation by specifically removing thioester-linked fatty acyl groups, especially palmitate, from modified cysteine residues in proteins. Its enzymatic activity is particularly suited to acyl chain lengths of 14 to 18 carbons, facilitating the breakdown of target proteins during lysosomal degradation. PPT1 Protein, Human (HEK293, His) is the recombinant human-derived PPT1 protein, expressed by HEK293 , with C-6*His labeled tag.

	PPT1 Protein, Mouse (HEK293, His) 1 Publications Verification palmitoyl-protein thioesterase 1; PPT-1; palmitoyl-protein hydrolase 1; PPT1	Mouse	HEK293
	PPT1 Protein, an enzyme in lysosomal degradation, crucially removes thioester-linked fatty acyl groups, like palmitate, from modified cysteine residues in proteins or peptides.It prefers acyl chain lengths from 14 to 18 carbons.PPT1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived PPT1 protein, expressed by HEK293 , with C-10*His labeled tag.

	ABHD10 Protein, Human (sf9, His) palmitoyl-protein thioesterase ABHD10; Acyl-protein thioesterase ABHD10	Human	Sf9 insect cells
	The ABHD10 protein is an acylprotein thioesterase that hydrolyzes fatty acids from acylated residues in proteins. It regulates mitochondrial S-depalmitoylation of peroxiredoxin-5/PRDX5 and modulates mitochondrial antioxidant capacity. ABHD10 Protein, Human (sf9, His) is the recombinant human-derived ABHD10 protein, expressed by Sf9 insect cells , with N-His labeled tag.

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