2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

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Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N6660R
    Trisdecanoin (Standard)
    Trisdecanoin (Standard) is the analytical standard of Trisdecanoin. This product is intended for research and analytical applications. Trisdecanoin (Tricaprin; Glyceryl tridecanoate) is an orally available precursor of decanoic acid (DA precursor) that can be hydrolyzed to decanoic acid. Trisdecanoin and its metabolite capric acid not only provide the body with a quick source of energy, but can also affect lipid metabolism. Trisdecanoin is a major component of medium chain triglycerides (MCT), which has preventive or inhibitory properties for abdominal aortic aneurysms (AAA), inhibition of cardiovascular disease, and anti-androgen (NSAA) and anti-hyperglycemic properties. Trisdecanoin can be used as an additive in food, medicine and cosmetics.
    Trisdecanoin (Standard)
  • HY-18732C
    L-NMMA hydrochloride
    L-NMMA (Tilarginine) hydrochloride competitively antagonizes L-arginine, and thus inhibits production of nitric oxide (NO). L-NMMA hydrochloride is utilized as NO synthase antagonist in experimental settings.
    L-NMMA hydrochloride
  • HY-129977
    7-Hydroxy coumarin sulfate potassium
    7-Hydroxy coumarin sulfate (7-HCS) potassium is a metabolite of 7-Ethoxycoumarin (HY-133091).
    7-Hydroxy coumarin sulfate potassium
  • HY-W017007SB
    3-Methyl-D-histidine-d3 hydrochloride
    3-Methyl-D-histidine-d3 hydrochloride is the deuterium labeled 3-Methyl-D-histidine hydrochloride. 3-Methyl-D-histidine hydrochloride can be found in actin and myosin and is a derivative of histidine.
    3-Methyl-D-histidine-d<sub>3</sub> hydrochloride
  • HY-114599
    8-iso Prostaglandin A1
    8-iso Prostaglandin A1 is an active substrate for Arabidopsis thaliana OPR3 (AtOPR3), with a KM of 22 μM.
    8-iso Prostaglandin A1
  • HY-E70418
    Epoxide hydrolase
    Epoxide hydrolase is an enzyme responsible for catalyzing the reaction between epoxides and water, converting epoxide groups into diols. Epoxide hydrolase plays a key role in the metabolism of environmental pollutants and lipids, contributing to detoxification, inflammation responses, and the regulation of cardiovascular system health. Additionally, epoxide hydrolase can be used in asymmetric catalytic reactions, such as the asymmetric ring-opening of epoxides, to produce chiral drug molecules.
    Epoxide hydrolase
  • HY-W034392
    Stewart-Grubbs catalyst
    Stewart-Grubbs catalyst is an effective catalyst for the cross-metathesis of olefins with a large number of allylic substituents. In addition, ChemBeads are chemically coated glass beads that improve flowability and chemical homogeneity, making them ideal for automated solid dispensing and high-throughput experiments. Notably, the manufacture of ChemBeads does not require additional chemicals or surfactants, allowing for precise dispensing of sub-milligram amounts of catalyst.
    Stewart-Grubbs catalyst
  • HY-W243879
    Tetraphenyldibenzoperiflanthene
    Tetraphenyldibenzoperiflanthene (DBP) is an organic semiconductor material with excellent electronic conduction activity. Tetraphenyldibenzoperiflanthene exhibits high mobility in organic field effect transistors (OFETs), improving device performance. Tetraphenyldibenzoperiflanthene is widely used in organic photovoltaic (OPV) materials to enhance photoelectric conversion efficiency.
    Tetraphenyldibenzoperiflanthene
  • HY-W018161R
    Hexadecanedioic acid (Standard)
    Hexadecanedioic acid (Standard) is the analytical standard of Hexadecanedioic acid. This product is intended for research and analytical applications. Hexadecanedioic acid is covalently linked to Sepharose 4B, shows better performance in terms of specificity than dye-based resins and could be used for depletion of SA from plasma samples.
    Hexadecanedioic acid (Standard)
  • HY-66006S1
    4-Acetaminophen sulfate-d4
    4-Acetaminophen sulfate-d4 is deuterated labeled 4-Acetaminophen sulfate.
    4-Acetaminophen sulfate-d<sub>4</sub>
  • HY-W743870
    5α-Dihydrodeoxycorticosterone
    5α-Dihydrodeoxycorticosterone is an intermediate product of Deoxycorticosterone (HY-113414) catalyzed by 5α-reductase. 5α-Dihydrodeoxycorticosteron levels associated with depression.
    5α-Dihydrodeoxycorticosterone
  • HY-W585837
    3-Benzylidenecamphor
    3-Benzylidenecamphor is a UV absorber with excellent photostability and antioxidant activity. 3-Benzylidenecamphor is widely used in sunscreen products to protect the skin from UV damage. 3-Benzylidenecamphor can also be used in cosmetics to improve the shelf life and safety of the product.
    3-Benzylidenecamphor
  • HY-135016
    Oleic acid triethanolamine
    Oleic acid triethanolamine (9-cis-Octadecenoic acid triethanolamine) is the most common monounsaturated fatty acid found in human adipocytes and other tissues. Oleic acid triethanolamine is a Na+/K+ ATPase activator.
    Oleic acid triethanolamine
  • HY-W075747
    SK-J014-1n
    SK-J014-1n is a nickel catalyst with high cross-coupling activity. SK-J014-1n can effectively promote organic synthesis reactions and increase reaction rate and selectivity. SK-J014-1n exhibits good catalytic performance in the synthesis of complex organic molecules.
    SK-J014-1n
  • HY-N8279
    β-1,3-1,4-Glucanase
    β-1,3-1,4-Glucanase catalyzes the hydrolysis ofβ-glucan into low molecular weight glucose polymers, thus reducing the hydrophilicity and viscosity of chyme and eliminating the anti-nutritional negative effect. β-1,3-1,4-glucanase can improve feed intake, enhance animal production, regulate cecal microbiota and increase feed conversion ratio.
    β-1,3-1,4-Glucanase
  • HY-153830
    LacCer (d18:1/16:0)
    LacCer (d18:1/16:0) (C16 Lactosylceramide (d18:1/16:0)) is an endogenous bioactive sphingolipid that can form membrane microdomains with Lyn kinase and the αi subunits of inhibitory G protein-coupled receptors (GPCRs). The levels of LacCer (d18:1/16:0) are elevated in the plasma of insulin-resistant cattle. In a mouse model of Niemann-Pick type C1 disease (a neurodegenerative cholesterol-sphingolipid lysosomal storage disorder), the expression of LacCer (d18:1/16:0) is also upregulated. LacCer (d18:1/16:0) can be used in research on metabolic diseases and neurodegenerative diseases.
    LacCer (d18:1/16:0)
  • HY-168760
    (5α)-3,6-Dioxocholan-24-oic acid
    (5α)-3,6-Dioxocholan-24-oic acid is a secondary bile acid.
    (5α)-3,6-Dioxocholan-24-oic acid
  • HY-115731
    Tocol
    (±)-Tocol is a synthetic vitamin E derivative.nlike (±)-α-tocopherol, (±)-tocol does not suppress retinol-induced erythrocyte hemolysis or increase microviscosity of rat liver phosphatidylcholine (PC) liposomes.
    Tocol
  • HY-107302
    Sandosaponin A
    Sandosaponin A (Soyasaponin Bd) is a saponin with inhibitory activity against human recombinant aldehyde reductase (hAKR1B1). Sandosaponin A can inhibit the reduction of l-idose and 4-hydroxynonenal to varying degrees. The presence of Sandosaponin A reveals the challenges posed by the masking effect of conventional aldehyde reductase inhibitors in mixtures when exploring differential aldehyde reductase inhibitors. The inhibitory mechanism of Sandosaponin A may be related to its mode of action on different substrates.
    Sandosaponin A
  • HY-139349
    Finasteride carboxaldehyde
    Finasteride carboxaldehyde (Compound M2) is the metabolite of 5α-reductase inhibitor Finasteride (HY-13635) in human bile and urine.
    Finasteride carboxaldehyde
Cat. No. Product Name / Synonyms Application Reactivity