2. Epigenetics Stem Cell/Wnt Protein Tyrosine Kinase/RTK JAK/STAT Signaling
  3. JAK
  4. AZ-3

AZ-3 is a potent and selective JAK1 inhibitor with an IC50 of 34 nM.

For research use only. We do not sell to patients.

AZ-3 Chemical Structure

AZ-3 Chemical Structure

CAS No. : 2228908-91-4

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AZ-3 Related Antibodies

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JAK1 JAK2 JAK3 Tyk2 JAK

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Description

AZ-3 is a potent and selective JAK1 inhibitor with an IC50 of 34 nM.

IC50 & Target

IC50: 34 nM (JAK1)[1]
Molecular Weight

385.48

Formula

C20H28FN7
CAS No.
SMILES

FC1=NC=C(N2C[C@H]3N(C)C[C@@H]2C3)C=C1NC4=NC(N[C@@H](CC)C)=C(C)C=N4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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AZ-3 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AZ-32228908-91-4AZ3AZ 3JAKJanus kinaseInhibitorinhibitorinhibit

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HY-112442
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