2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

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Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-126598
    Chaetoglobosin F
    Chaetoglobosin F is a cytochalasan-based alkaloid from Chaetomium globosum. Chaetoglobosin F exhibits cytotoxicity against human nasopharyngeal epidermoid tumor cell KB, with IC50 of 52.0 µM.
    Chaetoglobosin F
  • HY-138896
    (9E,11E)-9-Nitro-9,11-octadecadienoic acid
    (9E,11E)-9-Nitro-9,11-octadecadienoic acid (9E,11E-9-Nitro CLA) is a nitro-fatty acid, It is formed by exposure of 9Z, 11E-CLA to acidified nitrite, peroxynitrite, gaseous nitrogen dioxide, or a combination of myeloperoxidase, hydrogen peroxide, and nitrite.
    (9E,11E)-9-Nitro-9,11-octadecadienoic acid
  • HY-N0368S1
    Linalool-13C3
    Linalool-13C3 is 13C labeled α-Hexylcinnamaldehyde (HY-W014118). α-Hexylcinnamaldehyde, a compound derived from Cinnamaldehyde. α-Hexylcinnamaldehyde has the potential antimutagenic and chemosensitizing properties. α-Hexylcinnamaldehyde is widely used as an ingredient in many personal care, and as an additive in food and the pharmaceutical industry.
    Linalool-<sup>13</sup>C<sub>3</sub>
  • HY-106178D
    PMX 53 monoacetate
    PMX 53 monoacetate (3D53 monoacetate) is a potent orally active CD88 (C5aR) antagonist that inhibits C5a-induced neutrophil myeloperoxide release and chemotactic activity. PMX 53 monoacetate has an IC50 value of 20 nM against C5a-induced neutrophil myeloperoxide release. >The value is 22 nM, and the IC50 value of the chemotactic activity is 75 nM. PMX 53 monoacetate is also an agonist of MrgX2.
    PMX 53 monoacetate
  • HY-13710AR
    Dimethindene (maleate) (Standard)
    Dimethindene (maleate) (Standard) is the analytical standard of Dimethindene (maleate). This product is intended for research and analytical applications. Dimethindene maleate is a selective histamine H1 antagonist with antihistamine effects. Dimethindene maleate can be used for the research of hypersensitivity reactions.
    Dimethindene (maleate) (Standard)
  • HY-113095R
    γ-CEHC (Standard)
    Ftivazide (Standard) is the analytical standard of Ftivazide. This product is intended for research and analytical applications. Ftivazide has anti-tuberculosis activity.
    γ-CEHC (Standard)
  • HY-W050026R
    Phenylacetylglutamine (Standard)
    Phenylacetylglutamine (Standard)
  • HY-W009362S
    DL-Isocitric acid-13C4 trisodium salt
    DL-Isocitric acid-13C4 (trisodium salt) is a 13C labeled DL-Isocitric acid (trisodium salt) (HY-W009362). DL-Isocitric acid trisodium salt is an endogenous metabolite. DL-Isocitric acid trisodium salt is a substrate in the citric acid cycle. DL-Isocitric acid trisodium salt can be used as a marker for determining the composition of isocitrates in fruit products, including fruit juices.
    DL-Isocitric acid-<sup>13</sup>C<sub>4</sub> trisodium salt
  • HY-113553
    4-Aminophenylphosphorylcholine
    4-Aminophenylphosphorylcholine ((p-Aminophenyl)phosphocholine) is a probe that can be conjugated to agarose gels to generate adsorbents for affinity precipitation experiments.
    4-Aminophenylphosphorylcholine
  • HY-134314
    8-Nitro-cGMP
    8-Nitro-cGMP is an electrophilic second messenger of redox signaling that can form a protein-S-cGMP adduct in s-guanylation process. 8-Nitro-cGMP is an autophagy inducer. 8-Nitro-cGMP promotes RANKL-induced osteoclast differentiation from macrophages. 8-Nitro-cGMP has vasodilator effect, and ameliorates the vascular endothelial dysfunction in diabetic mice.
    8-Nitro-cGMP
  • HY-B1092R
    Gluconate (Calcium) (Standard)
    Gluconate (Calcium) (Standard) is the analytical standard of Gluconate (Calcium). This product is intended for research and analytical applications.
    Gluconate (Calcium) (Standard)
  • HY-N0682R
    Pyridoxine (hydrochloride) (Standard)
    Pyridoxine (hydrochloride) (Standard) is the analytical standard of Pyridoxine (hydrochloride). This product is intended for research and analytical applications. Pyridoxine hydrochloride (Pyridoxol; Vitamin B6) is a pyridine derivative. Pyridoxine (Pyridoxol; Vitamin B6) exerts antioxidant effects in cell model of Alzheimer's disease via the Nrf-2/HO-1 pathway.
    Pyridoxine (hydrochloride) (Standard)
  • HY-W017194R
    2-Phenylbutanoic acid (Standard)
    2-Phenylbutanoic acid (Standard) is the analytical standard of 2-Phenylbutanoic acid. This product is intended for research and analytical applications. 2-Phenylbutanoic acid is an endogenous metabolite.
    2-Phenylbutanoic acid (Standard)
  • HY-W010489S2
    2-Phenylacetaldehyde-d5
    2-Phenylacetaldehyde-d5 is deuterated labeled 3-Mercaptohexan-1-ol.
    2-Phenylacetaldehyde-d<sub>5</sub>
  • HY-Y0267R
    Phenoxyacetic acid (Standard)
    Phenoxyacetic acid (Standard) is the analytical standard of Phenoxyacetic acid. This product is intended for research and analytical applications. Phenoxyacetic acid is an endogenous metabolite.
    Phenoxyacetic acid (Standard)
  • HY-113144S
    L-Hexanoylcarnitine-d9
    L-Hexanoylcarnitine-d9 is deuterium labeled L-Hexanoylcarnitine. L-Hexanoylcarnitine is an acylcarnitine and is found to be associated with celiac disease.
    L-Hexanoylcarnitine-d<sub>9</sub>
  • HY-168386
    1,2-Dipalmitoyl-3-Myristoyl-rac-glycerol
    1,2-Dipalmitoyl-3-Myristoyl-rac-glycerol is a triacylglycerol in which palmitic acid (HY-N0830) is located at the sn-1 and sn-2 positions, and myristic acid (HY-N2041) is at the sn-3 position. It can be found in bovine milk fat.
    1,2-Dipalmitoyl-3-Myristoyl-rac-glycerol
  • HY-N1181R
    Tamarixetin (Standard)
    Tamarixetin (Standard) is the analytical standard of Tamarixetin. This product is intended for research and analytical applications. Tamarixetin (4'-O-Methyl Quercetin) is an orally active natural flavonoid derivative of quercetin and caseinolytic protease p (ClpP) inhibitor with anti-inflammatory, antioxidant and antitumor effects. Tamarixetin inhibits the hydrolytic activity of ClpP to the fluorescent substrate Suc-LY-AMC with an IC50 of 49.73 μM, which can be used for the study of Staphylococcus aureus infection. Tamarixetin inhibits tumor cell growth, induces apoptosis, and cell cycle arrest. Tamarixetin prevents cardiac hypertrophy by inhibiting the NFAT and AKT pathways.
    Tamarixetin (Standard)
  • HY-W000800R
    cis,cis-Muconic acid (Standard)
    Procainamide (Standard) is the analytical standard of Procainamide. This product is intended for research and analytical applications. Procainamide (Procaine amide) is a specific and potent inhibitor of DNA methyltransferase 1 (DNMT1), which reactivates the expression of tumor suppressor factors by demethylating tumor suppressor genes. Procainamide induces vacuolization in various cell types and reduces cell proliferation and migration. Procainamide relaxes airway smooth muscle by activating potassium channels. Procainamide can be used in cancer and arrhythmia research.
    cis,cis-Muconic acid (Standard)
  • HY-N14391
    Asticolorin B
    Asticolorin B is a mycotoxin metabolite from Aspergillus multicolor.
    Asticolorin B
Cat. No. Product Name / Synonyms Application Reactivity