2. Metabolic Enzyme/Protease Cell Cycle/DNA Damage Anti-infection Apoptosis PI3K/Akt/mTOR Immunology/Inflammation MAPK/ERK Pathway NF-κB
  3. Endogenous Metabolite ClpP Bacterial Apoptosis Akt Interleukin Related COX JNK p38 MAPK Reactive Oxygen Species
  4. Tamarixetin (Standard)

Tamarixetin (Standard) is the analytical standard of Tamarixetin. This product is intended for research and analytical applications. Tamarixetin (4'-O-Methyl Quercetin) is an orally active natural flavonoid derivative of quercetin and caseinolytic protease p (ClpP) inhibitor with anti-inflammatory, antioxidant and antitumor effects. Tamarixetin inhibits the hydrolytic activity of ClpP to the fluorescent substrate Suc-LY-AMC with an IC50 of 49.73 μM, which can be used for the study of Staphylococcus aureus infection. Tamarixetin inhibits tumor cell growth, induces apoptosis, and cell cycle arrest. Tamarixetin prevents cardiac hypertrophy by inhibiting the NFAT and AKT pathways.

For research use only. We do not sell to patients.

Tamarixetin (Standard) Chemical Structure

Tamarixetin (Standard) Chemical Structure

CAS No. : 603-61-2

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Description
Molecular Weight

316.26

Formula

C16H12O7
CAS No.
SMILES

O=C1C(O)=C(C2=CC=C(OC)C(O)=C2)OC3=CC(O)=CC(O)=C13
Structure Classification
Initial Source
Storage

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Purity & Documentation
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Tamarixetin (Standard) Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tamarixetin (Standard)603-61-2Endogenous MetaboliteClpPBacterialApoptosisAktInterleukin RelatedCOXJNKp38 MAPKReactive Oxygen SpeciesCaseinolytic protease PPKBProtein kinase BILCyclooxygenasec-Jun N-terminal kinasequercetinanti-oxidativecardiachypertrophySepsisInhibitorinhibitorinhibit

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