1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. 8-Hydroxyguanine hydrochloride

8-Hydroxyguanine hydrochloride is a DNA damage product under oxidative stress, which is formed when hydroxyl radicals attack guanine in DNA. 8-Hydroxyguanine hydrochloride induces mutagenesis and leads to a transversion from G to T.

For research use only. We do not sell to patients.

8-Hydroxyguanine hydrochloride Chemical Structure

8-Hydroxyguanine hydrochloride Chemical Structure

CAS No. : 1246818-54-1

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Description

8-Hydroxyguanine hydrochloride is a DNA damage product under oxidative stress, which is formed when hydroxyl radicals attack guanine in DNA. 8-Hydroxyguanine hydrochloride induces mutagenesis and leads to a transversion from G to T[1][2].

IC50 & Target

Human Endogenous Metabolite

 

Molecular Weight

203.59

Formula

C5H6ClN5O2

CAS No.
SMILES

O=C1NC(NC(N)=N2)=C(N1)C2=O.Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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8-Hydroxyguanine hydrochloride Related Classifications

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
8-Hydroxyguanine hydrochloride
Cat. No.:
HY-113338A
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