2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

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Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-137411
    (E/Z)-Linoleoyl-CoA
    (E/Z)-Linoleoyl-CoA is a substrate used to study the specificity and kinetics of acyl-CoA. (E/Z)-Linoleoyl-CoA has the ability to replace substrates, and its specificity can be changed by amino acid substitution, thereby affecting the reaction with different desaturases. The study of (E/Z)-Linoleoyl-CoA helps to understand the substrate specificity of mammalian front-end fatty acid desaturases and provides support for the efficient production of value-added fatty acids.
    (E/Z)-Linoleoyl-CoA
  • HY-113019
    3β,7α-Dihydroxycholest-5-enoic acid
    3β,7α-Dihydroxycholest-5-enoic acid is a derivative of cholestenoic acid.
    3β,7α-Dihydroxycholest-5-enoic acid
  • HY-113404S1
    L-Dopa-d3
    L-Dopa-d3 is deuterated labeled DL-Dopa (HY-113404). DL-Dopa is a beta-hydroxylated derivative of phenylalanine.
    L-Dopa-d<sub>3</sub>
  • HY-113295S3
    Salicyluric acid-d4
    Salicyluric acid-d4 is deuterated labeled Salicyluric acid (HY-113295). Salicyluric acid is an endogenous metabolite.
    Salicyluric acid-d<sub>4</sub>
  • HY-W022224
    3,6-Diiodo-9H-carbazole
    		99.64%
    3,6-Diiodo-9H-carbazole is an organic compound that can be used for the design and synthesis of carbazole derivatives.
    3,6-Diiodo-9H-carbazole
  • HY-B1230A
    Camylofin dihydrochloride
    Camylofin dihydrochloride is an antispasmodic drug with activity in relieving smooth muscle spasms. Camylofin dihydrochloride is used to suppress spasms during labor and to provide pharmacotherapy for ulcerative colitis. The analysis of camylofin dihydrochloride can be quantitatively determined by gas chromatography to assess its content in pharmaceutical preparations.
    Camylofin dihydrochloride
  • HY-139182
    MAGL-IN-3
    CAY10762 is an inhibitor of monoacylglycerol lipase (MAGL; IC50=34.1 nM). It reduces hydrogen peroxide-induced lactate dehydrogenase (LDH) release from Neuro2a cells when used at a concentration of 1 μM. CAY10762 (10 mg/kg) increases levels of 2-arachidonoyl glycerol in mouse brain.
    MAGL-IN-3
  • HY-113402R
    Gamma-glutamylcysteine (Standard)
    Gamma-glutamylcysteine (Standard) is the analytical standard of Gamma-glutamylcysteine. This product is intended for research and analytical applications. Gamma-glutamylcysteine (γ-Glutamylcysteine), a dipeptide containing cysteine and glutamic acid, is a precursor to glutathione (GSH). Gamma-glutamylcysteine is a cofactor for glutathione peroxidase (GPx) to increase GSH levels.
    Gamma-glutamylcysteine (Standard)
  • HY-131543
    22-Hydroxy mifepristone
    22-Hydroxy Mifepristone (RU 42698) is an orally active hydroxylated alcoholic metabolite with antiprogestational and antiglucocorticoidal activities, which contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. The relative binding affinity of 22-Hydroxy Mifepristone to the human glucocorticoid receptor is 48%.
    22-Hydroxy mifepristone
  • HY-117168
    1,2-Dilinoleoyl-sn-glycerol
    1,2-Dilinoleoyl-sn-glycerol is a diacylglycerol (DAG) with linoleic acid (HY-N0729) (18:2) side chains attached at both the sn-1 and sn-2 positions. It has been found as a component of phosphatidic acid in rat liver mitochondria and in spinach chloroplast membranes. 1,2-Dilinoleoyl-sn-glycerol is upregulated in some pregnant women and has been used as a biomarker to predict later preeclampsia in early pregnancy.
    1,2-Dilinoleoyl-sn-glycerol
  • HY-W010224R
    3-Amino-4-hydroxybenzoic acid (Standard)
    Vasicine (hydrochloride) (Standard) is the analytical standard of Vasicine (hydrochloride). This product is intended for research and analytical applications. Vasicine hydrochloride (peganine hydrochloride) is a quinazoline alkaloid isolated from Justicia adhatoda. Vasicine (peganine) possesses anti- tuberculosis activity.
    3-Amino-4-hydroxybenzoic acid (Standard)
  • HY-15127S
    Isotretinoin-d5
    Isotretinoin-d5 is the deuterium labeled Isotretinoin. Isotretinoin is an orally active vitamin A derivative and is often be used for the research of severe acne. Isotretinoin also shows anticancer activity[1][2][3].
    Isotretinoin-d<sub>5</sub>
  • HY-N8606
    N-Acetylciprofloxacin
    N-Acetylciprofloxacin is the metabolite of Ciprofloxacin (HY-B0356).
    N-Acetylciprofloxacin
  • HY-W741191
    (2E,13Z)-Octadecadienal
    (2E,13Z)-Octadecadienal is an insect sex pheromone capable of attracting clearwing moths (Synanthedon tipulformis (Clerck)) or raspberry crown borers (Pennisetia marginata (Harris))). (2E,13Z)-Octadecadienal can be isolated from (2E,13Z)-Octadecadienyl acetate, which induces strong responses in male antennae.
    (2E,13Z)-Octadecadienal
  • HY-129963
    3'-UMP disodium
    		98.92%
    3'-UMP disodium is a nucleotide, that is a component of ribonucleic acid (RNA) and would be converted to uracil in rat jejunum.
    3'-UMP disodium
  • HY-N9371R
    Crocin IV (Standard)
    Crocin IV (Standard) is the analytical standard of Crocin IV. This product is intended for research and analytical applications. Crocin IV (Dicrocin), a crocetin glycoside, is a carotenoid pigment. Crocin IV has potent antioxidant activity.
    Crocin IV (Standard)
  • HY-Y0068R
    N-Acetyl-L-phenylalanine (Standard)
    N-Acetyl-L-phenylalanine (Standard) is the analytical standard of N-Acetyl-L-phenylalanine. This product is intended for research and analytical applications. N-Acetyl-L-phenylalanine (N-Acetylphenylalanine), the principal acylamino acid in Escherichia coli, is synthesized from L-phenylalanine and acetyl-CoA.
    N-Acetyl-L-phenylalanine (Standard)
  • HY-113161S1
    L-Octanoylcarnitine-d9
    L-Octanoylcarnitine-d9 is deuterium labeled L-Octanoylcarnitine. L-Octanoylcarnitine is a plasma metabolite and a physiologically active form of octanoylcarnitine. L-Octanoylcarnitine can be used for the research of breast cancer.
    .
    L-Octanoylcarnitine-d<sub>9</sub>
  • HY-W339816
    (S,R)-Bis(monomyristoylglycero)phosphate ammonium
    (S,R)-Bis(monomyristoylglycero)phosphate ammonium actively contributes to cargo sorting by promoting the degradation and sorting of lipids, and it plays a critical role in the sorting of polyunsaturated fatty acids (PUFAs) within acidic organelles. This phospholipid features two phosphate-linked glycerol molecules arranged in a unique sn-1 glycerophospho-sn-1′ glycerol stereoconformation, with each glycerol molecule esterified to a myristic acid. Typically, it is found in the intraluminal vesicles (ILVs) of late endosomes and lysosomes.
    (S,R)-Bis(monomyristoylglycero)phosphate ammonium
  • HY-W507009
    L-Arginyl-L-alanine
    L-Arginyl-L-alanine is a dipeptide, is a vascular smooth muscle-derived relaxing factor. L-Arginyl-L-alanine increases the smooth muscle levels of cyclic GMP and nitrite in endothelium-denuded arterial rings.
    L-Arginyl-L-alanine
Cat. No. Product Name / Synonyms Application Reactivity