2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

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Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N0683S
    2-ambo-Vitamin E-13C6
    α-Vitamin E-13C6 is the 13C-labeled α-Vitamin E. α-Vitamin E ((+)-α-Tocopherol), a naturally occurring vitamin E form, is a potent antioxidant[1][2].
    2-ambo-Vitamin E-<sup>13</sup>C<sub>6</sub>
  • HY-17411R
    Limonin (Standard)
    Limonin (Standard) is the analytical standard of Limonin. This product is intended for research and analytical applications. Limonin inhibits HIV-1 with an EC50 of 60.0 μM. Limonin induces human colon adenocarcinoma cells apoptosis with an IC50 of 54.74 μM. Limonin has antiviral and antitumor activities.
    Limonin (Standard)
  • HY-N6818R
    5,​7,​4'-​Trimethoxyflavone (Standard)
    5,?7,?4'-Trimethoxyflavone (Standard) is the analytical standard of 5,?7,?4'-Trimethoxyflavone. This product is intended for research and analytical applications. 5,7,4’-Trimethoxyflavone can be isolated from the medicinal plant Kaempferia parviflora (KP). 5,7,4’-Trimethoxyflavone is a CFTR activator and EC50 is 64 μM. 5,7,4’-Trimethoxyflavone induces apoptosis, increases proteolytic activation of caspase-3, and degradation of ADP-ribose polymerase (PARP) protein. 5,7,4’-Trimethoxyflavone has antitumor activity. 5,7,4’-Trimethoxyflavone can be used to prevent skin aging and oxidative stress.
    5,​7,​4'-​Trimethoxyflavone (Standard)
  • HY-34740R
    Ethylmalonic acid (Standard)
    Ethylmalonic acid (Standard) is the analytical standard of Ethylmalonic acid. This product is intended for research and analytical applications. Ethylmalonic acid is non-carcinogenic potentially toxic and associated with anorexia nervosa and malonyl-CoA decarboxylase deficiency.
    Ethylmalonic acid (Standard)
  • HY-Y0127R
    D(-)-2-Aminobutyric acid (Standard)
    D(-)-2-Aminobutyric acid (Standard)
  • HY-40136R
    cis-4-Hydroxy-L-proline (Standard)
    cis-4-Hydroxy-L-proline (Standard) is the analytical standard of cis-4-Hydroxy-L-proline. This product is intended for research and analytical applications. cis-4-Hydroxy-L-proline, a proline analogue, is an inhibitor of collagen production. cis-4-Hydroxy-L-proline could inhibit fibroblast growth by preventing the deposition of triple-helical collagen on the cell layer. cis-4-Hydroxy-L-proline also depresses the growth of primary N-nitrosomethylurea-induced rat mammary tumors[4].
    cis-4-Hydroxy-L-proline (Standard)
  • HY-121309R
    Doxorubicinone (Standard)
    Doxorubicinone (Standard) is the analytical standard of Doxorubicinone. This product is intended for research and analytical applications. Doxorubicinone is a metabolite of an anti-cancer chemotherapy agent Doxorubicin. Doxorubicin is a potent human DNA topoisomerase I and topoisomerase II inhibitor with IC50s of 0.8 μM and 2.67 μM, respectively.
    Doxorubicinone (Standard)
  • HY-W017524R
    2-Methylpentanedioic acid (Standard)
    2-Methylpentanedioic acid (Standard)
  • HY-101406R
    Thyroxine sulfate (Standard)
    Thyroxine sulfate (Standard)
  • HY-B1131R
    Taurocholic acid (sodium salt hydrate) (Standard)
    Zuclopenthixol (dihydrochloride) (Standard) is the analytical standard of Zuclopenthixol (dihydrochloride). This product is intended for research and analytical applications. Zuclopenthixol ((Z)-Clopenthixol) dihydrochloride is a thioxanthene derivative which acts as a mixed dopamine D1/D2 receptor antagonist. Zuclopenthixol dihydrochloride is used in the study of schizophrenia.
    Taurocholic acid (sodium salt hydrate) (Standard)
  • HY-N0367R
    Trans-Anethole (Standard)
    Trans-Anethole (Standard) is the analytical standard of Trans-Anethole. This product is intended for research and analytical applications. Trans-Anethole ((E)-Anethole) is an orally active phenylpropene derivative found in Foeniculum vulgare that is estrogenic at low concentrations and cytotoxic at high concentrations in tumor cell lines. Trans-Anethole also has anti-aflatoxin, anti-thrombotic and anti-diabetic activities. Trans-Anethole is an important odor component in plants such as fennel, myrtle, liquorice, and camphor.
    Trans-Anethole (Standard)
  • HY-115684R
    2-Undecanol (Standard)
    Pyraoxystrobin (Standard) is the analytical standard of Pyraoxystrobin. This product is intended for research and analytical applications. Pyraoxystrobin is a QoI fungicide, with an EC50 of 0.0094 μg/mL for M. oryzae isolates. Pyraoxystrobin can be used for the research of M. oryzae in rice fields.
    2-Undecanol (Standard)
  • HY-N1393R
    2-Methoxybenzoic acid (Standard)
    2-Methoxybenzoic acid (Standard) is the analytical standard of 2-Methoxybenzoic acid. This product is intended for research and analytical applications. 2-Methoxybenzoic acid (NSC 3778) is used as an internal standard of salicylic acid and its putative biosynthetic precursors in cucumber leaves. Another known use is in the synthesis of Benextramine.
    2-Methoxybenzoic acid (Standard)
  • HY-W046906R
    (E)-Oct-2-enoic acid (Standard)
    Timosaponin BII (Standard) is the analytical standard of Timosaponin BII. This product is intended for research and analytical applications. Timosaponin BII (Prototimosaponin A III) is a steroid saponin found in the rhizomes of Anemarrhena asphodeloides. Timosaponin BII has neuronal protective, anti-inflammatory and antioxidant activities.
    (E)-Oct-2-enoic acid (Standard)
  • HY-N7127R
    (E)-m-Coumaric acid (Standard)
    (E)-m-Coumaric acid (Standard) is the analytical standard of (E)-m-Coumaric acid. This product is intended for research and analytical applications. (E)-m-Coumaric acid (3-Hydroxycinnamic acid) is an aromatic acid that highly abundant in food. (E)-m-Coumaric acid (3-Hydroxycinnamic acid) is an antioxidant.
    (E)-m-Coumaric acid (Standard)
  • HY-B0152AR
    Adenine (hydrochloride) (Standard)
    Adenine (hydrochloride) (Standard)
  • HY-N3544R
    Caryophyllene oxide (Standard)
    Caryophyllene oxide (Standard) is the analytical standard of Caryophyllene oxide. This product is intended for research and analytical applications. Caryophyllene oxide, isolated from from Hymenaea courbaril, possesses analgesic and anti-inflammatory activity.
    Caryophyllene oxide (Standard)
  • HY-W001959R
    D-Allothreonine (Standard)
    Domperidone (monomaleate) (Standard) is the analytical standard of Domperidone (monomaleate). This product is intended for research and analytical applications. Domperidone (R33812) monomaleate is an orally active and selective dopamine-2 receptor antagonist. Domperidone monomaleate acts as an antiemetic and a prokinetic agent through its effects on the chemoreceptor trigger zone and motor function of the stomach and small intestine.
    D-Allothreonine (Standard)
  • HY-W008449R
    1-Methylxanthine (Standard)
    1-Methylxanthine (Standard) is the analytical standard of 1-Methylxanthine. This product is intended for research and analytical applications. 1-Methylxanthine, a caffeine derivative, is an essential human urinary metabolite of caffeine and theophylline (1,3-dimethylxanthine, TP). 1-Methylxanthine enhances the radiosensitivity of tumor cells.
    1-Methylxanthine (Standard)
  • HY-Y1055S4
    Guanine-13C5
    Guanine-13C5 is 13C-labeled Guanine (HY-Y1055). Guanine (2-Aminohypoxanthine) is one of the fundamental components of nucleic acids (DNA and RNA). Guanine is a purine derivative, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds.
    Guanine-<sup>13</sup>C<sub>5</sub>
Cat. No. Product Name / Synonyms Application Reactivity