2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

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Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-13502R
    Mitoxantrone (Standard)
    Mitoxantrone (Standard) is the analytical standard of Mitoxantrone. This product is intended for research and analytical applications. Mitoxantrone is a potent topoisomerase II inhibitor. Mitoxantrone also inhibits protein kinase C (PKC) activity with an IC50 of 8.5 μM. Mitoxantrone induces apoptosis of B-CLL (B-chronic lymphocytic leukaemia) cells. Mitoxantrone shows antitumor activity. Mitoxantrone also has anti-orthopoxvirus activity with EC50s of 0.25 μM and and 0.8 μM for cowpox and monkeypox, respectively.
    Mitoxantrone (Standard)
  • HY-168394
    1,2-Dipalmitoyl-3-stearoyl-rac-glycerol
    1,2-Dipalmitoyl-3-stearoyl-rac-glycerol (1,2-Palmitin-3-stearin) is a triacylglycerol found in ostrich and emu oils as well as cow milk fat. The sn-1 and sn-2 positions of 1,2-Dipalmitoyl-3-stearoyl-rac-glycerol contain palmitic acid (HY-N0830), and the sn-3 position contains stearic acid (HY-B2219).
    1,2-Dipalmitoyl-3-stearoyl-rac-glycerol
  • HY-121252A
    Dopal (purity>80%)
    Dopal (purity>80%) is an aldehyde that can be generated in Parkinson's disease by enzymatic degradation of dopamine. Dopal (purity>80%) can generate reactive oxygen species (ROS), and triggers aggregation of α-synuclein. Dopal (purity>80%) elicits α-synuclein accumulation and hampers α-synuclein clearance in primary neurons.
    Dopal (purity>80%)
  • HY-W585825
    Selenoethionine
    Selenoethionine is a selenium-containing amino acid.
    Selenoethionine
  • HY-N9924
    Glucoerucin
    Glucoerucin is an aryl hydrocarbon receptor antagonist and is the 4-methylthio-butyl glucosinolate found in the seeds of Eruca sativa Mill.
    Glucoerucin
  • HY-113261S
    Oleoylcarnitine-d9
    Oleoylcarnitine-d9 is deuterium labeled Oleoylcarnitine. Oleoylcarnitine, the metabolite which accumulates through suppression of fatty acid β-oxidation, can enhance hepatocarcinogenesis via STAT3 activation.
    Oleoylcarnitine-d<sub>9</sub>
  • HY-W747648
    (+)-Norgestrel
    (+)-Norgestrel is a progestin used in birth control pills that has reproductive hormone-regulating activity. (+)-Norgestrel also plays an important role in menopausal hormone suppression.
    (+)-Norgestrel
  • HY-126745
    Corynecin V
    Corynecin V is a chloramphenicol-like bacterial metabolite originally isolated from Corynebacterium.
    Corynecin V
  • HY-Y0289R
    1-Dodecanol (Standard)
    		99.26%
    1-Dodecanol (Standard) is the analytical standard of 1-Dodecanol. This product is intended for research and analytical applications. 1-Dodecanol is an endogenous metabolite.
    1-Dodecanol (Standard)
  • HY-W096906
    Naphthacene
    Naphthacene (Benz[b]anthracene) is a fused polycyclic aromatic compound exhibiting an electron field-effect mobility of approximately 10 cm2/Vs; it is an ethylnylated acene that functions as a conducting polymer, making it suitable for use as a donor material. Its exceptional photoluminescence and quantum yield position naphthacene as a highly promising candidate for the advancement of single crystal electronic materials.
    Naphthacene
  • HY-N0060R
    Ferulic acid (Standard)
    Ferulic acid (Standard) is the analytical standard of Ferulic acid. This product is intended for research and analytical applications. Ferulic acid is a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor with IC50s of 3.78 and 12.5 μM for FGFR1 and FGFR2, respectively.
    Ferulic acid (Standard)
  • HY-B1529
    Ammonium citrate dibasic, 99%
    Ammonium citrate dibasic, 99% (Ammonium hydrogencitrate, 99%) can be used as the carbon source to prepare carbon quantum dots (CDs). Ammonium citrate dibasic, 99% is a buffering agent.
    Ammonium citrate dibasic, 99%
  • HY-117230
    Triflusulfuron-methyl
    Triflusulfuron-methyl (DPX 66037) is an active compound.
    Triflusulfuron-methyl
  • HY-141749A
    Clopidogrel carboxylic acid
    Clopidogrel carboxylic acid (CLPM) is the inactive liver metabolite of anti platelet agent, Clopidogrel (HY-15283), in human serum.
    Clopidogrel carboxylic acid
  • HY-125409
    Lysinoalanine
    Lysinoalanine is an amino acid that can be isolated from native and dinitrophenylated forms of ribonuclease after treated with alkali.
    Lysinoalanine
  • HY-W010381R
    2-Methylsuccinic acid (Standard)
    2-Methylsuccinic acid (Standard)
  • HY-124355
    4-Hydroxy hexenal
    4-Hydroxy hexenal (4-HHE) is a lipid peroxidation product derived from oxidized ω-3 fatty acids such as DHA.
    4-Hydroxy hexenal
  • HY-W391641
    F8BT
    F8BT is a polymer material with excellent photoelectric properties. F8BT is widely used in organic light-emitting diodes (OLEDs) and organic solar cells (PLEDs), and can effectively improve the luminous efficiency and energy conversion efficiency of the devices. The structure of F8BT makes it perform well in photoelectric conversion and electron transport, making it an important object of modern electronic material research.
    F8BT
  • HY-14649S6
    Retinoic acid-d3-1
    Retinoic acid-d3-1 is the deuterium labeled Retinoic acid (HY-14649). Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC50s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with Kd of 17 nM. Retinoic acid acts as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha.
    Retinoic acid-d<sub>3</sub>-1
  • HY-157666
    13:0 PC
    13:0 PC (PC(13:0/13:0)), also known as ditridecanoyl phosphatidyl choline (DTPC), is a phospholipid characterized by its unique structure that includes a polar head with a positively charged quaternary amine and a negatively charged phosphate, along with two non-polar fatty acid tails. This composition allows 13:0 PC to function effectively as a surfactant in mucus, while its amphiphilic nature makes it an essential component of cell membranes, particularly in endothelial cells, corneal epithelial cells, and fibroblasts. The liver synthesizes 13:0 PC, and it is also found in dietary sources such as eggs and soybeans. In addition, Avanti offers a diverse range of phosphatidylcholine products, including 13:0 PC, which are meticulously purified by HPLC to maintain their stability against oxidation and hydrolysis.
    13:0 PC
Cat. No. Product Name / Synonyms Application Reactivity