2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

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Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W713076
    Dihydrozeatin riboside
    Dihydrozeatin riboside is a cytokinin. Dihydrozeatin riboside can be isolated from Phaseolus vulgaris L.
    Dihydrozeatin riboside
  • HY-Z0283R
    Benzamide (Standard)
    Benzamide (Standard) is the analytical standard of Benzamide. This product is intended for research and analytical applications. Benzamide (Benzenecarboxamide) is a potent poly(ADP-ribose) polymerase (PARP) inhibitor. Benzamide has protective activity against both glutamate- and methamphetamine (METH)-induced neurotoxicity in vitro. Benzamide can attenuate the METH-induced dopamine depletions and exhibits neuroprotective activity in mice, also has no acute effect on striatal dopamine metabolism and does not reduce body temperature.
    Benzamide (Standard)
  • HY-W347540
    oxy-Arachidonoyl ethanolamide
    oxy-Arachidonoyl ethanolamide (O-alkyl-N-acylhydroxylamine) is an O-alkyl-N-acyl oxime derivative.
    oxy-Arachidonoyl ethanolamide
  • HY-N0368S2
    Linalool-d6
    Linalool-d6 is deuterated labeled Trans-Anethole (HY-N0367). Trans-Anethole ((E)-Anethole), a phenylpropene derivative isolated from Foeniculum vulgare, shows estrogenic activity at lower concentrations and cytotoxic at higher concentrations in cancer cell lines. Trans-Anethole ((E)-Anethole) contributes a large component of the odor and flavor of anise and fennel, anise myrtle, liquorice, camphor, magnolia blossoms, and star anise.
    Linalool-d<sub>6</sub>
  • HY-W020249
    Sodium ionophore X
    Sodium ionophore X, a substituted calixarene, exhibits remarkably high ionophoric properties for metal ions and serves as a synergistic agent in the solvent extraction of lanthanoids alongside a thenoyltrifluoroacetone compound. Additionally, it plays a crucial role in the preparation of potentiometric membranes.
    Sodium ionophore X
  • HY-W342243
    D-Xylonic acid
    D-Xylonic acid plays a crucial role in the interconversion of pentose and glucuronate metabolites.
    D-Xylonic acid
  • HY-13417R
    AICAR (Standard)
    AICAR (Standard) is the analytical standard of AICAR. This product is intended for research and analytical applications. AICAR (Acadesine) is an adenosine analog and a AMPK activator. AICAR regulates the glucose and lipid metabolism, and inhibits proinflammatory cytokines and iNOS production. AICAR is also an autophagy, YAP and mitophagy inhibitor.
    AICAR (Standard)
  • HY-W018501R
    Methyl p-tert-butylphenylacetate (Standard)
    Methyl p-tert-butylphenylacetate (Standard)
  • HY-W012531R
    2-Hydroxycinnamic acid (Standard)
    2-Hydroxycinnamic acid (Standard) is the analytical standard of 2-Hydroxycinnamic acid. This product is intended for research and analytical applications. 2-Hydroxycinnamic acid is a phenolic acid with antimicrobial and antioxidant properties. 2-Hydroxycinnamic acid has antimicrobial activity against Staphylococcus aureus and is not susceptible to drug resistance. 2-Hydroxycinnamic acid shows inhibitory effects on infection of HIV/SARS-CoV S pseudovirus with an IC50 of 0.3 mM. In addition, 2-Hydroxycinnamic acid has neuroprotective and antitumor activity.
    2-Hydroxycinnamic acid (Standard)
  • HY-Y0069R
    N-Acetylglycine (Standard)
    N-Acetylglycine (Standard) is the analytical standard of N-Acetylglycine. This product is intended for research and analytical applications. N-Acetylglycine (Aceturic acid) is a minor constituent of numerous foods with no genotoxicity or acute toxicity. N-acetylglycine is used in biological research of peptidomimetics.
    N-Acetylglycine (Standard)
  • HY-B0112R
    Minoxidil (Standard)
    Minoxidil (Standard) is the analytical standard of Minoxidil. This product is intended for research and analytical applications. Minoxidil (U10858) is an ATP-sensitive potassium (KATP) channel opener, a potent oral antihypertensive agent and a peripheral vasodilator that promotes vasodilation also affects hair growth. Minoxidil is also a potent inhibitor of soybean lipoxygenaseare with an IC50 of 20 μM.
    Minoxidil (Standard)
  • HY-113338A
    8-Hydroxyguanine hydrochloride
    8-Hydroxyguanine hydrochloride is a DNA damage product under oxidative stress, which is formed when hydroxyl radicals attack guanine in DNA. 8-Hydroxyguanine hydrochloride induces mutagenesis and leads to a transversion from G to T.
    8-Hydroxyguanine hydrochloride
  • HY-W664016
    Difluoroheptylazidosulfinate sodium
    Difluoroheptylazidosulfinate sodium is a compound with efficient C–H activation catalysis, which can effectively promote the formation of CC bonds in organic synthesis, thereby expanding the diverse molecular structures.
    Difluoroheptylazidosulfinate sodium
  • HY-W750551
    Glyphosate-13C,15N
    Glyphosate-13C,15N is 13C and 15N labeled Glyphosate (HY-B0863).
    Glyphosate-</sub><sup>13</sup>C,<sup>15</sup>N
  • HY-W391671
    Poly[bis(4-phenyl)(2,4,6-trimethylphenyl)amine]
    Poly[bis(4-phenyl)(2,4,6-trimethylphenyl)amine] is a poly(triarylamine) that is an organic p-type semiconductor with hole mobilities ranging from 103 to 102 cm2/V/s, which significantly improves carrier mobility. This stable, glassy polymer has an ionization potential suitable for thick film diodes. Committed to providing green alternatives that meet one or more of the 12 principles of green chemistry, this material falls into the enabling category of green alternatives, in line with the principle of "energy efficient design". In addition, while hole transport organic materials like these ensure optimal energy level alignment with the absorber layer for efficient charge collection, they can be susceptible to degradation under ambient conditions.
    Poly[bis(4-phenyl)(2,4,6-trimethylphenyl)amine]
  • HY-W654232
    L-Hydroxyproline-d4
    L-Hydroxyproline-d4 is deuterium labeled L-Hydroxyproline. L-Hydroxyproline, one of the hydroxyproline (Hyp) isomers, is a useful chiral building block in the production of many pharmaceuticals.
    L-Hydroxyproline-d<sub>4</sub>
  • HY-129734
    Aeruginosin B
    Aeruginosin B is a phenazine pigment, which can be isolated from Pseudomonas aeruginosa.
    Aeruginosin B
  • HY-N6662S
    (+)-Longifolene-13,d2
    (+)-Longifolene-13C,d2 is the 13C- and deuterium labeled (+)-Longifolene (HY-N6662). (+)-Longifolene is a sesquiterpenoid and a metabolite in rabbits. (+)-Longifolen is converted to primary, secondary or tertiary alcohols in rabbits, among which the primary alcohol is predominant.
    (+)-Longifolene-<sup>13</sup>,d<sub>2</sub>
  • HY-N3764
    Diosbulbin C
    Diosbulbin C is a diterpene lactone component, which can be extracted from traditional Chinese medicine Dioscorea bulbifera L.. Diosbulbin C possesses high anticancer activity in non-small cell lung cancer (NSCLC). Diosbulbin C could induce cell cycle arrest at G0/G1 phase in NSCLC. Diosbulbin C also inhibits the proliferation of NSCLC cells, possibly by downregulating the expression/activation of AKT, DHFR, and TYMS.
    Diosbulbin C
  • HY-W838254
    1,2-Dipentadecanoyl-sn-glycero-3-phospho-(1'-rac-glycerol) sodium
    1,2-Dipentadecanoyl-sn-glycero-3-phospho-(1'-rac-glycerol) sodium functions as an activator for the protein kinase C family and is an anionic phospholipid found in mitochondrial and microsomal membranes, playing a crucial role in the composition of lung surfactant, particularly within the membranes of lamellar bodies in the lungs.
    1,2-Dipentadecanoyl-sn-glycero-3-phospho-(1'-rac-glycerol) sodium
Cat. No. Product Name / Synonyms Application Reactivity