L-NMMA hydrochloride (Synonyms: Tilarginine hydrochloride; Methylarginine hydrochloride)

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L-NMMA (Tilarginine) hydrochloride competitively antagonizes L-arginine, and thus inhibits production of nitric oxide (NO). L-NMMA hydrochloride is utilized as NO synthase antagonist in experimental settings.

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L-NMMA hydrochloride Chemical Structure

CAS No. : 156706-47-7

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Other In-stock Forms of L-NMMA hydrochloride:

L-NMMA acetate

Other Forms of L-NMMA hydrochloride:

L-NMMA acetate In-stock
L-NMMA Get quote
L-NMMA citrate Get quote

5 Publications Citing Use of MCE L-NMMA hydrochloride

Cell Viability Assay

: L-NMMA hydrochloride purchased from MedChemExpress. Usage Cited in: Nat Immunol. 2023 Jan;24(1):162-173. [Abstract]; L-NMMA acetate (200 μM; 48 h) leads to elevating ammonia and inhibiting CD8⁺ T_M cell induction, in parallel with the inhibition of NO production.

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nNOS iNOS eNOS

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Description	L-NMMA (Tilarginine) hydrochloride competitively antagonizes L-arginine, and thus inhibits production of nitric oxide (NO). L-NMMA hydrochloride is utilized as NO synthase antagonist in experimental settings^[1].
Molecular Weight	224.69
Formula	C₇H₁₇ClN₄O₂
CAS No.	156706-47-7
SMILES	N[C@@H](CCCNC(NC)=N)C(O)=O.Cl
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (265 KB) Handling Instructions (2659 KB)
References	[1]. Frey C, et al., L-thiocitrulline. A stereospecific, heme-binding inhibitor of nitric-oxide synthases. J Biol Chem. 1994 Oct 21;269(42):26083-91. [Content Brief]

L-NMMA hydrochloride Related Classifications

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This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

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Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

L-NMMA156706-47-7TilarginineMethylarginineNO SynthaseEndogenous MetaboliteNitric oxide synthasesNOScompetitiveInhibitorinhibitorinhibit

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L-NMMA hydrochloride (Synonyms: Tilarginine hydrochloride; Methylarginine hydrochloride)

Other Forms of L-NMMA hydrochloride:

L-NMMA hydrochloride Related Antibodies

5 Publications Citing Use of MCE L-NMMA hydrochloride

Featured Recommendations

•Related Small Molecules:

•Related Proteins:

View All NO Synthase Isoform Specific Products:

Biological Activity

Purity & Documentation

References

Customer Review