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  3. Uridine-13C5

Uridine-13C5  (Synonyms: β-Uridine-13C5)

Cat. No.: HY-B1449S10 Purity: 99.68%
SDS COA Handling Instructions

Uridine-13C5 (β-Uridine-13C5) is a 13C labeled Uridine (HY-B1449). Uridine (β-Uridine) is a nucleoside compound consisting of uracil and a ribose ring, which are linked by a β-N1- glycosyl bond.

For research use only. We do not sell to patients.

Uridine-<sup>13</sup>C<sub>5</sub> Chemical Structure

Uridine-13C5 Chemical Structure

CAS No. : 159496-16-9

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1 mg USD 483 In-stock
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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Uridine-13C5:

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  • Biological Activity

  • Purity & Documentation

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Description

Uridine-13C5 (β-Uridine-13C5) is a 13C labeled Uridine (HY-B1449). Uridine (β-Uridine) is a nucleoside compound consisting of uracil and a ribose ring, which are linked by a β-N1- glycosyl bond.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

249.16

Formula

C413C5H12N2O6

CAS No.
Unlabeled CAS

58-96-8

Appearance

Solid

Color

Off-white to light brown

SMILES

O[13C@H]1[13C@@H](O)[13C@H](N2C(NC(C=C2)=O)=O)O[13C@@H]1[13CH2]O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (401.35 mM; Need ultrasonic and warming)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.0135 mL 20.0674 mL 40.1349 mL
5 mM 0.8027 mL 4.0135 mL 8.0270 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: 99.68%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 4.0135 mL 20.0674 mL 40.1349 mL 100.3371 mL
5 mM 0.8027 mL 4.0135 mL 8.0270 mL 20.0674 mL
10 mM 0.4013 mL 2.0067 mL 4.0135 mL 10.0337 mL
15 mM 0.2676 mL 1.3378 mL 2.6757 mL 6.6891 mL
20 mM 0.2007 mL 1.0034 mL 2.0067 mL 5.0169 mL
25 mM 0.1605 mL 0.8027 mL 1.6054 mL 4.0135 mL
30 mM 0.1338 mL 0.6689 mL 1.3378 mL 3.3446 mL
40 mM 0.1003 mL 0.5017 mL 1.0034 mL 2.5084 mL
50 mM 0.0803 mL 0.4013 mL 0.8027 mL 2.0067 mL
60 mM 0.0669 mL 0.3345 mL 0.6689 mL 1.6723 mL
80 mM 0.0502 mL 0.2508 mL 0.5017 mL 1.2542 mL
100 mM 0.0401 mL 0.2007 mL 0.4013 mL 1.0034 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Uridine-13C5
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