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3-BTD  (Synonyms: 3-Benzothiazole-daphnetin)

Cat. No.: HY-D2344 Purity: 99.49%
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3-BTD (3-Benzothiazole-daphnetin) is a Catechol-O-methyltransferase (COMT) two-photon fluorescence probe. 3-BTD can also be used for biological imaging of endogenous COMT in living cells and tissue sections.

For research use only. We do not sell to patients.

3-BTD Chemical Structure

3-BTD Chemical Structure

CAS No. : 325721-44-6

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Based on 1 publication(s) in Google Scholar

3-BTD Related Antibodies

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Description

3-BTD (3-Benzothiazole-daphnetin) is a Catechol-O-methyltransferase (COMT) two-photon fluorescence probe. 3-BTD can also be used for biological imaging of endogenous COMT in living cells and tissue sections[1].

Molecular Weight

311.31

Formula

C16H9NO4S
CAS No.
Appearance

Solid

Color

Yellow to brown

SMILES

O=C1OC2=C(C(O)=CC=C2C=C1C3=NC4=C(S3)C=CC=C4)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 70 mg/mL (224.86 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.2122 mL 16.0612 mL 32.1223 mL
5 mM 0.6424 mL 3.2122 mL 6.4245 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.2122 mL 16.0612 mL 32.1223 mL 80.3058 mL
5 mM 0.6424 mL 3.2122 mL 6.4245 mL 16.0612 mL
10 mM 0.3212 mL 1.6061 mL 3.2122 mL 8.0306 mL
15 mM 0.2141 mL 1.0707 mL 2.1415 mL 5.3537 mL
20 mM 0.1606 mL 0.8031 mL 1.6061 mL 4.0153 mL
25 mM 0.1285 mL 0.6424 mL 1.2849 mL 3.2122 mL
30 mM 0.1071 mL 0.5354 mL 1.0707 mL 2.6769 mL
40 mM 0.0803 mL 0.4015 mL 0.8031 mL 2.0076 mL
50 mM 0.0642 mL 0.3212 mL 0.6424 mL 1.6061 mL
60 mM 0.0535 mL 0.2677 mL 0.5354 mL 1.3384 mL
80 mM 0.0402 mL 0.2008 mL 0.4015 mL 1.0038 mL
100 mM 0.0321 mL 0.1606 mL 0.3212 mL 0.8031 mL
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3-BTD Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

3-BTD325721-44-63-Benzothiazole-daphnetinFluorescent DyeCOMTFluorescent probeInhibitorinhibitorinhibit

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